scholarly journals Transgenic mouse models generated by hydrodynamic transfection for genetic studies of liver cancer and preclinical testing of anti-cancer therapy

2015 ◽  
Vol 138 (7) ◽  
pp. 1601-1608 ◽  
Author(s):  
Hye-Lim Ju ◽  
Kwang-Hyub Han ◽  
Jong Doo Lee ◽  
Simon Weonsang Ro
Keyword(s):  
Cancer Therapy ◽  
Liver Cancer ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Transgenic Mouse Models ◽  
Genetic Studies ◽  
Preclinical Testing ◽  
Anti Cancer ◽  
Hydrodynamic Transfection

scholarly journals Disregulation of E-cadherin in transgenic mouse models of liver cancer

2004 ◽  
Vol 84 (9) ◽  
pp. 1137-1147 ◽  
Author(s):  
Diego F Calvisi ◽  
Sara Ladu ◽  
Elizabeth A Conner ◽  
Valentina M Factor ◽  
Snorri S Thorgeirsson
Keyword(s):  
Liver Cancer ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Transgenic Mouse Models ◽  
E Cadherin

Transgenic mouse models of type I diabetes

Diabetes ◽  
1990 ◽  
Vol 39 (8) ◽  
pp. 879-884 ◽  
Author(s):  
M. A. Lipes ◽  
G. S. Eisenbarth
Keyword(s):  
Transgenic Mouse ◽  
Mouse Models ◽  
Type I Diabetes ◽  
Type I ◽  
Transgenic Mouse Models

Exploring Nanoemulsion for Liver Cancer Therapy

2020 ◽  
Vol 16 (4) ◽  
pp. 260-268
Author(s):  
Tanmay Upadhyay ◽  
Vaseem A. Ansari ◽  
Usama Ahmad ◽  
Nazneen Sultana ◽  
Juber Akhtar
Keyword(s):  
Cancer Therapy ◽  
Liver Cancer ◽  
Treatment Plan ◽  
Chemotherapeutic Drugs ◽  
Drug Delivery Vehicles ◽  
Chronic Hepatitis B Virus ◽  
Anti Cancer ◽  
B Virus ◽  
Delivery Vehicles ◽  
Liquid Dosage Form

Cancer is a leading cause of mortality worldwide, accounting for 8.8 million deaths in 2015. Among these, at least 0.78 million people died of liver cancer alone. The recognized risk factors for liver cancer include chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, exposure to dietary aflatoxin, fatty liver disease, alcohol-induced cirrhosis, obesity, smoking, diabetes, and iron overload. The treatment plan for early diagnosed patients includes radiation therapy, tumour ablation, surgery, immunotherapy, and chemotherapy. Some sort of drug delivery vehicles has to be used when the treatment plan is targeted chemotherapy. Nanoemulsions are a class of biphasic liquid dosage form which are mixtures of oil and water stabilized by a surfactant. They are either transparent or bluish in hue and serve as a wonderful carrier system for chemotherapeutic drugs. These vehicles have a particle size in the range of 20-200 nm allowing them to be delivered successfully in the deepest of tissues. Recent publications on nanoemulsions reveal their acceptance and a popular choice for delivering both synthetic and herbal drugs to the liver. This work focuses on some anti-cancer agents that utilized the advantages of nanoemulsion for liver cancer therapy.

scholarly journals Characterization of tumor‐associated macrophages in prostate cancer transgenic mouse models

The Prostate ◽  
2021 ◽  
Author(s):  
Amber E. Groot ◽  
Kayla V. Myers ◽  
Timothy E. G. Krueger ◽  
Ashley L. Kiemen ◽  
Natalia H. Nagy ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Transgenic Mouse Models ◽  
Tumor Associated Macrophages
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