Reaction of 2-(6-Hydroxyspiro[4.5]Dec-6-Yl)-Alkanoic Acids With Aldehydes
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The acid- catalysed reaction of aldehydes or ethyl vinyl ether with β- hydroxy acids containing a spiro ring is described. For example, 7,9- dioxadispiro [4.0.5.4]pentadecan-10-one was obtained in 90% yield from the reaction of (6-hydroxyspiro[4.5]dec-6-yl)acetic acid and 1,3,5- trioxan and 8-methyl-7,9-dioxadispiro[4.0.5.4]pentadecan-10-one was obtained in 72% yield from (6-hydroxyspiro[4.5]dec-6-yl)acetic acid and ethyl vinyl ether.
1998 ◽
Vol 199
(6)
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pp. 997-1002
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2005 ◽
Vol 243
(2)
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pp. 317-322
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2009 ◽
Vol 473
(1-3)
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pp. 30-33
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1999 ◽
Vol 64
(9)
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pp. 3364-3368
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1955 ◽
Vol 34
(4)
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pp. 235???240
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