Correlating disease-related mutations to their effect on protein stability: A large-scale analysis of the human proteome

2011 ◽  
Vol 32 (10) ◽  
pp. 1161-1170 ◽  
Author(s):  
Rita Casadio ◽  
Marco Vassura ◽  
Shalinee Tiwari ◽  
Piero Fariselli ◽  
Pier Luigi Martelli
Keyword(s):  
Protein Stability ◽  
Large Scale ◽  
Human Proteome ◽  
Scale Analysis ◽  
Large Scale Analysis

scholarly journals Large scale analysis of protein stability in OMIM disease related human protein variants

BMC Genomics ◽  
2016 ◽  
Vol 17 (S2) ◽  
Author(s):  
Pier Luigi Martelli ◽  
Piero Fariselli ◽  
Castrense Savojardo ◽  
Giulia Babbi ◽  
Francesco Aggazio ◽  
...  
Keyword(s):  
Protein Stability ◽  
Large Scale ◽  
Human Protein ◽  
Scale Analysis ◽  
Large Scale Analysis ◽  
Protein Variants

scholarly journals Advances in decomposing complex metabolite mixtures using substructure- and network-based computational metabolomics approaches

2021 ◽  
Author(s):  
Mehdi A. Beniddir ◽  
Kyo Bin Kang ◽  
Grégory Genta-Jouve ◽  
Florian Huber ◽  
Simon Rogers ◽  
...  
Keyword(s):  
Natural Product ◽  
Large Scale ◽  
Scale Analysis ◽  
Computational Tools ◽  
Natural Product Discovery ◽  
Large Scale Analysis ◽  
Metabolite Annotation

This review highlights the key computational tools and emerging strategies for metabolite annotation, and discusses how these advances will enable integrated large-scale analysis to accelerate natural product discovery.

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