scholarly journals Muscle Alterations Are Associated With Minimal and Overt Hepatic Encephalopathy in Patients With Liver Cirrhosis

Hepatology ◽  
2019 ◽  
Vol 70 (5) ◽  
pp. 1704-1713 ◽  
Author(s):  
Silvia Nardelli ◽  
Barbara Lattanzi ◽  
Manuela Merli ◽  
Alessio Farcomeni ◽  
Stefania Gioia ◽  
...  
2018 ◽  
Vol 64 (5) ◽  
pp. 321-328 ◽  
Author(s):  
Kazuto TAJIRI ◽  
Yuka FUTSUKAICHI ◽  
Saito KOBAYASHI ◽  
Satoshi YASUMURA ◽  
Terumi TAKAHARA ◽  
...  

2016 ◽  
Vol 25 (17-18) ◽  
pp. 2559-2568 ◽  
Author(s):  
Patrizia Künzler-Heule ◽  
Sonja Beckmann ◽  
Romy Mahrer-Imhof ◽  
David Semela ◽  
Daniela Händler-Schuster

2019 ◽  
Vol 70 (1) ◽  
pp. e666-e667
Author(s):  
Silvia Nardelli ◽  
Barbara Lattanzi ◽  
Stefania Gioia ◽  
Lorenzo Ridola ◽  
Manuela Merli ◽  
...  

2019 ◽  
Vol 50 (10) ◽  
pp. 1112-1119
Author(s):  
Christian Labenz ◽  
Gerrit Toenges ◽  
Yvonne Huber ◽  
Michael Nagel ◽  
Jens U. Marquardt ◽  
...  

1995 ◽  
Vol 10 (4) ◽  
pp. 335-345 ◽  
Author(s):  
Piero Amodio ◽  
Piergiorgio Marchetti ◽  
Franco Del Piccolo ◽  
Giuseppe Sartori ◽  
Massimo Prior ◽  
...  

2018 ◽  
Vol 46 (9) ◽  
pp. 3596-3604 ◽  
Author(s):  
Xiaoxue Xia ◽  
Jiang Chen ◽  
Jiayun Xia ◽  
Bin Wang ◽  
Hua Liu ◽  
...  

Objective This study was performed to investigate the role of probiotics ( Clostridium butyricum combined with Bifidobacterium infantis) in the treatment of minimal hepatic encephalopathy (MHE) in patients with hepatitis B virus (HBV)-induced liver cirrhosis. Methods Sixty-seven consecutive patients with HBV-induced cirrhosis without overt hepatic encephalopathy were screened using the number connection test and digit symbol test. The patients were randomized to receive probiotics (n = 30) or no probiotics (n = 37) for 3 months. At the end of the trial, changes in cognition, intestinal microbiota, venous ammonia, and intestinal mucosal barriers were analyzed using recommended systems biology techniques. Results The patients’ cognition was significantly improved after probiotic treatment. The predominant bacteria ( Clostridium cluster I and Bifidobacterium) were significantly enriched in the probiotics-treated group, while Enterococcus and Enterobacteriaceae were significantly decreased. Probiotic treatment was also associated with an obvious reduction in venous ammonia. Additionally, the parameters of the intestinal mucosal barrier were obviously improved after probiotic treatment, which might have contributed to the improved cognition and the decreased ammonia levels. Conclusion Treatment with probiotics containing C. butyricum and B. infantis represents a new adjuvant therapy for the management of MHE in patients with HBV-induced cirrhosis.


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