Dysregulation of phosphatidylinositol 3-kinase and downstream effectors in human breast cancer

Baljinder Salh; Anthony Marotta; Ravenska Wagey; Mohamed Sayed; Steven Pelech

doi:10.1002/ijc.10147

Dysregulation of phosphatidylinositol 3-kinase and downstream effectors in human breast cancer

International Journal of Cancer ◽

10.1002/ijc.10147 ◽

2002 ◽

Vol 98 (1) ◽

pp. 148-154 ◽

Cited By ~ 47

Author(s):

Baljinder Salh ◽

Anthony Marotta ◽

Ravenska Wagey ◽

Mohamed Sayed ◽

Steven Pelech

Keyword(s):

Breast Cancer ◽

Human Breast Cancer ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Downstream Effectors ◽

Phosphatidylinositol 3

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Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells

Cell Death and Disease ◽

10.1038/cddis.2012.179 ◽

2012 ◽

Vol 3 (12) ◽

pp. e440-e440 ◽

Cited By ~ 5

Author(s):

V Folgiero ◽

S E Di Carlo ◽

G Bon ◽

E P Spugnini ◽

A Di Benedetto ◽

...

Keyword(s):

Breast Cancer ◽

Antitumor Activity ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Catalytic Subunit ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Phosphatidylinositol 3

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Phosphatidylinositol 3-kinase (PI3Kα)/AKT axis blockade with taselisib or ipatasertib enhances the efficacy of anti-microtubule drugs in human breast cancer cells

Oncotarget ◽

10.18632/oncotarget.20385 ◽

2017 ◽

Vol 8 (44) ◽

pp. 76479-76491 ◽

Cited By ~ 14

Author(s):

Floriana Morgillo ◽

Carminia Maria Della Corte ◽

Anna Diana ◽

Concetta di Mauro ◽

Vincenza Ciaramella ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Phosphatidylinositol 3

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Inhibition of the phosphatidylinositol 3-kinase/Akt pathway sensitizes MDA-MB468 human breast cancer cells to cerulenin-induced apoptosis

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-05-0049 ◽

2006 ◽

Vol 5 (3) ◽

pp. 494-501 ◽

Cited By ~ 40

Author(s):

Xuesong Liu ◽

Yan Shi ◽

Vincent L. Giranda ◽

Yan Luo

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Akt Pathway ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Induced Apoptosis ◽

Phosphatidylinositol 3

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ZSTK474, a specific class I phosphatidylinositol 3-kinase inhibitor, induces G1 arrest and autophagy in human breast cancer MCF-7 cells

Oncotarget ◽

10.18632/oncotarget.7658 ◽

2016 ◽

Vol 7 (15) ◽

pp. 19897-19909 ◽

Cited By ~ 22

Author(s):

Yaochen Wang ◽

Jing Liu ◽

Yuling Qiu ◽

Meihua Jin ◽

Xi Chen ◽

...

Keyword(s):

Breast Cancer ◽

Human Breast Cancer ◽

Kinase Inhibitor ◽

Class I ◽

G1 Arrest ◽

Specific Class ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Mcf 7 ◽

Phosphatidylinositol 3

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Phosphatidylinositol 3-kinase (PI3Kα)/AKT axis blockade with taselisib or ipatasertib enhances the efficacy of anti-microtubule drugs in human breast cancer cells

Annals of Oncology ◽

10.1093/annonc/mdx361.015 ◽

2017 ◽

Vol 28 ◽

pp. v5

Author(s):

A. Diana ◽

F. Morgillo ◽

C.M. Della Corte ◽

C. Di Mauro ◽

V. Ciaramella ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Phosphatidylinositol 3

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A novel imidazopyridine analogue as a phosphatidylinositol 3-kinase inhibitor against human breast cancer

Cancer Letters ◽

10.1016/j.canlet.2011.12.001 ◽

2012 ◽

Vol 318 (1) ◽

pp. 68-75 ◽

Cited By ~ 11

Author(s):

Hyunseung Lee ◽

Guang-Yong Li ◽

Yujeong Jeong ◽

Kyung Hee Jung ◽

Ju-Hee Lee ◽

...

Keyword(s):

Breast Cancer ◽

Human Breast Cancer ◽

Kinase Inhibitor ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Phosphatidylinositol 3

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Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor–positive human breast cancer

Journal of Clinical Investigation ◽

10.1172/jci41680 ◽

2010 ◽

Vol 120 (7) ◽

pp. 2406-2413 ◽

Cited By ~ 313

Author(s):

Todd W. Miller ◽

Bryan T. Hennessy ◽

Ana M. González-Angulo ◽

Emily M. Fox ◽

Gordon B. Mills ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Human Breast Cancer ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Hormone Dependence ◽

Estrogen Receptor Positive ◽

Phosphatidylinositol 3

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Down-Regulation of Phosphatidylinositol 3′-Kinase/AKT/Molecular Target of Rapamycin Metabolic Pathway by Primary Letrozole-Based Therapy in Human Breast Cancer

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-1046 ◽

2008 ◽

Vol 14 (9) ◽

pp. 2673-2680 ◽

Cited By ~ 48

Author(s):

Daniele Generali ◽

Stephen B. Fox ◽

Maria Pia Brizzi ◽

Giovanni Allevi ◽

Simone Bonardi ◽

...

Keyword(s):

Breast Cancer ◽

Metabolic Pathway ◽

Human Breast Cancer ◽

Molecular Target ◽

Target Of Rapamycin ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Down Regulation ◽

Phosphatidylinositol 3

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Angiotensin II suppresses adriamycin-induced apoptosis through activation of phosphatidylinositol 3-kinase/Akt signaling in human breast cancer cells

Acta Biochimica et Biophysica Sinica ◽

10.1111/j.1745-7270.2008.00402.x ◽

2008 ◽

Vol 40 (4) ◽

pp. 304-310 ◽

Cited By ~ 17

Author(s):

Yanbin Zhao ◽

Xuesong Chen ◽

Li Cai ◽

Yanmei Yang ◽

Guangjie Sui ◽

...

Keyword(s):

Breast Cancer ◽

Angiotensin Ii ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Akt Signaling ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Induced Apoptosis

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Phosphatidylinositol 3-Kinase and NF-κB Regulate Motility of Invasive MDA-MB-231 Human Breast Cancer Cells by the Secretion of Urokinase-type Plasminogen Activator

Journal of Biological Chemistry ◽

10.1074/jbc.m109579200 ◽

2001 ◽

Vol 277 (5) ◽

pp. 3150-3157 ◽

Cited By ~ 100

Author(s):

Daniel Sliva ◽

Maria T. Rizzo ◽

Denis English

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Plasminogen Activator ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator

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