Cognitive effects of pregabalin in the treatment of long-term benzodiazepine-use and dependence

Panagiotis Oulis; Stamatina Kalogerakou; Eleni Anyfandi; George Konstantakopoulos; Vassiliki-Maria Papakosta; Vasilios Masdrakis; Eleftheria Tsaltas

doi:10.1002/hup.2391

Cognitive effects of pregabalin in the treatment of long-term benzodiazepine-use and dependence

Human Psychopharmacology Clinical and Experimental ◽

10.1002/hup.2391 ◽

2014 ◽

Vol 29 (3) ◽

pp. 224-229 ◽

Cited By ~ 6

Author(s):

Panagiotis Oulis ◽

Stamatina Kalogerakou ◽

Eleni Anyfandi ◽

George Konstantakopoulos ◽

Vassiliki-Maria Papakosta ◽

...

Keyword(s):

Cognitive Effects ◽

Benzodiazepine Use

Download Full-text

Cognitive effects of long-term benzodiazepine use in older adults

Human Psychopharmacology Clinical and Experimental ◽

10.1002/hup.453 ◽

2003 ◽

Vol 18 (1) ◽

pp. 51-57 ◽

Cited By ~ 44

Author(s):

Mary Pat McAndrews ◽

Rachel T. Weiss ◽

Paul Sandor ◽

Ann Taylor ◽

Peter L. Carlen ◽

...

Keyword(s):

Older Adults ◽

Cognitive Effects ◽

Benzodiazepine Use

Download Full-text

An evaluation of persisting cognitive effects after withdrawal from long-term benzodiazepine use

Journal of the International Neuropsychological Society ◽

10.1017/s1355617705050332 ◽

2005 ◽

Vol 11 (3) ◽

pp. 281-289 ◽

Cited By ~ 32

Author(s):

MELINDA J. BARKER ◽

KENNETH M. GREENWOOD ◽

MARTIN JACKSON ◽

SIMON F. CROWE

Keyword(s):

Verbal Memory ◽

Neuropsychological Tests ◽

Control Group ◽

Cognitive Effects ◽

Control Performance ◽

Nonverbal Memory ◽

Visuospatial Skills ◽

Benzodiazepine Use ◽

Anxiety Levels

Twenty participants with self-reported long-term benzodiazepine use (mean 108 months) who had previously withdrawn from medication (mean 42 months) were administered a battery of neuropsychological tests. Each long-term user was case matched for age, sex, and education to two control participants who reported never taking benzodiazepines (those with and those without anxiety). The results indicated that long-term benzodiazepine use may lead to impairments in the areas of verbal memory, motor control/performance, and nonverbal memory but not visuospatial skills and attention/concentration. The length of abstinence (> 6 months) indicates that these impairments persist well beyond cessation of benzodiazepine use. However, observed impairments in the area of nonverbal memory were not solely attributable to benzodiazepine use and may be influenced by the elevated anxiety levels present in both the case and the anxious control group. (JINS, 2005,11, 281–289.)

Download Full-text