scholarly journals Measuring the health-related quality of life and sexual functioning of patients with rectal cancer: Does type of treatment matter?

2013 ◽  
Vol 134 (4) ◽  
pp. 979-987 ◽  
Author(s):  
Marjan J. Traa ◽  
Ricardo G. Orsini ◽  
Brenda L. Den Oudsten ◽  
Jolanda De Vries ◽  
Jan A. Roukema ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Sexual Functioning ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Impact of Short-Term Preoperative Radiotherapy on Health-Related Quality of Life and Sexual Functioning in Primary Rectal Cancer: Report of a Multicenter Randomized Trial

2005 ◽  
Vol 23 (9) ◽  
pp. 1847-1858 ◽  
Author(s):  
Corrie A.M. Marijnen ◽  
Cornelis J.H. van de Velde ◽  
Hein Putter ◽  
Mandy van den Brink ◽  
Cornelis P. Maas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Sexual Functioning ◽  
Preoperative Radiotherapy ◽  
Health Related Quality ◽  
Short Term ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Background Few prospective studies have been performed about the impact of preoperative radiotherapy (PRT) or total mesorectal excision (TME) on health-related quality of life (HRQL) and sexual functioning in patients with resectable rectal cancer. This report describes the HRQL and sexual functioning of 990 patients who underwent TME and were randomly assigned to short-term PRT (5 × 5 Gy). Patients and Methods The Rotterdam Symptom Check List supplemented with additional items was used with questionnaires before treatment and at 3, 6, 12, 18, and 24 months after surgery. Patients without a recurrence the first 2 years were analyzed (n = 990). Results Few differences were found in HRQL between patients treated with or without PRT. Daily activities were significantly less for PRT patients 3 months postoperatively. Irradiated patients recovered slower from defecation problems than TME-only patients (P = .006). PRT had a negative effect on sexual functioning in males (P = .004) and females (P < .001). Irradiated males had more ejaculation disorders (P = .002), and erectile functioning deteriorated over time (P < .001). PRT had similar effects in patients who underwent a low anterior resection (LAR) versus an abdominoperineal resection (APR). Patients with an APR scored better on the physical (P = .004) and psychologic dimension (P = .007) than LAR patients, but worse on voiding (P = .0007). Conclusion Short-term PRT leads to more sexual dysfunction, slower recovery of bowel function, and impaired daily activity postoperatively. However, this does not seriously affect HRQL. The comparison between LAR and APR patients demonstrates that the existence of a permanent stoma is not the only determinant of HRQL.

scholarly journals Effect of Hysterectomy vs Medical Treatment on Health-Related Quality of Life and Sexual Functioning

JAMA ◽  
2004 ◽  
Vol 291 (12) ◽  
pp. 1447 ◽  
Author(s):  
Miriam Kuppermann ◽  
R. Edward Varner ◽  
Robert L. Summitt, Jr ◽  
Lee A. Learman ◽  
Christine Ireland ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Medical Treatment ◽  
Sexual Functioning ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Long-Term Health-Related Quality of Life in Patients With Rectal Cancer After Preoperative Short-Course and Long-Course (Chemo) Radiotherapy

2016 ◽  
Vol 15 (3) ◽  
pp. e93-e99 ◽  
Author(s):  
Lisette M. Wiltink ◽  
Remi A. Nout ◽  
Jochem R.N. van der Voort van Zyp ◽  
Heleen M. Ceha ◽  
Marta Fiocco ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Health Related Quality ◽  
Short Course ◽  
Related Quality ◽  
Health Related ◽  
Long Course

scholarly journals Health-Related Quality of Life Among Long-Term Rectal Cancer Survivors With an Ostomy: Manifestations by Sex

2009 ◽  
Vol 27 (28) ◽  
pp. 4664-4670 ◽  
Author(s):  
Robert S. Krouse ◽  
Lisa J. Herrinton ◽  
Marcia Grant ◽  
Christopher S. Wendel ◽  
Sylvan B. Green ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Short Form ◽  
Well Being ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

Purpose Intestinal stomas can pose significant challenges for long-term (≥ 5 years) rectal cancer (RC) survivors. Specifying common challenges and sociodemographic or clinical differences will further the development of tailored interventions to improve health-related quality of life (HRQOL). Patients and Methods This was a matched cross-sectional study of long-term RC survivors conducted in three Kaiser Permanente regions. The mailed questionnaire included the modified City of Hope Quality of Life-Ostomy (mCOH-QOL-Ostomy) and Medical Outcomes Study 36-Item Short-Form Health Survey, version 2 (SF-36v2). Groups surveyed were permanent ostomates (cases) and those who did not require an ostomy (controls). RC survivors were matched on sex, age, and time since diagnosis. Comparisons between groups used regression analysis with adjustment for age, comorbidity score, history of radiation therapy, income, and work status. Results Response rate was 54% (491 of 909). Cases and controls had similar demographic characteristics. On the basis of the mCOH-QOL-Ostomy, both male and female cases had significantly worse social well-being compared with controls, while only female cases reported significantly worse overall HRQOL and psychological well-being. For younger females (< age 75 years), ostomy had a greater impact on physical well-being compared with older females. Based on the SF-36v2, statistically significant and meaningful differences between female cases and controls were observed for seven of the eight scales and on the physical and mental component summary scores. Conclusion Men and women report a different profile of challenges, suggesting the need for targeted or sex-specific interventions to improve HRQOL in this population. This may include focus on physical HRQOL for female ostomy survivors younger than age 75.

scholarly journals Patient-Physician Communication About Health-Related Quality-of-Life Problems: Are Non-Hodgkin Lymphoma Survivors Willing to Talk?

2013 ◽  
Vol 31 (31) ◽  
pp. 3964-3970 ◽  
Author(s):  
Neeraj K. Arora ◽  
Roxanne E. Jensen ◽  
Nadiyah Sulayman ◽  
Ann S. Hamilton ◽  
Arnold L. Potosky
Keyword(s):  
Quality Of Life ◽  
Sexual Functioning ◽  
Daily Functioning ◽  
Health Related Quality ◽  
Non Hodgkin Lymphoma ◽  
Follow Up Care ◽  
Related Quality ◽  
Health Related

Purpose To investigate non-Hodgkin lymphoma (NHL) survivors' willingness to discuss health-related quality-of-life (HRQOL) problems with their follow-up care physician. Patients and Methods Willingness to discuss HRQOL problems (physical, daily, emotional, social, and sexual functioning) was examined among 374 NHL survivors, 2 to 5 years postdiagnosis. Survivors were asked if they would bring up HRQOL problems with their physician and indicate reasons why not. Logistic regression models examined the association of patient sociodemographics, clinical characteristics, follow-up care variables, and current HRQOL scores with willingness to discuss HRQOL problems. Results Overall, 94%, 82%, 76%, 43%, and 49% of survivors would initiate discussions of physical, daily, emotional, social, and sexual functioning, respectively. Survivors who indicated their physician “always” spent enough time with them or rated their care as “excellent” were more willing to discuss HRQOL problems (P < .05). Survivors reporting poorer physical health were less willing to discuss their daily functioning problems (P < .001). Men were more willing to discuss sexual problems than women (P < .001). One in three survivors cited “nothing can be done” as a reason for not discussing daily functioning problems, and at least one in four cited “this was not their doctor's job” and a preference to “talk to another clinician” as reasons for not discussing emotional, social, and sexual functioning. Conclusion NHL survivors' willingness to raise HRQOL problems with their physician varied by HRQOL domain. For some domains, even when survivors were experiencing problems, they may not discuss them. To deliver cancer care for the whole patient, interventions that facilitate survivor-clinician communication about survivors' HRQOL are needed.

Health-Related Quality of Life and Tamoxifen in Breast Cancer Prevention: A Report From the National Surgical Adjuvant Breast and Bowel Project P-1 Study

1999 ◽  
Vol 17 (9) ◽  
pp. 2659-2659 ◽  
Author(s):  
Richard Day ◽  
Patricia A. Ganz ◽  
Joseph P. Costantino ◽  
Walter M. Cronin ◽  
D. Lawrence Wickerham ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Prevention ◽  
Sexual Functioning ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
Bowel Project

PURPOSE: This is the initial report from the health-related quality of life (HRQL) component of the National Surgical Adjuvant Breast and Bowel Project Breast Cancer Prevention Trial. This report provides an overview of HRQL findings, comparing tamoxifen and placebo groups, and advice to clinicians counseling women about the use of tamoxifen in a prevention setting. PATIENTS AND METHODS: This report covers the baseline and the first 36 months of follow-up data on 11,064 women recruited over the first 24 months of the study. Findings are presented from the Center for Epidemiological Studies–Depression Scale (CES-D), the Medical Outcomes Study 36-Item Short Form Health Status Survey (MOS SF-36) and sexual functioning scale, and a symptom checklist. RESULTS: No differences were found between placebo and tamoxifen groups for the proportion of participants scoring above a clinically significant level on the CES-D. No differences were found between groups for the MOS SF-36 summary physical and mental scores. The mean number of symptoms reported was consistently higher in the tamoxifen group and was associated with vasomotor and gynecologic symptoms. Significant increases were found in the proportion of women on tamoxifen reporting problems of sexual functioning at a definite or serious level, although overall rates of sexual activity remained similar. CONCLUSION: Women need to be informed of the increased frequency of vasomotor and gynecologic symptoms and problems of sexual functioning associated with tamoxifen use. Weight gain and depression, two clinical problems anecdotally associated with tamoxifen treatment, were not increased in frequency in this trial in healthy women, which is good news that also needs to be communicated.

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