scholarly journals Betel quid not containing tobacco and oral cancer: A report on a case–control study in Papua New Guinea and a meta-analysis of current evidence

2007 ◽  
Vol 120 (6) ◽  
pp. 1318-1323 ◽  
Author(s):  
Steven J. Thomas ◽  
Christopher J. Bain ◽  
Diana Battistutta ◽  
Andrew R. Ness ◽  
Darius Paissat ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Papua New Guinea ◽  
Case Control Study ◽  
Meta Analysis ◽  
New Guinea ◽  
Case Control ◽  
Betel Quid ◽  
Current Evidence ◽  
Control Study

scholarly journals Betel quid not containing tobacco and oral leukoplakia: A report on a cross-sectional study in Papua New Guinea and a meta-analysis of current evidence

2008 ◽  
Vol 123 (8) ◽  
pp. 1871-1876 ◽  
Author(s):  
Steven J. Thomas ◽  
Ross Harris ◽  
Andrew R. Ness ◽  
Joachim Taulo ◽  
Robert Maclennan ◽  
...  
Keyword(s):  
Papua New Guinea ◽  
Meta Analysis ◽  
New Guinea ◽  
Cross Sectional Study ◽  
Oral Leukoplakia ◽  
Betel Quid ◽  
Current Evidence ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Betel Quid, Smoking and Alcohol Dependency among Patients with Oral Potentially Malignant Disorders and Oral Cancer in Sri Lanka; A Preliminary Case-control Study

2021 ◽  
Vol 6 (3) ◽  
pp. 207-212
Author(s):  
Sumali R. Sumithrarachchi ◽  
W.A.Udari.C. Pemasiri ◽  
A.M.S. Deepanie. Pathiranage ◽  
Primali R. Jayasooriya
Keyword(s):  
Alcohol Use ◽  
Oral Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Betel Quid ◽  
Oral Lesions ◽  
Oral Potentially Malignant Disorders ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
Control Study

Introduction: Oral cancer and Oral Potentially Malignant Disorders (OPMDs) arising due to risk habits like betel quid (BQ) chewing, smoking and alcohol use are preventable despite the high prevalence and poor survival rates. However, dependence to risk habits has become a barrier to prevent OPMDs and oral cancer. Objectives: This study was conducted to determine the dependence to risk habits among patients with such oral lesions, and the quitting among dependent users after diagnosis. Materials and method: A case-control study was conducted among 100 participants, 50 diagnosed with OPMDs and oral cancer from two Oral and Maxillo Facial clinics in Sri Lanka and a similar control group without any oral lesions. All participants practiced one or more risk habits such as BQ chewing, smoking and/or alcohol use. Dependence was assessed using Sinhala language translations of standardized scales such as Betel Quid Dependence Scale for BQ chewers, Fagerstrom Test for Nicotine Dependence for tobacco smokers and CAGE (“Cut down”, “Annoyed”, “Guilty” and “Eye opener”) scale for alcohol users. Results: Dependence on habits was more among the case group (BQ-93%; smoking-14%; alcohol-66%). Quitting rates of BQ and alcohol among those who were diagnosed with oral cancer [BQ (89%), alcohol (89%)] were higher (p<0.05) than those with OPMDs [BQ (50%), alcohol (22%)]. Lack of awareness due to low socio-economic status (97%) was a significant association for BQ dependence (p=0.01).Conclusion: In conclusion, development of OPMDs and oral cancer increases with dependence to BQ chewing, smoking and alcohol use. Increased awareness about OPMDs and its risk of malignancy is needed among public. Prevention of dependence to these risk habits also becomes essential.  

A Case-Control Study of Diet in Newly Diagnosed NIDDM in the Wanigela People of Papua New Guinea

Diabetes Care ◽  
1996 ◽  
Vol 19 (5) ◽  
pp. 457-462 ◽  
Author(s):  
A. M. Hodge ◽  
J. Montgomery ◽  
G. K. Dowse ◽  
B. Mavo ◽  
T. Watt ◽  
...  
Keyword(s):  
Papua New Guinea ◽  
Case Control Study ◽  
New Guinea ◽  
Case Control ◽  
Newly Diagnosed ◽  
Control Study

scholarly journals The Decisive Case-Control Study Elaborates the Null Association between ESR1 XbaI and Osteoarthritis in Asians: A Case–Control Study and Meta-Analysis

Genes ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 404
Author(s):  
Yu-Hao Huang ◽  
Wen-Hui Fang ◽  
Dung-Jang Tsai ◽  
Yu-Hsuan Chen ◽  
Yu-Chiao Wang ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Gender Difference ◽  
Sequential Analysis ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Current Evidence ◽  
Trial Sequential Analysis ◽  
Knee Oa ◽  
Control Study

(1) Background: The prevalence of knee osteoarthritis (OA) in women is significantly higher than in men. The estrogen receptor α (ERα) has been considered to play a key role due to a large gender difference in its expression. ERα is encoded by the gene estrogen receptor 1 (ESR1), which is widely studied to explore the gender difference in knee OA. Several polymorphisms in ESR1 [PvuII (rs2234693) and BtgI (rs2228480)] were confirmed as the risk factors of OA. However, the evidence of the last widely investigated polymorphism, ESR1 Xbal (rs9340799), is still insufficient for concluding its effect on knee OA. (2) Objective: This study proposed a case–control study to investigate the association between ESR1 Xbal and knee OA. Moreover, a meta-analysis and trial sequential analysis (TSA) were conducted to enlarge the sample size for obtaining a conclusive evidence. (3) Methods: In total, 497 knee OA cases and 473 healthy controls were recruited between March 2015 and July 2018. The Kellgren–Lawrence grading system was used to identify the knee OA cases. To improve the evidence level of our study, we conducted a meta-analysis including the related studies published up until December 2018 from PubMed, Embase, and previous meta-analysis. The results are expressed as odds ratios (ORs) with corresponding 95% confidence intervals (CI) for evaluating the effect of this polymorphism on knee OA risk. TSA was used to estimate the sample sizes required in this issue. (4) Results: We found non-significant association between the G allele and knee OA [Crude-OR: 0.97 (95% CI: 0.78–1.20) and adjusted-OR: 0.90 (95% CI: 0.71–1.15) in allele model] in the present case–control study, and the analysis of other genetic models showed a similar trend. After including six published studies and our case–control studies, the current evidence with 3174 Asians showed the conclusively null association between ESR1 XbaI and knee OA [OR: 0.78 (95% CI: 0.59–1.04)] with a high heterogeneity (I2: 78%). The result of Caucasians also concluded the null association [OR: 1.05 (95% CI: 0.56–1.95), I2: 87%]. (5) Conclusions: The association between ESR1 XbaI and knee OA was not similar with other polymorphisms in ESR1, which is not a causal relationship. This study integrated all current evidence to elaborate this conclusion for suggesting no necessity of future studies.

Association of the UCP polymorphisms with susceptibility to obesity: case-control study and meta-analysis

2014 ◽  
Author(s):  
Bianca Souza ◽  
Leticia Brondani ◽  
Tais Assmann ◽  
Ana Paula Boucas ◽  
Andrea Carla Bauer ◽  
...  
Keyword(s):  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Control Study

scholarly journals Case–Control Study and Meta-Analysis of the Association Between LIPG rs9958947 SNP and Stroke Risk

2021 ◽  
Author(s):  
Kok Yeow Phneh ◽  
Eric Tzyy Jiann Chong ◽  
Syahiskandar Sybil Shah ◽  
Yuen Kang Chia ◽  
Dayang Maryama Bte Awang Daud ◽  
...  
Keyword(s):  
Stroke Risk ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Control Study
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