scholarly journals Medial temporal lobe projections to the retrosplenial cortex of the macaque monkey

Hippocampus ◽  
2012 ◽  
Vol 22 (9) ◽  
pp. 1883-1900 ◽  
Author(s):  
John P. Aggleton ◽  
Nicholas F. Wright ◽  
Seralynne D. Vann ◽  
Richard C. Saunders
Keyword(s):  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Macaque Monkey ◽  
Retrosplenial Cortex

scholarly journals Distinct Cortical Anatomy Linked to Subregions of the Medial Temporal Lobe Revealed by Intrinsic Functional Connectivity

2008 ◽  
Vol 100 (1) ◽  
pp. 129-139 ◽  
Author(s):  
Itamar Kahn ◽  
Jessica R. Andrews-Hanna ◽  
Justin L. Vincent ◽  
Abraham Z. Snyder ◽  
Randy L. Buckner
Keyword(s):  
Functional Connectivity ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Temporal Cortex ◽  
Memory System ◽  
Retrosplenial Cortex ◽  
The Body ◽  
Parallel Pathways ◽  
Ventral Medial Prefrontal Cortex ◽  
Adjacent Structures

The hippocampus and adjacent cortical structures in the medial temporal lobe (MTL) contribute to memory through interactions with distributed brain areas. Studies of monkey and rodent anatomy suggest that parallel pathways converge on distinct subregions of the MTL. To explore the cortical areas linked to subregions of the MTL in humans, we examined cortico-cortical and hippocampal-cortical correlations using high-resolution, functional connectivity analysis in 100 individuals. MTL seed regions extended along the anterior to posterior axis and included hippocampus and adjacent structures. Results revealed two separate brain pathways that correlated with distinct subregions within the MTL. The body of the hippocampus and posterior parahippocampal cortex correlated with lateral parietal cortex, regions along the posterior midline including posterior cingulate and retrosplenial cortex, and ventral medial prefrontal cortex. By contrast, anterior hippocampus and the perirhinal/entorhinal cortices correlated with distinct regions in the lateral temporal cortex extending into the temporal pole. The present results are largely consistent with known connectivity in the monkey and provide a novel task-independent dissociation of the parallel pathways supporting the MTL memory system in humans. The cortical pathways include regions that have undergone considerable areal expansion in humans, providing insight into how the MTL memory system has evolved to support a diverse array of cognitive domains.

scholarly journals Medial Prefrontal–Medial Temporal Theta Phase Coupling in Dynamic Spatial Imagery

2017 ◽  
Vol 29 (3) ◽  
pp. 507-519 ◽  
Author(s):  
Raphael Kaplan ◽  
Daniel Bush ◽  
James A. Bisby ◽  
Aidan J. Horner ◽  
Sofie S. Meyer ◽  
...  
Keyword(s):  
Working Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Theta Rhythm ◽  
Mental Simulation ◽  
Retrosplenial Cortex ◽  
Delay Period ◽  
Phase Coupling ◽  
Theta Phase ◽  
Dynamic Imagery

Hippocampal–medial prefrontal interactions are thought to play a crucial role in mental simulation. Notably, the frontal midline/medial pFC (mPFC) theta rhythm in humans has been linked to introspective thought and working memory. In parallel, theta rhythms have been proposed to coordinate processing in the medial temporal cortex, retrosplenial cortex (RSc), and parietal cortex during the movement of viewpoint in imagery, extending their association with physical movement in rodent models. Here, we used noninvasive whole-head MEG to investigate theta oscillatory power and phase-locking during the 18-sec postencoding delay period of a spatial working memory task, in which participants imagined previously learned object sequences either on a blank background (object maintenance), from a first-person viewpoint in a scene (static imagery), or moving along a path past the objects (dynamic imagery). We found increases in 4- to 7-Hz theta power in mPFC when comparing the delay period with a preencoding baseline. We then examined whether the mPFC theta rhythm was phase-coupled with ongoing theta oscillations elsewhere in the brain. The same mPFC region showed significantly higher theta phase coupling with the posterior medial temporal lobe/RSc for dynamic imagery versus either object maintenance or static imagery. mPFC theta phase coupling was not observed with any other brain region. These results implicate oscillatory coupling between mPFC and medial temporal lobe/RSc theta rhythms in the dynamic mental exploration of imagined scenes.

scholarly journals The retrosplenial cortex: A memory gateway between the cortical default mode network and the medial temporal lobe

2018 ◽  
Vol 39 (5) ◽  
pp. 2020-2034 ◽  
Author(s):  
Neda Kaboodvand ◽  
Lars Bäckman ◽  
Lars Nyberg ◽  
Alireza Salami
Keyword(s):  
Temporal Lobe ◽  
Default Mode Network ◽  
Medial Temporal Lobe ◽  
Retrosplenial Cortex ◽  
Default Mode

Early Distinctions between Self and Other, Focal and Global, Are Coded in the Medial Temporal Lobe

2016 ◽  
Author(s):  
James H. Austin
Keyword(s):  
Entorhinal Cortex ◽  
Temporal Lobe ◽  
Nobel Prize ◽  
Medial Temporal Lobe ◽  
Retrosplenial Cortex ◽  
Place Cells ◽  
Grid Cells ◽  
Self And Other ◽  
Landmark Location

This chapter reviews 2014 Nobel Prize-winning research on the hippocampus and parahippocampus. It considers place cells and grid cells and emphasizes that early primate studies had identified egocentric and allocentric responses in the hippocampus. It also notes that both direction codes and landmark location codes are represented in the retrosplenial cortex as well as in the entorhinal cortex.

scholarly journals Saccades phase-locked to alpha oscillations in the occipital and medial temporal lobe enhance memory encoding

2017 ◽  
Author(s):  
Tobias Staudigl ◽  
Elisabeth Hartl ◽  
Soheyl Noachtar ◽  
Christian F. Doeller ◽  
Ole Jensen
Keyword(s):  
Eye Movements ◽  
Temporal Lobe ◽  
Visual Information ◽  
Medial Temporal Lobe ◽  
Retrosplenial Cortex ◽  
Neural Oscillations ◽  
Memory Encoding ◽  
Alpha Oscillations ◽  
Memory Mapping ◽  
Efficient Sampling

AbstractEfficient sampling of visual information requires a coordination of eye movements and ongoing brain oscillations. Using intracranial and MEG recordings, we show that saccades are locked to the phase of visual alpha oscillations, and that this coordination supports mnemonic encoding of visual scenes. Furthermore, parahippocampal and retrosplenial cortex involvement in this coordination reflects effective vision-to-memory mapping, highlighting the importance of neural oscillations for the interaction between visual and memory domains.

scholarly journals Conserved fMRI and LFP Signals during New Associative Learning in the Human and Macaque Monkey Medial Temporal Lobe

Neuron ◽  
2012 ◽  
Vol 74 (4) ◽  
pp. 743-752 ◽  
Author(s):  
Eric L. Hargreaves ◽  
Aaron T. Mattfeld ◽  
Craig E.L. Stark ◽  
Wendy A. Suzuki
Keyword(s):  
Associative Learning ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Macaque Monkey

Children show adult-like hippocampal pattern separation for familiar but not novel events

2020 ◽  
Author(s):  
Susan L. Benear ◽  
Elizabeth A. Horwath ◽  
Emily Cowan ◽  
M. Catalina Camacho ◽  
Chi Ngo ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Developmental Change ◽  
Pattern Separation ◽  
Developmental Changes ◽  
Similarity Analysis ◽  
Separation Processes ◽  
Parahippocampal Cortex ◽  
Pattern Similarity

The medial temporal lobe (MTL) undergoes critical developmental change throughout childhood, which aligns with developmental changes in episodic memory. We used representational similarity analysis to compare neural pattern similarity for children and adults in hippocampus and parahippocampal cortex during naturalistic viewing of clips from the same movie or different movies. Some movies were more familiar to participants than others. Neural pattern similarity was generally lower for clips from the same movie, indicating that related content taxes pattern separation-like processes. However, children showed this effect only for movies with which they were familiar, whereas adults showed the effect consistently. These data suggest that children need more exposures to stimuli in order to show mature pattern separation processes.

Sign in / Sign up

Export Citation Format

Share Document