scholarly journals Successful introduction of milk after a negative double‐blind placebo‐controlled food challenge test is independent of the total dose and milk product used during the challenge test

2020 ◽  
Vol 8 (3) ◽  
pp. 292-298 ◽  
Author(s):  
Celine A. Ven ◽  
Irene Herpertz ◽  
Lidy Lente ◽  
Gerbrich N. Meulen ◽  
Arvid W. A. Kamps
Keyword(s):  
Total Dose ◽  
Challenge Test ◽  
Food Challenge ◽  
Milk Product ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Food Challenge Test

scholarly journals The Effect of Wheat Allergy on the Course of Atopic Eczema in Patients over 14 Years of Age

2011 ◽  
Vol 54 (4) ◽  
pp. 157-162 ◽  
Author(s):  
Jarmila Čelakovská ◽  
Květuše Ettlerová ◽  
Karel Ettler ◽  
Jaroslava Vaněčková ◽  
Josef Bukač
Keyword(s):  
Food Allergy ◽  
Wheat Flour ◽  
Atopic Eczema ◽  
Challenge Test ◽  
Food Challenge ◽  
Wheat Allergy ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Food Challenge Test

Few studies concerning the importance of wheat allergy affecting the course of atopic eczema in adolescents and adult patients exist. Aim: The evaluation if wheat allergy can deteriorate the course of atopic eczema. Follow-up of patients with confirmed food allergy to wheat. Method: Altogether 179 persons suffering from atopic eczema were included in the study: 51 men and 128 women entered the study with an average age of 26.2 (s.d. 9.5 years) Dermatological and allergological examinations were performed, including skin prick tests, atopy patch tests, and specific serum IgE for wheat, open exposure test and double-blind, placebo-controlled food challenge test with wheat flour. Results: Wheat allergy affecting the coures of atopic eczema was confirmed in eight patients (4.5%) out of 179 patients enrolled in this study by double-blind, placebo controlled food challenge test. The course of atopic eczema showed a positive trend in patients with confirmed food allergy at 3, 6, 9, 12 month follow-up (statistical evaluation with paired t-test) after the elimination of wheat flour. Conclusion: Wheat allergy may play an important role in the worsening of atopic eczema (acting as a triggering exacerbating factor) only in a minority of adolescents and adult patients (4.5% in our study). The diagnostic methods (skin prick test, specific IgE, atopy patch test, history) cannot be used as separated tests for the determination of food allergy to wheat in patients with atopic eczema.Open exposure tests and double-blind, placebo-controlled food challenge should be used for the confirmation of wheat allergy affecting the course of atopic eczema.

Allergy To Shrimp: A Double Blind, Placebo-controlled, Food Challenge Study And Allergens Implicated In Spain.

2009 ◽  
Vol 123 (2) ◽  
pp. S23-S23 ◽  
Author(s):  
S. Sanchez-Garcia ◽  
C. Gamez ◽  
E. Lopez ◽  
M.D. Ibañez ◽  
C. Escudero ◽  
...  
Keyword(s):  
Food Challenge ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Challenge Study

Double-blind, placebo-controlled food challenge with apple

Allergy ◽  
2001 ◽  
Vol 56 (2) ◽  
pp. 109-117 ◽  
Author(s):  
K. Skamstrup Hansen ◽  
H. Vestergaard ◽  
P. Stahl Skov ◽  
M. Sondergaard Khinchi ◽  
S. Vieths ◽  
...  
Keyword(s):  
Food Challenge ◽  
Double Blind ◽  
Double Blind Placebo

Nahrungsmittelprovokationen im Kindesalter ganz praktisch

2018 ◽  
Vol 44 (08/09) ◽  
pp. 360-365
Author(s):  
M. Ziegert ◽  
V. Trendelenburg
Keyword(s):  
Food Challenge ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Klinische Relevanz

ZusammenfassungIm Säuglings- und Kleinkindalter gehören IgE-vermittelte Nahrungsmittelallergien zu den häufigsten allergischen Erkrankungen. Insbesondere die orale Nahrungsmittelprovokation stellt hier einen Grundpfeiler einer fundierten Diagnostik dar. Der Goldstandard ist die doppelblinde, Placebo-kontrollierte Nahrungsmittelprovokation (DBPCFC; double-blind, placebo-controlled food challenge). Sie hilft, v. a. bei unklarer Anamnese, die klinische Relevanz einer Sensibilisierung gegen Nahrungsmittel zu überprüfen oder neu zu evaluieren. Im Säuglings- und Kleinkindalter ist eine genaue Diagnostik besonders relevant, um unnötig einschränkende Eliminationsdiäten zu vermeiden oder den Patienten bzw. deren Eltern hinsichtlich einer individuell angepassten spezifischen Ernährungstherapie zu beraten. Dieser Artikel beschreibt praktische Vorgehensweisen für die Durchführung oraler Nahrungsmittelprovokationen im Kindesalter mit Fokus auf die am häufigsten vorkommenden IgE-vermittelten Nahrungsmittelallergien (Kuhmilch, Hühnerei, Erdnuss).

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