Partial duplication atAZFcon the Y chromosome is a risk factor for impaired spermatogenesis in Han Chinese in Taiwan

2007 ◽  
Vol 28 (5) ◽  
pp. 486-494 ◽  
Author(s):  
Yi-Wen Lin ◽  
Lea Chia-Ling Hsu ◽  
Pao-Lin Kuo ◽  
William J. Huang ◽  
Han-Sun Chiang ◽  
...  
Keyword(s):  
Risk Factor ◽  
Y Chromosome ◽  
Han Chinese ◽  
Partial Duplication

The functional SNP rs4376531 in the ARHGEF gene is a risk factor for the atherothrombotic stroke in Han Chinese

2011 ◽  
Vol 59 (3) ◽  
pp. 408 ◽  
Author(s):  
Li He ◽  
Bo Zhang ◽  
Jian Guo ◽  
Xiang-Hua He ◽  
Yan-Ying Yin ◽  
...  
Keyword(s):  
Risk Factor ◽  
Han Chinese ◽  
Functional Snp

GLIS1rs797906: An Increased Risk Factor for Late-Onset Parkinson’s Disease in the Han Chinese Population

2012 ◽  
Vol 68 (2) ◽  
pp. 89-92 ◽  
Author(s):  
Wei Song ◽  
Yong Ping Chen ◽  
Rui Huang ◽  
Ke Chen ◽  
Ping Lei Pan ◽  
...  
Keyword(s):  
Risk Factor ◽  
Chinese Population ◽  
Late Onset ◽  
Han Chinese ◽  
Han Chinese Population ◽  
Increased Risk

scholarly journals A genetic risk factor for thrombophilia in a Han Chinese family

2017 ◽  
Vol 15 (4) ◽  
pp. 1668-1672 ◽  
Author(s):  
Guoping Sun ◽  
Yicong Jia ◽  
Jingye Meng ◽  
Minglin Ou ◽  
Peng Zhu ◽  
...  
Keyword(s):  
Risk Factor ◽  
Genetic Risk ◽  
Han Chinese ◽  
Genetic Risk Factor ◽  
Chinese Family

Homozygote C/C at rs12543318 was risk factor for non-syndromic cleft lip only from Western Han Chinese population

2018 ◽  
Vol 47 (6) ◽  
pp. 620-626
Author(s):  
Bi-He Zhang ◽  
Ning Huang ◽  
Jia-Yu Shi ◽  
Bing Shi ◽  
Zhong-Lin Jia
Keyword(s):  
Risk Factor ◽  
Chinese Population ◽  
Cleft Lip ◽  
Han Chinese ◽  
Han Chinese Population

scholarly journals Occurrence of Gonadoblastoma in Females with Turner Syndrome and Y Chromosome Material: A Population Study*

2000 ◽  
Vol 85 (9) ◽  
pp. 3199-3202 ◽  
Author(s):  
Claus Højbjerg Gravholt ◽  
Jens Fedder ◽  
Rune Weis Naeraa ◽  
Jørn Müller
Keyword(s):  
Risk Factor ◽  
Turner Syndrome ◽  
Y Chromosome ◽  
Carcinoma In Situ ◽  
Dna Analysis ◽  
Epidemiological Studies ◽  
Histopathological Evaluation ◽  
Primer Sets ◽  
Chromosome Material

Abstract The presence of Y chromosome material in patients with Turner syndrome is a risk factor for the development of gonadoblastoma. However, no cases with gonadoblastoma or other ovarian malignancies have been found in epidemiological studies of cancer, morbidity, or mortality in Turner syndrome. We examined 114 females with Turner syndrome for the presence of Y chromosome material by PCR. Initially, five different primer sets were used. Y Chromosome-positive individuals were further examined with an additional four primer sets. We found 14 (12.2%; 95% confidence interval, 6.9–19.7%) patients who had Y chromosome material. The karyotype in 7 of these patients did not suggest the presence of Y chromosome material. Seven of the patients had been ovariectomized before entering the study due to verified Y chromosome material, whereas three patients were operated upon after the DNA analysis. The histopathological evaluations showed that 1 of the 10 ovariectomized patients actually had a gonadoblastoma. The rest of the patients did not have gonadoblastoma or carcinoma in situ on histopathological evaluation. Three patients (age, >50 yr) positive for Y chromosome material chose not to have ovariectomy performed, and detailed ultrasonographies did not suggest the presence of gonadoblastoma. The frequency of Y chromosome material is high in Turner syndrome (12.2%), but the occurrence of gonadoblastoma among Y-positive patients seems to be low (7–10%), and the risk may have been overestimated in previous studies, perhaps due to problems with selection bias. This study emphasizes the need for prospective unbiased studies.

LRRK2 Gly2385Arg variant is a risk factor of Parkinson’s disease among Han-Chinese from mainland China

2008 ◽  
Vol 15 (3) ◽  
pp. 301-305 ◽  
Author(s):  
X.-K. An ◽  
R. Peng ◽  
T. Li ◽  
J.-M. Burgunder ◽  
Y. Wu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Risk Factor ◽  
Mainland China ◽  
Han Chinese

scholarly journals The association of Y chromosome haplogroups with spermatogenic failure in the Han Chinese

2007 ◽  
Vol 52 (8) ◽  
pp. 659-663 ◽  
Author(s):  
Chuncheng Lu ◽  
Feng Zhang ◽  
Yankai Xia ◽  
Bin Wu ◽  
Aihua Gu ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Han Chinese ◽  
Spermatogenic Failure

Ancient DNA evidence reveals that the Y chromosome haplogroup Q1a1 admixed into the Han Chinese 3,000 years ago

2014 ◽  
Vol 26 (6) ◽  
pp. 813-821 ◽  
Author(s):  
Yong-Bin Zhao ◽  
Ye Zhang ◽  
Hong-Jie Li ◽  
Ying-Qiu Cui ◽  
Hong Zhu ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Ancient Dna ◽  
Han Chinese ◽  
Dna Evidence

scholarly journals Y chromosome gr/gr deletions are a risk factor for low semen quality

2009 ◽  
Vol 24 (10) ◽  
pp. 2667-2673 ◽  
Author(s):  
L. Visser ◽  
G.H. Westerveld ◽  
C.M. Korver ◽  
S.K.M. van Daalen ◽  
S.E. Hovingh ◽  
...  
Keyword(s):  
Risk Factor ◽  
Y Chromosome ◽  
Semen Quality
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