scholarly journals Diagnostic Usefulness of the Serum-Specific IgE, the Skin Prick Test and the Atopy Patch Test Compared with That of the Oral Food Challenge Test

2010 ◽  
Vol 22 (4) ◽  
pp. 404 ◽  
Author(s):  
Bo Young Chung ◽  
Hye One Kim ◽  
Chun Wook Park ◽  
Cheol Heon Lee
Keyword(s):  
Skin Prick Test ◽  
Patch Test ◽  
Challenge Test ◽  
Food Challenge ◽  
Specific Ige ◽  
Oral Food Challenge ◽  
Atopy Patch Test ◽  
Prick Test ◽  
Diagnostic Usefulness ◽  
Food Challenge Test

Negative Atopy Patch Test and Negative Skin Prick Test Reduce the Need for Oral Food Challenge in Children with Atopic Dermatitis

2011 ◽  
Vol 24 (2) ◽  
pp. 107-112 ◽  
Author(s):  
Angela Peron ◽  
Rossana Tenconi ◽  
Maddalena Leone ◽  
Patrizia Macellaro ◽  
Elena Ceriani ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Skin Prick Test ◽  
Patch Test ◽  
Food Challenge ◽  
Oral Food Challenge ◽  
Atopy Patch Test ◽  
Prick Test ◽  
Negative Skin Prick Test

scholarly journals The Effect of Birch Pollen Immunotherapy on Apple and rMal d 1 Challenges in Adults with Apple Allergy

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 519 ◽  
Author(s):  
Johanna van der Valk ◽  
Birgit Nagl ◽  
Roy Gerth van Wljk ◽  
Barbara Bohle ◽  
Nicolette de Jong
Keyword(s):  
Skin Prick Test ◽  
Challenge Test ◽  
Birch Pollen ◽  
Food Challenge ◽  
Specific Ige ◽  
P Value ◽  
Double Blind ◽  
P Values ◽  
Prick Test ◽  
Bet V 1

Background: A proportion of patients allergic to birch pollen are also allergic to pit fruit. The objective of this study was to investigate the effect of immunotherapy with birch pollen on birch-pollen-related apple allergy. Method: Patients with birch pollen immunotherapy underwent a skin-prick test with birch pollen, apple and rMal d 1, global assessments and nasal challenges with birch pollen, open food challenge with apple and a double-blind, placebo-controlled test with rMal d 1 at the start of and during the immunotherapy. Measurements of specific IgE in response to Bet v 1 and rMal d 1 and IgG4 in response to Bet v 1 and rMal d 1 took place. Results: Six of eight patients demonstrated an improvement of nasal challenge test results and all patients improved on global assessment during the immunotherapy. The median oral dose of apple required to elicit a reaction increased but was not statistically significant. The patients showed a decrease in skin-prick test values in response to birch pollen (1.05 to 0.36), apple (0.78 to 0.25) and rMal d 1 (0.51 to 0.10) with p-values of 0.04, 0.03 and 0.06, respectively and a decrease of specific IgE in response to Bet v 1 (10.66 kU/L to 5.19 kU/L) and rMal d 1 (0.99 to 0.61 kU/L) with p-values of 0.01 and 0.05, respectively. Only the median specific IgG4 value to Bet v 1 increased from 0.05 to 1.85 mg/L (p-value of 0.02) and not to IgG4 rMal d 1 (0.07 to 0.08 kU/L). Conclusion: The beneficial effects of immunotherapy for birch pollen were accompanied by a limited effect on apple allergy.

scholarly journals Atopy patch test (APT) in the diagnosis of food allergy in children with atopic dermatitis

2012 ◽  
Vol 87 (5) ◽  
pp. 724-728 ◽  
Author(s):  
Soloni Afra Pires Levy ◽  
Sergio Duarte Dortas Junior ◽  
Andrea Huguenim Silva Pires ◽  
Augusto Tiaqui Abe ◽  
Solange Oliveira Rodrigues Valle ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Skin Prick Test ◽  
Patch Test ◽  
Late Phase ◽  
Specific Ige ◽  
Atopy Patch Test ◽  
Prick Test ◽  
Occlusion Time ◽  
Specificity And Sensitivity

BACKGROUND: Atopic Dermatitis is a chronic inflammatory skin disease. Food allergens are important in the pathogenesis in 1/3 of the cases. Several mechanisms are involved in the pathogenesis of Atopic Dermatitis. Immediate reactions are identified by both measurement of specific IgE and skin prick test. Atopy Patch Test seems to be relevant in the investigation of patients with suspected delayed-type reactions. OBJECTIVES: To evaluate the standardization of this method concerning allergen concentration, occlusion time and interpretation, and determine the specificity and sensitivity of the Atopy Patch Test according to the skin prick test and specific IgE levels in food allergy diagnosis in children with Atopic Dermatitis. METHODS: Seventy-two children, aged 2-12 years were selected and followed at the allergy clinic of the Hospital São Zacharias. Skin prick test, specific IgE and food Atopy Patch Test (cow's milk, egg, soy and wheat) were carried out. Three groups were submitted to the Atopy Patch Test: (1) Atopic Dermatitis with or without Rhinitis and Asthma; (2) Rhinitis and or Asthma without AD; (3) Healthy individuals. RESULTS: In group 1, 40% of the patients presented positive reactions. The longer the exposure time (48h and 72h), the higher the sensitivity. In group 2, the test was more specific than sensitive for all the extracts, with increased sensitivity the longer the time of exposure (72h). In group 3, 8.3% presented positive tests. CONCLUSION: APT evidenced a great diagnostic value in late-phase reactions to food, with high specificity. It showed to be a specific and reliable tool in comparison with the healthy group's results.

scholarly journals Specific IgE for Fag e 3 Predicts Oral Buckwheat Food Challenge Test Results and Anaphylaxis: A Pilot Study

2018 ◽  
Vol 176 (1) ◽  
pp. 8-14 ◽  
Author(s):  
Noriyuki Yanagida ◽  
Sakura Sato ◽  
Nobuyuki Maruyama ◽  
Kyohei Takahashi ◽  
Ken-ichi Nagakura ◽  
...  
Keyword(s):  
Pilot Study ◽  
Challenge Test ◽  
Food Challenge ◽  
Specific Ige ◽  
Test Results ◽  
Food Challenge Test
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