Estimation of the consumption CAPM with imperfect sample separation information

2008 ◽  
Vol 13 (4) ◽  
pp. 333-348 ◽  
Author(s):  
Andrei Semenov
1995 ◽  
Vol 36 (2) ◽  
pp. 503 ◽  
Author(s):  
Stratford M. Douglas ◽  
Karen Smith Conway ◽  
Gary D. Ferrier

Micromachines ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 558
Author(s):  
Hwee-Yeong Ng ◽  
Wen-Chin Lee ◽  
Chia-Te Kung ◽  
Lung-Chih Li ◽  
Chien-Te Lee ◽  
...  

Milk is a necessity for human life. However, it is susceptible to contamination and adulteration. Microfluidic analysis devices have attracted significant attention for the high-throughput quality inspection and contaminant analysis of milk samples in recent years. This review describes the major proposals presented in the literature for the pretreatment, contaminant detection, and quality inspection of milk samples using microfluidic lab-on-a-chip and lab-on-paper platforms in the past five years. The review focuses on the sample separation, sample extraction, and sample preconcentration/amplification steps of the pretreatment process and the determination of aflatoxins, antibiotics, drugs, melamine, and foodborne pathogens in the detection process. Recent proposals for the general quality inspection of milk samples, including the viscosity and presence of adulteration, are also discussed. The review concludes with a brief perspective on the challenges facing the future development of microfluidic devices for the analysis of milk samples in the coming years.


Micromachines ◽  
2019 ◽  
Vol 10 (9) ◽  
pp. 594 ◽  
Author(s):  
Annalisa Volpe ◽  
Caterina Gaudiuso ◽  
Antonio Ancona

The capability of isolating and sorting specific types of cells is crucial in life science, particularly for the early diagnosis of lethal diseases and monitoring of medical treatments. Among all the micro-fluidics techniques for cell sorting, inertial focusing combined with the laminar vortex technology is a powerful method to isolate cells from flowing samples in an efficient manner. This label-free method does not require any external force to be applied, and allows high throughput and continuous sample separation, thus offering a high filtration efficiency over a wide range of particle sizes. Although rather recent, this technology and its applications are rapidly growing, thanks to the development of new chip designs, the employment of new materials and microfabrication technologies. In this review, a comprehensive overview is provided on the most relevant works which employ inertial focusing and laminar vortex technology to sort particles. After briefly summarizing the other cells sorting techniques, highlighting their limitations, the physical mechanisms involved in particle trapping and sorting are described. Then, the materials and microfabrication methods used to implement this technology on miniaturized devices are illustrated. The most relevant evolution steps in the chips design are discussed, and their performances critically analyzed to suggest future developments of this technology.


Author(s):  
Janine M Beaman ◽  
Naheed Akhtar ◽  
David J Goldie

The stability of free βhCG (human chorionic gonadotrophin) was assessed using a dual α-fetoprotein and free βhCG assay. A significant increase in free βhCG concentration was observed in heparinized samples left unseparated for 24 h or more, the mean increase in 21 samples being 10.2% after 24 h ( P = < 0.001), increasing to 45.7% after 96 h. Similar results were also obtained in clotted samples. The effect of the increase in free βhCG on the Down's risk estimate was calculated to assess the impact of delayed sample transport and separation. The Down's risk increased in all samples with increasing separation time, but this was most significant in two samples where, using a cut off of one in 250, the risk classification changed from low risk to high risk. These results suggest that delayed sample separation can have a significant effect on screening programmes using free βhCG, particularly with respect to those patients whose risk classification is changed.


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