3?-Amino-Modified Nucleotides Useful as Potent Chain Terminators for current DNA sequencing methods

1994 ◽  
Vol 77 (2) ◽  
pp. 586-596 ◽  
Author(s):  
Mathias K. Herrlein ◽  
Renate E. Konrad ◽  
Joachim W. Engels ◽  
Torsten Holietz ◽  
Dieter Cech
1994 ◽  
Vol 4 (16) ◽  
pp. 1975-1978 ◽  
Author(s):  
Konrad Faulstich ◽  
Mathias K. Herrlein ◽  
Siegfried Brandtner ◽  
Renate E. Konrad ◽  
Christian Griesinger ◽  
...  

1999 ◽  
Vol 82 (9) ◽  
pp. 1311-1323 ◽  
Author(s):  
Karen Stolze ◽  
Ulrich Koert ◽  
Sven Klingel ◽  
Gregor Sagner ◽  
Regina Wartbichler ◽  
...  

ChemInform ◽  
2010 ◽  
Vol 31 (2) ◽  
pp. no-no
Author(s):  
Karen Stolze ◽  
Ulrich Koert ◽  
Sven Klingel ◽  
Gregor Sagner ◽  
Regina Wartbichler ◽  
...  

1997 ◽  
Vol 16 (7-9) ◽  
pp. 1757-1760 ◽  
Author(s):  
Isabelle Rasolonjatovo ◽  
Catherine Guerreiro ◽  
Robert S. Sarfati

Author(s):  
S.A.C. Gould ◽  
B. Drake ◽  
C.B. Prater ◽  
A.L. Weisenhorn ◽  
S.M. Lindsay ◽  
...  

The atomic force microscope (AFM) is an instrument that can be used to image many samples of interest in biology and medicine. Images of polymerized amino acids, polyalanine and polyphenylalanine demonstrate the potential of the AFM for revealing the structure of molecules. Images of the protein fibrinogen which agree with TEM images demonstrate that the AFM can provide topographical data on larger molecules. Finally, images of DNA suggest the AFM may soon provide an easier and faster technique for DNA sequencing.The AFM consists of a microfabricated SiO2 triangular shaped cantilever with a diamond tip affixed at the elbow to act as a probe. The sample is mounted on a electronically driven piezoelectric crystal. It is then placed in contact with the tip and scanned. The topography of the surface causes minute deflections in the 100 μm long cantilever which are detected using an optical lever.


2001 ◽  
Vol 28 (10) ◽  
pp. 549-554
Author(s):  
Ryan N. Cole ◽  
Stewart W. West ◽  
Christine L. Terrell ◽  
Glenn D. Roberts ◽  
Iftikhar Ahmed
Keyword(s):  

2007 ◽  
Vol 8 (S1) ◽  
pp. S21-S21
Author(s):  
Elaine R. Mardis
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