ALDH2 genotype-associated differences in the acute effects of alcohol on P300, psychomotor performance, and subjective response in healthy young Korean men: a double-blind placebo-controlled crossover study

2006 ◽  
Vol 21 (3) ◽  
pp. 159-166 ◽  
Author(s):  
Hee-Young Shin ◽  
Il-Seon Shin ◽  
Jin-Sang Yoon
Keyword(s):  
Crossover Study ◽  
Psychomotor Performance ◽  
Subjective Response ◽  
Acute Effects ◽  
Double Blind ◽  
Double Blind Placebo

Caffeine counteracts impairments in task-oriented psychomotor performance induced by chlorpheniramine: a double-blind placebo-controlled crossover study

2012 ◽  
Vol 27 (1) ◽  
pp. 62-70 ◽  
Author(s):  
Sung-Wan Kim ◽  
Kyung-Yeol Bae ◽  
Hee-Young Shin ◽  
Jae-Min Kim ◽  
Il-Seon Shin ◽  
...  
Keyword(s):  
Crossover Study ◽  
Psychomotor Performance ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Task Oriented

scholarly journals No Acute Effects of Cannabidiol on the Sleep-Wake Cycle of Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

2018 ◽  
Vol 9 ◽  
Author(s):  
Ila M. P. Linares ◽  
Francisco S. Guimaraes ◽  
Alan Eckeli ◽  
Ana C. S. Crippa ◽  
Antonio W. Zuardi ◽  
...  
Keyword(s):  
Crossover Study ◽  
Healthy Subjects ◽  
Acute Effects ◽  
Double Blind ◽  
Double Blind Placebo

Effect of Stevia on Glycemic and Insulin Responses in Obese Patients—A Randomized, Double-Blind, Placebo-Controlled Crossover Study

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 790-P
Author(s):  
PARINYA SAMAKKARNTHAI ◽  
MANAPORN PAYANUNDANA ◽  
NATTAPOL SATHAVARODOM ◽  
CHONPITI SIRIWAN ◽  
APUSSANEE BOONYAVARAKUL
Keyword(s):  
Crossover Study ◽  
Obese Patients ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Insulin Responses

scholarly journals Acute and Short-term Chronic Testosterone Fluctuation Effects on Glucose Homeostasis, Insulin Sensitivity, and Adiponectin: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

2014 ◽  
Vol 99 (6) ◽  
pp. E1088-E1096 ◽  
Author(s):  
Christian Høst ◽  
Lars C. Gormsen ◽  
David M. Hougaard ◽  
Jens S. Christiansen ◽  
Steen B. Pedersen ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Glucose Metabolism ◽  
Crossover Study ◽  
High Molecular Weight ◽  
Glucose Disposal ◽  
Short Term ◽  
High Molecular Weight Adiponectin ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Total Glucose

Context: Low levels of adiponectin and T in men have been shown to predict development of the metabolic syndrome, but the effects of T on glucose metabolism are incompletely understood and may be influenced either directly or indirectly through changes in body composition or in levels of adiponectin. Objective: The aim of the study was to test whether T exerts its effects on glucose metabolism directly or indirectly. Design, Setting, and Participants: In a randomized, double-blind, placebo-controlled, crossover study, 12 healthy young males were studied on four separate occasions. They received GnRH agonist treatment 1 month before 3 of 4 trial days to induce castrate levels of T. On trial days, T gel containing either high or low physiological T dose or placebo was applied to the body. On a fourth trial day, participants constituted their own eugonadal controls. Intervention: Each study comprised a 5-hour basal period and a 3-hour hyperinsulinemic euglycemic clamp. Main Outcome Measures: We measured the effect of acute T on peripheral glucose disposal, total adiponectin and subforms, and other indices of glucose metabolism. Results: Short-term hypogonadism was associated with increased high molecular weight adiponectin levels (P < .03) and increased oxidative glucose disposal (P = .03) but not total glucose disposal (P = .07). Acute T treatment was an independent suppressor of high molecular weight adiponectin levels (P = .04) but did not affect total glucose disposal (P = .17). Conclusions: These data show that T can act through putative fast nongenomic pathways to affect adiponectin levels in humans. The early hypogonadal state is characterized by a marked shift in fuel oxidation from lipids toward glucose, which may rely partly on buffering capabilities of adiponectin.

scholarly journals Acute effects of dapagliflozin on renal oxygenation and perfusion in type 1 diabetes with albuminuria: A randomised, double-blind, placebo-controlled crossover trial

2021 ◽  
pp. 100895
Author(s):  
Jens Christian Laursen ◽  
Niels Søndergaard-Heinrich ◽  
Joana Mendes Lopes de Melo ◽  
Bryan Haddock ◽  
Ida Kirstine Bull Rasmussen ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Crossover Trial ◽  
Acute Effects ◽  
Double Blind ◽  
Double Blind Placebo

The Development of Subsensitivity to Atropine Methylnitrate: A Double-blind, Placebo-controlled Crossover Study

1988 ◽  
Vol 138 (4) ◽  
pp. 771-774 ◽  
Author(s):  
Thurman R. Vaughan ◽  
Robert E. Bowen ◽  
David L. Goodman ◽  
Richard W. Weber ◽  
Harold S. Nelson
Keyword(s):  
Crossover Study ◽  
Double Blind ◽  
Double Blind Placebo
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