Mutations in nonstructural protein 5A gene and response to interferon in hepatitis C virus genotype 2 infection

Takeshi Murakami; Nobuyuki Enomoto; Masayuki Kurosaki; Namiki Izumi; Fumiaki Marumo; Chifumi Sato

doi:10.1002/hep.510300405

Mutations in nonstructural protein 5A gene and response to interferon in hepatitis C virus genotype 2 infection

Hepatology ◽

10.1002/hep.510300405 ◽

1999 ◽

Vol 30 (4) ◽

pp. 1045-1053 ◽

Cited By ~ 55

Author(s):

Takeshi Murakami ◽

Nobuyuki Enomoto ◽

Masayuki Kurosaki ◽

Namiki Izumi ◽

Fumiaki Marumo ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Nonstructural Protein ◽

Virus Genotype ◽

Genotype 2 ◽

Nonstructural Protein 5A

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Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders

Hepatology ◽

10.1002/hep.24724 ◽

2012 ◽

Vol 55 (3) ◽

pp. 742-748 ◽

Cited By ~ 266

Author(s):

Kazuaki Chayama ◽

Shoichi Takahashi ◽

Joji Toyota ◽

Yoshiyasu Karino ◽

Kenji Ikeda ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Protease Inhibitor ◽

Nonstructural Protein ◽

Dual Therapy ◽

Virus Genotype ◽

Genotype 1B ◽

Nonstructural Protein 3 ◽

Nonstructural Protein 5A

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Number and Position of Mutations in the Interferon (IFN) Sensitivity–Determining Region of the Gene for Nonstructural Protein 5A Correlate with IFN Efficacy in Hepatitis C Virus Genotype 1b Infection

The Journal of Infectious Diseases ◽

10.1086/319674 ◽

2001 ◽

Vol 183 (8) ◽

pp. 1195-1203 ◽

Cited By ~ 49

Author(s):

Hideki Watanabe ◽

Nobuyuki Enomoto ◽

Kazuyoshi Nagayama ◽

Namiki Izumi ◽

Fumiaki Marumo ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Nonstructural Protein ◽

Virus Genotype ◽

Genotype 1B ◽

Nonstructural Protein 5A

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Highly efficient infectious cell culture of three hepatitis C virus genotype 2b strains and sensitivity to lead protease, nonstructural protein 5A, and polymerase inhibitors

Hepatology ◽

10.1002/hep.26660 ◽

2013 ◽

Vol 59 (2) ◽

pp. 395-407 ◽

Cited By ~ 46

Author(s):

Santseharay Ramirez ◽

Yi-Ping Li ◽

Sanne B. Jensen ◽

Jannie Pedersen ◽

Judith M. Gottwein ◽

...

Keyword(s):

Cell Culture ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Nonstructural Protein ◽

Virus Genotype ◽

Highly Efficient ◽

Polymerase Inhibitors ◽

Nonstructural Protein 5A

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Multiple ascending dose study of BMS-790052, a nonstructural protein 5A replication complex inhibitor, in patients infected with hepatitis C virus genotype 1

Hepatology ◽

10.1002/hep.24609 ◽

2011 ◽

Vol 54 (6) ◽

pp. 1956-1965 ◽

Cited By ~ 138

Author(s):

Richard E. Nettles ◽

Min Gao ◽

Marc Bifano ◽

Ellen Chung ◽

Anna Persson ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Nonstructural Protein ◽

Genotype 1 ◽

Virus Genotype ◽

Replication Complex ◽

Dose Study ◽

Nonstructural Protein 5A

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Nonstructural protein 5A/P32 deletion after failure of ledipasvir/sofosbuvir in hepatitis C virus genotype 1b infection

Hepatology ◽

10.1002/hep.29836 ◽

2018 ◽

Vol 68 (1) ◽

pp. 380-383 ◽

Cited By ~ 14

Author(s):

Akira Doi ◽

Hayato Hikita ◽

Ryotaro Sakamori ◽

Yuki Tahata ◽

Yugo Kai ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Nonstructural Protein ◽

Virus Genotype ◽

Genotype 1B ◽

Nonstructural Protein 5A

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P.172 Functional comparison of the antagonism of hepatitis C virus genotype 1b and 2a nonstructural protein 5a to interferon antiviral activity

Journal of Clinical Virology ◽

10.1016/s1386-6532(06)80352-5 ◽

2006 ◽

Vol 36 ◽

pp. S114

Author(s):

Y. Tsai ◽

L. Hwang

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Antiviral Activity ◽

Nonstructural Protein ◽

Virus Genotype ◽

Genotype 1B ◽

Nonstructural Protein 5A

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Faculty Opinions recommendation of Efficacy of sofosbuvir plus ribavirin with or without peginterferon-alfa in patients with hepatitis C virus genotype 3 infection and treatment-experienced patients with cirrhosis and hepatitis C virus genotype 2 infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725702749.793515296 ◽

2016 ◽

Author(s):

Adriaan van der Meer

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Genotype 3 ◽

Virus Genotype ◽

Genotype 2 ◽

Peginterferon Alfa

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The effectiveness and safety of sofosbuvir‐ledipasvir for patients with hepatitis C virus genotype 2 infection

Advances in Digestive Medicine ◽

10.1002/aid2.13258 ◽

2021 ◽

Author(s):

Po‐Yueh Chen ◽

Hsin‐Yi Yang ◽

Chu‐Kuang Chou ◽

Li‐Jen Chang ◽

Ming‐Tse Hsu ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Virus Genotype ◽

Genotype 2

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Role for TBC1D20 and Rab1 in Hepatitis C Virus Replication via Interaction with Lipid Droplet-Bound Nonstructural Protein 5A

Journal of Virology ◽

10.1128/jvi.00496-12 ◽

2012 ◽

Vol 86 (12) ◽

pp. 6491-6502 ◽

Cited By ~ 29

Author(s):

I. Nevo-Yassaf ◽

Y. Yaffe ◽

M. Asher ◽

O. Ravid ◽

S. Eizenberg ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Virus Replication ◽

Lipid Droplet ◽

Nonstructural Protein ◽

Nonstructural Protein 5A

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Mechanism of Zinc Ejection by Disulfiram in Nonstructural Protein 5A

Physical Chemistry Chemical Physics ◽

10.1039/d0cp06360f ◽

2021 ◽

Author(s):

Ashfaq Ur Rehman ◽

Guodong Zheng ◽

Bozitao Zhong ◽

Duan Ni ◽

Jia-Yi Li ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Nonstructural Protein ◽

Structural Protein ◽

Positive Strand ◽

Positive Strand Rna ◽

Nonstructural Protein 5A

Hepatitis C virus (HCV) is a notorious member of the enveloped, positive-strand RNA flavivirus family. Non-structural protein 5A (NS5A) plays a key role in HCV replication and assembly. NS5A is...

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