scholarly journals Genetic analysis of mutations in individuals with low serum cholinesterase activity.

1994 ◽  
Vol 38 (3) ◽  
pp. 201-208
Author(s):  
Masato Maekawa ◽  
Kayoko Sudo ◽  
Dilip Chandra Dey ◽  
Kazuo Kotani ◽  
Jinko Ishikawa ◽  
...  
2006 ◽  
Vol 34 ◽  
pp. A129
Author(s):  
Christian Sitzwohl ◽  
Thomas Gamsjäger ◽  
Carmen Anderle ◽  
Christian Weinstabl ◽  
Stephan C Kettner

1972 ◽  
Vol 18 (6) ◽  
pp. 565-566 ◽  
Author(s):  
Albert A Dietz ◽  
Herbert Rubinstein ◽  
Tina Lubrano

Abstract The "Acholest" test-paper method for estimating serum cholinesterase activity has been suggested as a preoperative screening test for patients potentially liable to prolonged apnea after use of succinylcholine. The method was tested on selected sera from normal persons and from patients with various hereditary variants of serum cholinesterase and results were compared to those obtained with a standard quantitative assay. The Acholest method failed to detect 12 of 20 cases at high risk of prolonged apnea after succinylcholine. It cannot therefore be considered as a suitable screening procedure.


1987 ◽  
Vol 164 (2) ◽  
pp. 241-242 ◽  
Author(s):  
Masato Maekawa ◽  
Kayoko Sudo ◽  
Takashi Kanno

1984 ◽  
Vol 104 (4) ◽  
pp. 406-408
Author(s):  
KAZUNORI KITAMURA ◽  
KAZUNORI KATAYAMA ◽  
MASAWO KAKEMI ◽  
TAMOTSU KOIZUMI

1972 ◽  
Vol 18 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Philip J Garry ◽  
George M Owen ◽  
A Harold Lubin

Abstract We describe a useful technique to identify "fluoride-resistant" serum cholinesterase variants (E1uE1f and E1fE1f) by using the method of Garry to detect "atypical" variants and to measure serum cholinesterase activity [Clin. Chem. 17, 192 (1971)]. With butyrylthiocholine as substrate, sodium fluoride is used as a differential inhibitor in both Tris and phosphate buffer systems (50 mmol/liter, pH 7.4, 25°C). Fluoride inhibition values are plotted on two-dimensional graph paper, Tris plus sodium fluoride vs. phosphate plus sodium fluoride. Inhibition values for the "fluoride-resistant" and "atypical" variants are located in specific quadrants, which permits unequivocal identification of each variant. Examination of 836 Caucasian preschool children revealed a gene frequency of 0.0066 for the "fluoride" variant. No "fluoride-resistant" variants were found in 168 Negro preschool children examined.


1966 ◽  
Vol 12 (1) ◽  
pp. 25-27 ◽  
Author(s):  
A A Dietz ◽  
H M Rubinstein ◽  
T Lubrano

Abstract Serum cholinesterase activity was found to be normal in persons with analbuminemia. This finding disproves previous speculations that there is some intimate connection between the hepatic biosynthesis of albumin and serum cholinesterase.


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