scholarly journals TP53 , p14 ARF , p16 INK4a and H-ras gene molecular analysis in intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses

2003 ◽  
Vol 105 (2) ◽  
pp. 196-203 ◽  
Author(s):  
Federica Perrone ◽  
Maria Oggionni ◽  
Sarah Birindelli ◽  
Simona Suardi ◽  
Silvia Tabano ◽  
...  
1990 ◽  
Vol 76 (3) ◽  
pp. 250-254 ◽  
Author(s):  
José I. López ◽  
Manuel Nevado ◽  
Beatriz Eizaguirre ◽  
Agustin Pérez

Head & Neck ◽  
2006 ◽  
Vol 28 (10) ◽  
pp. 909-915 ◽  
Author(s):  
Milo Frattini ◽  
Federica Perrone ◽  
Simona Suardi ◽  
Debora Balestra ◽  
Stefano Caramuta ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Tatiana M. Villatoro ◽  
Stacey K. Mardekian

Sinonasal non-intestinal-type adenocarcinoma (non-ITAC) is a rare, morphologically diverse neoplasm of the head and neck. Squamoid morular metaplasia has recently been reported as an occasional finding in non-ITAC. Interestingly, these squamoid morules often show aberrant expression of CDX2 as well as nuclear expression of β-catenin, similar to other tumors that show this type of metaplasia, but the underlying mechanism responsible for this finding is not completely understood. We present two cases of low-grade non-ITAC with squamoid morules coexpressing CDX2 and nuclear β-catenin by immunohistochemistry, both of which were found to harbor a mutation in CTNNB1, the gene encoding β-catenin. This finding provides support that an alteration in the β-catenin pathway, including mutations in the β-catenin gene itself, is responsible for this recently described morphologic phenomenon in non-ITAC.


2016 ◽  
Vol 41 (11) ◽  
pp. 888-889 ◽  
Author(s):  
Zhanli Fu ◽  
Jin Zhang ◽  
Meng Liu ◽  
Ziao Li ◽  
Qian Li

Toukeibu Gan ◽  
2019 ◽  
Vol 45 (3) ◽  
pp. 337-341
Author(s):  
Kazuki Nakamura ◽  
Takenori Ogawa ◽  
Ayako Nakanome ◽  
Akira Ohkoshi ◽  
Eiichi Ishida ◽  
...  

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