Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas

2002 ◽  
Vol 102 (3) ◽  
pp. 220-224 ◽  
Author(s):  
Masahiro Ohta ◽  
Yasuhiko Kitadai ◽  
Shinji Tanaka ◽  
Masaharu Yoshihara ◽  
Wataru Yasui ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Macrophage Infiltration ◽  
Tumor Vascularity ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein ◽  
Esophageal Squamous Cell Carcinomas

scholarly journals Monocyte Chemoattractant Protein-1 Deficiency Fails to Restrain Macrophage Infiltration Into Adipose Tissue

Diabetes ◽  
2008 ◽  
Vol 57 (5) ◽  
pp. 1254-1261 ◽  
Author(s):  
E. A. Kirk ◽  
Z. K. Sagawa ◽  
T. O. McDonald ◽  
K. D. O'Brien ◽  
J. W. Heinecke
Keyword(s):  
Adipose Tissue ◽  
Macrophage Infiltration ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein

scholarly journals Monocyte chemoattractant protein-1 and macrophage infiltration in hypertensive kidney injury

2000 ◽  
Vol 58 (6) ◽  
pp. 2408-2419 ◽  
Author(s):  
Karl F. Hilgers ◽  
Andrea Hartner ◽  
Markus Porst ◽  
Monika Mai ◽  
Michael Wittmann ◽  
...  
Keyword(s):  
Kidney Injury ◽  
Macrophage Infiltration ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein

Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas

1997 ◽  
Vol 93 (5) ◽  
pp. 518-527 ◽  
Author(s):  
S. Y. Leung ◽  
Maria Pik Wong ◽  
Lap Ping Chung ◽  
Annie Shuk Yee Chan ◽  
Siu Tsan Yuen
Keyword(s):  
Macrophage Infiltration ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein

Expression of monocyte chemoattractant protein-1 in meningioma

1995 ◽  
Vol 82 (5) ◽  
pp. 874-878 ◽  
Author(s):  
Kyoichi Sato ◽  
Jun-Ichi Kuratsu ◽  
Hideo Takeshima ◽  
Teizo Yoshimura ◽  
Yukitaka Ushio
Keyword(s):  
Culture Fluid ◽  
Glioma Cell Line ◽  
Macrophage Infiltration ◽  
Content Type ◽  
Monocyte Chemoattractant Protein 1 ◽  
Messenger Ribonucleic Acid ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein ◽  
Perifocal Edema ◽  
Fine Print

✓ Monocyte chemoattractant protein-1 (MCP-1), purified from glioma cell line (U-105MG) culture fluid, attracts monocytes but not neutrophils. Macrophage accumulation is one of the pathological features of meningioma. To investigate the mechanism of macrophage infiltration into meningioma, the expression and localization of MCP-1 in 16 cases of meningioma were studied using Northern blot analysis and immunohistochemistry. Seven of 16 meningiomas expressed MCP-1 messenger ribonucleic acid and protein, and some degree of macrophage infiltration was seen in all 16 meningiomas. There was a relationship between MCP-1 expression and the degree of macrophage infiltration; MCP-1 was strongly expressed in meningiomas with a high degree of macrophage infiltration. Sometimes the meningioma was accompanied by perifocal edema; a correlation between macrophage infiltration into brain tumors and perifocal edema has already been reported. It was found that the degree of MCP-1 expression is not correlated with the extent of perifocal edema. The authors' findings suggest that MCP-1 plays an important role in macrophage infiltration into meningioma.

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