scholarly journals Health-Related Quality of Life and Functional Outcomes Following Curative Treatments for Rectal Cancer: A Population-Level Study in England

2016 ◽  
Vol 96 (2) ◽  
pp. S124-S125
Author(s):  
A. Downing ◽  
P. Finan ◽  
D. Sebag-Montefiore ◽  
P. Wright ◽  
J. Thomas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Functional Outcomes ◽  
Population Level ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Health-related Quality of Life and Functional Outcomes in 5-year Survivors After Pancreaticoduodenectomy

2017 ◽  
Vol 266 (4) ◽  
pp. 685-692 ◽  
Author(s):  
Zhi Ven Fong ◽  
Donna M. Alvino ◽  
Carlos Fernández-del Castillo ◽  
Ryan D. Nipp ◽  
Lara N. Traeger ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Outcomes ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Long-Term Health-Related Quality of Life in Patients With Rectal Cancer After Preoperative Short-Course and Long-Course (Chemo) Radiotherapy

2016 ◽  
Vol 15 (3) ◽  
pp. e93-e99 ◽  
Author(s):  
Lisette M. Wiltink ◽  
Remi A. Nout ◽  
Jochem R.N. van der Voort van Zyp ◽  
Heleen M. Ceha ◽  
Marta Fiocco ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Health Related Quality ◽  
Short Course ◽  
Related Quality ◽  
Health Related ◽  
Long Course

scholarly journals Restarting antiplatelet therapy after spontaneous intracerebral hemorrhage

Neurology ◽  
2018 ◽  
Vol 91 (1) ◽  
pp. e26-e36 ◽  
Author(s):  
Ching-Jen Chen ◽  
Dale Ding ◽  
Thomas J. Buell ◽  
Fernando D. Testai ◽  
Sebastian Koch ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Intracerebral Hemorrhage ◽  
Functional Outcomes ◽  
Primary Outcome ◽  
Modified Rankin Scale ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Secondary Outcomes

ObjectiveTo compare the functional outcomes and health-related quality of life metrics of restarting vs not restarting antiplatelet therapy (APT) in patients presenting with intracerebral hemorrhage (ICH) in the ERICH (Ethnic/Racial Variations of Intracerebral Hemorrhage) study.MethodsAdult patients aged 18 years and older who were on APT before ICH and were alive at hospital discharge were included. Patients were dichotomized based on whether or not APT was restarted after hospital discharge. The primary outcome was a modified Rankin Scale score of 0–2 at 90 days. Secondary outcomes were excellent outcome (modified Rankin Scale score 0–1), mortality, Barthel Index, and health status (EuroQol–5 dimensions [EQ-5D] and EQ-5D visual analog scale scores) at 90 days.ResultsThe APT and no APT cohorts comprised 127 and 732 patients, respectively. Restarting APT was associated with lower rates of good functional outcome (36.5% vs 40.8%; p = 0.021) and lower Barthel Index scores at 90 days (p = 0.041). The 2 cohorts were then matched in a 1:1 ratio, and the matched cohorts each comprised 107 patients. No difference in primary outcome was observed between restarting vs not restarting APT (35.5% vs 43.9%; p = 0.105). There were also no differences between the secondary outcomes of the 2 cohorts.ConclusionRestarting APT in patients with ICH of mild to moderate severity after acute hospitalization is not associated with worse functional outcomes or health-related quality of life at 90 days. In patients with significant cardiovascular risk factors who experience an ICH, restarting APT remains the decision of the treating practitioner.

scholarly journals Health-Related Quality of Life Among Long-Term Rectal Cancer Survivors With an Ostomy: Manifestations by Sex

2009 ◽  
Vol 27 (28) ◽  
pp. 4664-4670 ◽  
Author(s):  
Robert S. Krouse ◽  
Lisa J. Herrinton ◽  
Marcia Grant ◽  
Christopher S. Wendel ◽  
Sylvan B. Green ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Short Form ◽  
Well Being ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

Purpose Intestinal stomas can pose significant challenges for long-term (≥ 5 years) rectal cancer (RC) survivors. Specifying common challenges and sociodemographic or clinical differences will further the development of tailored interventions to improve health-related quality of life (HRQOL). Patients and Methods This was a matched cross-sectional study of long-term RC survivors conducted in three Kaiser Permanente regions. The mailed questionnaire included the modified City of Hope Quality of Life-Ostomy (mCOH-QOL-Ostomy) and Medical Outcomes Study 36-Item Short-Form Health Survey, version 2 (SF-36v2). Groups surveyed were permanent ostomates (cases) and those who did not require an ostomy (controls). RC survivors were matched on sex, age, and time since diagnosis. Comparisons between groups used regression analysis with adjustment for age, comorbidity score, history of radiation therapy, income, and work status. Results Response rate was 54% (491 of 909). Cases and controls had similar demographic characteristics. On the basis of the mCOH-QOL-Ostomy, both male and female cases had significantly worse social well-being compared with controls, while only female cases reported significantly worse overall HRQOL and psychological well-being. For younger females (< age 75 years), ostomy had a greater impact on physical well-being compared with older females. Based on the SF-36v2, statistically significant and meaningful differences between female cases and controls were observed for seven of the eight scales and on the physical and mental component summary scores. Conclusion Men and women report a different profile of challenges, suggesting the need for targeted or sex-specific interventions to improve HRQOL in this population. This may include focus on physical HRQOL for female ostomy survivors younger than age 75.

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