scholarly journals Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1)in vitroandin vivoby increasing the activity of the p-glycoproteinviaactivation of p38

2008 ◽  
Vol 123 (11) ◽  
pp. 2532-2542 ◽  
Author(s):  
Christoph Sauvant ◽  
Martin Nowak ◽  
Claudia Wirth ◽  
Bettina Schneider ◽  
Anne Riemann ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Drug Resistance ◽  
Cancer Cells ◽  
Multi Drug Resistance ◽  
Prostate Cancer Cells ◽  
Rat Prostate

Chronic hypoxia promotes an aggressive phenotype in rat prostate cancer cells

2007 ◽  
Vol 41 (7) ◽  
pp. 788-797 ◽  
Author(s):  
Omar Alqawi ◽  
Hong P. Wang ◽  
Myrna Espiritu ◽  
Gurmit Singh
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Chronic Hypoxia ◽  
Prostate Cancer Cells ◽  
Aggressive Phenotype ◽  
Rat Prostate

A Study of Membrane Activity in Rat Prostate Cancer Cells: An Evaluation of the FM1–43 Dye Technique

2000 ◽  
Vol 20 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Maria E. Mycielska ◽  
Monika Schäfer ◽  
Scott P. Fraser ◽  
Mustafa B. A. Djamgoz ◽  
C. Lindsay Bashford
Keyword(s):  
Prostate Cancer ◽  
Cell Division ◽  
Cancer Cells ◽  
Cell Lines ◽  
Prostate Cancer Cells ◽  
Excitable Cells ◽  
Membrane Activity ◽  
Variable Pattern ◽  
Cells In Culture ◽  
Rat Prostate

A study was initiated to test whether the FM1–43 dye technique could beapplied to the study of endocytic membrane activity in two rodent prostatecancer (MAT-LyLu and AT-2) cell lines of markedly different metastaticability. The lipophilic dye FM1–43, which has frequently been used tomonitor endo/exocytic activity in excitable cells was employed. We found,as in excitable tissues, that both strongly metastatic (MAT-LyLu) andweakly metastatic (AT-2) cells in culture take up FM1–43 to give vesicularstaining of a variable pattern, which appeared to differ between the twocell lines. However, unlike excitable tissues, neither cell linesubsequently released the dye. Indeed, both cell lines retained the dyethrough several rounds of cell division suggesting that dye incorporatedby cells does not enter the endo/exocytotic cycle. Uptake of dye wasindependent of temperature, Na+/K+ gradients, pH or metabolism. Wesuggest that passive accumulation of FM1–43 can occur in cancer cells andshould not, automatically, be interpreted as evidence of endocytosis.

Rat Prostate Cancer Cells Contain Functional Receptors for Transforming Growth Factorβ*

Endocrinology ◽  
1990 ◽  
Vol 126 (2) ◽  
pp. 818-825 ◽  
Author(s):  
SYDNEY A. SHAIN ◽  
ALAN L. LIN ◽  
JUDITH D. ROGER ◽  
ANDREW G. KARAGANIS
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Rat Prostate

Homotypic cell-cell contacts stimulate the motile activity of rat prostate cancer cells

2001 ◽  
Vol 88 (7) ◽  
pp. 776-786 ◽  
Author(s):  
Z. Madeja ◽  
K. Miȩkus ◽  
J. Sroka ◽  
M.B.A. Djamgoz ◽  
W. Korohoda
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Cell Contacts ◽  
Rat Prostate ◽  
Motile Activity ◽  
Cell Cell
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