The effect of body mass index on hippocampal morphology and memory performance in late childhood and adolescence

Hippocampus ◽  
2020 ◽  
Author(s):  
Kirsten M. Lynch ◽  
Kathleen A. Page ◽  
Yonggang Shi ◽  
Anny H. Xiang ◽  
Arthur W. Toga ◽  
...  
2015 ◽  
Vol 18 (5) ◽  
pp. 557-570 ◽  
Author(s):  
Aline Jelenkovic ◽  
Yoshie Yokoyama ◽  
Reijo Sund ◽  
Chika Honda ◽  
Leonie H Bogl ◽  
...  

A trend toward greater body size in dizygotic (DZ) than in monozygotic (MZ) twins has been suggested by some but not all studies, and this difference may also vary by age. We analyzed zygosity differences in mean values and variances of height and body mass index (BMI) among male and female twins from infancy to old age. Data were derived from an international database of 54 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins), and included 842,951 height and BMI measurements from twins aged 1 to 102 years. The results showed that DZ twins were consistently taller than MZ twins, with differences of up to 2.0 cm in childhood and adolescence and up to 0.9 cm in adulthood. Similarly, a greater mean BMI of up to 0.3 kg/m2 in childhood and adolescence and up to 0.2 kg/m2 in adulthood was observed in DZ twins, although the pattern was less consistent. DZ twins presented up to 1.7% greater height and 1.9% greater BMI than MZ twins; these percentage differences were largest in middle and late childhood and decreased with age in both sexes. The variance of height was similar in MZ and DZ twins at most ages. In contrast, the variance of BMI was significantly higher in DZ than in MZ twins, particularly in childhood. In conclusion, DZ twins were generally taller and had greater BMI than MZ twins, but the differences decreased with age in both sexes.


2001 ◽  
Vol 13 (3) ◽  
pp. 349-355 ◽  
Author(s):  
François Trudeau ◽  
Roy J. Shephard ◽  
François Arsenault ◽  
Louis Laurencelle

Thorax ◽  
2018 ◽  
Vol 73 (6) ◽  
pp. 538-545 ◽  
Author(s):  
Sandra Ekström ◽  
Jenny Hallberg ◽  
Inger Kull ◽  
Jennifer L P Protudjer ◽  
Per Thunqvist ◽  
...  

BackgroundFew large prospective studies have investigated the impact of body mass index (BMI) on lung function during childhood.MethodsUsing data collected between 2002 and 2013, we analysed associations between BMI status and lung function (assessed by spirometry) from 8 to 16 years, as well as cross-sectional associations with small airway function (impulse oscillometry) at 16 years in the BAMSE cohort (n=2889). At 16 years, cross-sectional associations with local and systemic inflammation were investigated by analysing FENO, blood eosinophils and neutrophils.ResultsOverweight and obesity at 8 years were associated with higher FVC, but lower FEV1/FVC ratio at 8 and 16 years. In boys, but not girls, obesity at 8 years was associated with a further reduction in FEV1/FVC between 8 and 16 years. In cross-sectional analyses, overweight and obesity were associated with higher frequency dependence of resistance (R5–20) and larger area under the reactance curve (AX0.5) at 16 years. Increased blood neutrophil counts were seen in overweight and obese girls, but not in boys. No association was found between BMI status and FENO. Persistent, but not transient, overweight/obesity between 8 and 16 years was associated with higher R5–20 and AX0.5 and lower FEV1/FVC (−2.8% (95% CI −4.1 to −1.2) in girls and −2.7% (95% CI −4.4 to −1.1) in boys) at 16 years, compared with persistent normal weight.ConclusionIn childhood and adolescence, overweight and obesity, particularly persistent overweight, were associated with evidence of airway obstruction, including the small airways.


2002 ◽  
Vol 76 (3) ◽  
pp. 653-658 ◽  
Author(s):  
Shumei Sun Guo ◽  
Wei Wu ◽  
William Cameron Chumlea ◽  
Alex F Roche

Author(s):  
I. Cotter ◽  
C. Healy ◽  
R. King ◽  
DR. Cotter ◽  
M. Cannon

Abstract Background. Abnormal body mass index (BMI) has been associated with development of psychopathology. This association in children is well documented, for both overweight and underweight children. However, the association between change in BMI and the development of psychopathology has been less investigated. Aim. To investigate the association between change in BMI between childhood and adolescence and psychopathology in adolescence. Methods. Data from the Growing Up in Ireland cohort were used. We investigated the ’98 cohort (also known as the child cohort) at age 9/13. BMI, defined using internationally recognised definitions as underweight, healthy or overweight, was used as the exposure, and abnormal Strength and Difficulties Questionnaire scores were used as the outcome. Logistic regression was undertaken for the analysis. All analyses were adjusted for confounders. Results. A change to overweight from healthy BMI was significantly associated with increased risk of psychopathology (adjusted OR 1.66; 95% CI 1.19–2.32). Both change from underweight to healthy (adjusted OR 0.12; 95% CI 0.03–0.43) or from overweight to healthy (adjusted OR 0.47; 95% CI 0.79–0.8) was associated with a significantly reduced risk of developing psychopathology. Discussion. As a child’s BMI returns to within the healthy range, their risk of adolescent psychopathology is reduced. Interventions to restore healthy BMI, in both underweight and overweight, children may reduce their risk of adolescent psychopathology.


2018 ◽  
Vol 33 (6) ◽  
pp. 703-794
Author(s):  
Z Mestre ◽  
J Osuna ◽  
Z Zlatar ◽  
S Appleton-Knapp ◽  
C Weirenga ◽  
...  

2013 ◽  
Vol 19 (6) ◽  
pp. 754-764 ◽  
Author(s):  
Jill M Holm-Denoma ◽  
April Smith ◽  
Peter M Lewinsohn ◽  
Jeremy W Pettit

2014 ◽  
Vol 39 (1) ◽  
pp. 52-60 ◽  
Author(s):  
D Petroff ◽  
K Kromeyer-Hauschild ◽  
S Wiegand ◽  
D l'Allemand-Jander ◽  
G Binder ◽  
...  

2017 ◽  
Vol 20 (C) ◽  
pp. 49
Author(s):  
Victoria Garcia ◽  
Santiago Curcio ◽  
Agustina Zinoveev ◽  
Gustavo Giachetto ◽  
Pedro Chiesa ◽  
...  

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