scholarly journals Low Serum Cholinesterase Identifies Patients With Worse Outcome and Increased Mortality After TIPS

2021 ◽  
Author(s):  
Lena Stockhoff ◽  
Theresa Muellner‐Bucsics ◽  
Antoaneta A. Markova ◽  
Marie Schultalbers ◽  
Simone A. Keimburg ◽  
...  
Keyword(s):  
Serum Cholinesterase ◽  
Low Serum

A LOW SERUM CHOLINESTERASE ACTIVITY INDICATES A HIGHER MORTALITY IN CRITICALLY ILL PEDIATRIC PATIENTS.

2006 ◽  
Vol 34 ◽  
pp. A129
Author(s):  
Christian Sitzwohl ◽  
Thomas Gamsjäger ◽  
Carmen Anderle ◽  
Christian Weinstabl ◽  
Stephan C Kettner
Keyword(s):  
Critically Ill ◽  
Pediatric Patients ◽  
Cholinesterase Activity ◽  
Serum Cholinesterase ◽  
Serum Cholinesterase Activity ◽  
Low Serum

32 LOW SERUM CHOLINESTERASE LEVELS-CAN DIFFERENTIATE BETWEEN WELL COMPENSATED AND DECOMPENSATED CIRRHOSIS

2012 ◽  
Vol 2 (1) ◽  
pp. S20
Author(s):  
J Ramachandran ◽  
KG Sajith ◽  
S Priya ◽  
AK Dutta ◽  
KA Balasubramanian
Keyword(s):  
Decompensated Cirrhosis ◽  
Serum Cholinesterase ◽  
Low Serum

Detection of Patients with Low Serum Cholinesterase Activity: Inadequacy of "Acholest" Method

1972 ◽  
Vol 18 (6) ◽  
pp. 565-566 ◽  
Author(s):  
Albert A Dietz ◽  
Herbert Rubinstein ◽  
Tina Lubrano
Keyword(s):  
High Risk ◽  
Screening Test ◽  
Cholinesterase Activity ◽  
Serum Cholinesterase ◽  
Preoperative Screening ◽  
Test Paper ◽  
Prolonged Apnea ◽  
Serum Cholinesterase Activity ◽  
Paper Method ◽  
Low Serum

Abstract The "Acholest" test-paper method for estimating serum cholinesterase activity has been suggested as a preoperative screening test for patients potentially liable to prolonged apnea after use of succinylcholine. The method was tested on selected sera from normal persons and from patients with various hereditary variants of serum cholinesterase and results were compared to those obtained with a standard quantitative assay. The Acholest method failed to detect 12 of 20 cases at high risk of prolonged apnea after succinylcholine. It cannot therefore be considered as a suitable screening procedure.

scholarly journals Genetic analysis of mutations in individuals with low serum cholinesterase activity.

1994 ◽  
Vol 38 (3) ◽  
pp. 201-208
Author(s):  
Masato Maekawa ◽  
Kayoko Sudo ◽  
Dilip Chandra Dey ◽  
Kazuo Kotani ◽  
Jinko Ishikawa ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
Cholinesterase Activity ◽  
Serum Cholinesterase ◽  
Serum Cholinesterase Activity ◽  
Low Serum

scholarly journals Determinants of pesticide exposure among workers in floriculture industry in rural Maharashtra

2019 ◽  
Vol 6 (12) ◽  
pp. 5230
Author(s):  
Ashlesha A. Dandekar ◽  
Swati S. Raje ◽  
Prajakta G. Kadale
Keyword(s):  
Pesticide Exposure ◽  
Serum Cholinesterase ◽  
Cluster Sampling ◽  
Cross Sectional ◽  
Protective Devices ◽  
Health Related ◽  
Allowable Error ◽  
Laboratory Investigations ◽  
Low Serum ◽  
Structured Questionnaire

Background: Pesticides are extensively used in floriculture where workers are mostly unskilled and may not have appropriate knowledge about safety. Acute accidents during spraying are reported, chronic exposure goes unnoticed. There are not many Indian studies regarding health risks and safety practices among floriculture workers in India. Hence this study to assess pesticide exposure, to find their determinants and suggest appropriate preventive measures.Methods: Study was cross sectional in Floriculture Park, Talegaon (D), Pune, Maharashtra, India using cluster sampling from February 2018 to July 2019. Prevalence of morbidities being 63% sample size was calculated as 111 (allowable error 15%). Socio-demographic, work and health related variables were recorded using a pretested structured questionnaire. Clinical examination and laboratory investigations were done by medical experts.Results: A total of 118 workers participated. Only half (51.2%) were using personal protective devices. None were following reentry guidelines. 13.3% males and 4.1% females had low serum cholinesterase level which is a biomarker of pesticide exposure. Sprayers had significantly high risk of low serum cholinesterase levels (OR=3.31) as compared to others. With exposed subjects which included both sprayers as well as polyhouse workers the association increased with OR=4.27. However association was not significant when working in polyhouse alone was considered as a risk factor (OR=1.256).Conclusions: Presence of exposure was the only factor that had a statistically significant association with low Serum Cholinesterase levels. Safe occupational practices like use of personal protective devices, rotation of exposed workers, monitoring of serum cholinesterase levels and health education of workers should be undertaken.

Fibronexus-Like Adhesion Sites are Present at the Invasive Zones of Human Epidermoid Carcinomas

1982 ◽  
Vol 40 ◽  
pp. 106-109
Author(s):  
Irwin I. Singer
Keyword(s):  
Cell Cycle ◽  
Serum Concentration ◽  
Substrate Binding ◽  
High Serum ◽  
Adhesion Sites ◽  
Substrate Adhesion ◽  
Focal Contacts ◽  
Adhesion Complex ◽  
Low Serum

Our previous results indicate that two types of fibronectin-cytoskeletal associations may be formed at the fibroblast surface: dorsal matrixbinding fibronexuses generated in high serum (5% FBS) cultures, and ventral substrate-adhering units formed in low serum (0.3% FBS) cultures. The substrate-adhering fibronexus consists of at least vinculin (VN) and actin in its cytoplasmic leg, and fibronectin (FN) as one of its major extracellular components. This substrate-adhesion complex is localized in focal contacts, the sites of closest substratum approach visualized with interference reflection microscopy, which appear to be the major points of cell-tosubstrate adhesion. In fibroblasts, the latter substrate-binding complex is characteristic of cultures that are arrested at the G1 phase of the cell cycle due to the low serum concentration in their medium. These arrested fibroblasts are very well spread, flattened, and immobile.

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