The Direct Synthesis of β-hydroxy-acids by Lithium Naphthalene and Acetic Acid

1970 ◽  
Vol 8 (4) ◽  
pp. 731-736 ◽  
Author(s):  
S. Watanabe ◽  
K. Suga ◽  
T. Fujita ◽  
K. Fujiyoshi
Keyword(s):  
Acetic Acid ◽  
Direct Synthesis ◽  
Hydroxy Acids

Reaction of 2-(6-Hydroxyspiro[4.5]Dec-6-Yl)-Alkanoic Acids With Aldehydes

1986 ◽  
Vol 39 (5) ◽  
pp. 799 ◽  
Author(s):  
T Fujita ◽  
S Watanabe ◽  
T Sotoguchi ◽  
K Ogawa ◽  
K Sugahara
Keyword(s):  
Acetic Acid ◽  
Vinyl Ether ◽  
Ethyl Vinyl Ether ◽  
Hydroxy Acids ◽  
Ethyl Vinyl ◽  
Catalysed Reaction ◽  
Alkanoic Acids

The acid- catalysed reaction of aldehydes or ethyl vinyl ether with β- hydroxy acids containing a spiro ring is described. For example, 7,9- dioxadispiro [4.0.5.4]pentadecan-10-one was obtained in 90% yield from the reaction of (6-hydroxyspiro[4.5]dec-6-yl)acetic acid and 1,3,5- trioxan and 8-methyl-7,9-dioxadispiro[4.0.5.4]pentadecan-10-one was obtained in 72% yield from (6-hydroxyspiro[4.5]dec-6-yl)acetic acid and ethyl vinyl ether.

Direct Synthesis of 6H-Chromeno[3,4-b]quinolin-6-ol Derivatives from Substituted 3-Nitro-2H-chromenes and 2-Nitrobenzaldehydes Mediated by Fe/AcOH System

Synthesis ◽  
2017 ◽  
Vol 50 (06) ◽  
pp. 1350-1358 ◽  
Author(s):  
Cunde Wang ◽  
Xushun Qing ◽  
Ting Wang ◽  
Chenlu Dai ◽  
Zhenjie Su
Keyword(s):  
Acetic Acid ◽  
Nucleophilic Addition ◽  
Aldol Condensation ◽  
Direct Synthesis ◽  
Reductive Cyclization ◽  
Quinoline Derivatives ◽  
Acid System ◽  
X Ray ◽  
X Ray Crystallography ◽  
Sequential Reduction

An efficient iron/acetic acid system-mediated reductive cyclization reaction of substituted 2-aryl-3-nitro-2H-chromenes with substituted 2-nitrobenzaldehydes for the synthesis of 6-aryl-6H-chromeno[3,4-b]quinolines was developed. This reaction involves the sequential reduction, hydrolysis, aldol condensation, intramolecular addition, and the nucleophilic addition of substituted 2-aryl-3-nitro-2H-chromenes with substituted 2-nitrobenzaldehydes to give the corresponding 6H-chromeno[3,4-b]quinolines. This transformation provides a straightforward synthetic protocol for constructing substituted 6H-chromeno[3,4-b]quinoline derivatives. The structures of three typical products were confirmed by X-ray crystallography.

ChemInform Abstract: Direct Synthesis of Acetic Acid from Synthesis Gas over Rh-Mn-Zr-Li/SiO2 Catalyst.

ChemInform ◽  
1987 ◽  
Vol 18 (14) ◽  
Author(s):  
T. NAKAJO ◽  
K. SANO ◽  
S. MATSUHIRA ◽  
H. ARAKAWA
Keyword(s):  
Acetic Acid ◽  
Synthesis Gas ◽  
Direct Synthesis

Preparation of Ni–Cu Bimetallic Catalyst and its Properties for the Direct Synthesis of Acetic Acid from Methanol and Carbon Monoxide

2012 ◽  
Vol 608-609 ◽  
pp. 1383-1386
Author(s):  
Jun Feng Wen ◽  
Xia Liu
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Carbon Monoxide ◽  
Acetic Acid ◽  
Bimetallic Catalysts ◽  
Bimetallic Catalyst ◽  
Direct Synthesis ◽  
Catalytic Activities ◽  
Supported Ni ◽  
Scanning Electron

Active carbon (AC) supported Ni–Cu bimetallic catalysts for the direct synthesis of acetic acid (AcOH) from CH3OH and CO were synthesized and investigated. The synthesized catalysts were fully characterized using surface comparator and scanning electron microscopy (SEM) techniques. The catalytic activities were investigated by the initial experiments. The experimental results showed that Ni–Cu /AC catalysts were efficient for the direct synthesis of AcOH. The conversion of CH3OH was higher than 15.7 % .

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