Phenotypic and functional characterization of intrahepatic T lymphocytes during chronic hepatitis C

Hepatology ◽  
2003 ◽  
Vol 38 (4) ◽  
pp. 829-841 ◽  
Author(s):  
Vincent Leroy ◽  
Ines Vigan ◽  
Jean-Francois Mosnier ◽  
Tania Dufeu-Duchesne ◽  
Martine Pernollet ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
T Lymphocytes ◽  
Chronic Hepatitis C ◽  
Functional Characterization

Characterization of elevated alanine aminotransferase levels during pegylated-interferon α-2b plus ribavirin treatment for chronic hepatitis C

2011 ◽  
Vol 41 (2) ◽  
pp. 118-125 ◽  
Author(s):  
Yo-hei Aoki ◽  
Shogo Ohkoshi ◽  
Satoshi Yamagiwa ◽  
Masahiko Yano ◽  
Hiromichi Takahashi ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Alanine Aminotransferase ◽  
Pegylated Interferon ◽  
Interferon Α

Clinical and laboratory characteristics of patients with chronic hepatitis C and severe interferon system suppression

2021 ◽  
Vol 19 (2) ◽  
pp. 60-64
Author(s):  
Zh.B. Ponezheva ◽  
◽  
I.V. Mannanova ◽  
V.V. Makashova ◽  
A.A. Erovichenkov ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
T Lymphocytes ◽  
Liver Fibrosis ◽  
Chronic Hepatitis C ◽  
Serum Levels ◽  
Control Group ◽  
Biochemical Activity ◽  
Duration Of Infection ◽  
Grade 3

Objective. To identify specific clinical and laboratory characteristics of patients with chronic hepatitis C (CHC) and severe interferon (IFN) system suppression. Patients and methods. This study was conducted at the Clinical Department of Infectious Pathology, Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing. We enrolled and examined 76 patients with confirmed CHC aged 18 to 80 years who had been followed up for at least 3 years. We analyzed the level of IFN-producing T-lymphocytes, IFN status, serum levels of IFN-α, -γ and -λ depending on viral and biochemical activity, and genotype. In addition to that, we evaluated the association between the IFN system parameters and age, duration of infection, genotype, viral load, and stage of liver fibrosis. The control group comprised 30 healthy individuals who had no complaints and no clinical or laboratory changes at the time of examination. Results. We identified 3 grades of IFN system suppression: grade 1–moderate (in 21% of patients), grade 2–mild (inadequate) (in 47% of patients), and grade 3–severe (in 32% of patients). We analyzed clinical and laboratory characteristics of patients with grade 3 IFN system suppression and evaluated the IFN system depending on age, duration of infection, genotype, viral and biochemical activity. We found that severe IFN system suppression correlated with duration of infection, stage of liver fibrosis with a tendency to increased levels of T-lymphocytes expressing receptors for IFN-α and IFN-γ (CD118+, CD119+). Key words: chronic hepatitis C, genotype, interferon status

Mo1444 CHARACTERIZATION OF PATIENTS WITH CHRONIC HEPATITIS C (C-HCV) ATTENDED AT A HEPATOLOGY CLINIC OF A COMMUNITY HOSPITAL IN NORTH BROOKLYN IN NEW YORK CITY (NYC).

2020 ◽  
Vol 158 (6) ◽  
pp. S-879
Author(s):  
Roshan Patel ◽  
Ahmed Shady ◽  
Tarek H. Alansari ◽  
Albina Aylyarova ◽  
Vivian Istafanos ◽  
...  
Keyword(s):  
New York ◽  
New York City ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
York City ◽  
Community Hospital

The role of hepatitis C virus specific CD4+ T lymphocytes in acute and chronic hepatitis C

1996 ◽  
Vol 74 (10) ◽  
pp. 583-588 ◽  
Author(s):  
H. M. Diepolder ◽  
R. Zachoval ◽  
R. M. Hoffmann ◽  
M.-C. Jung ◽  
T. Gerlach ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
T Lymphocytes ◽  
Chronic Hepatitis C ◽  
Acute And Chronic Hepatitis

scholarly journals Intrahepatic and circulating HLA class II-restricted, hepatitis C virus-specific T cells: Functional characterization in patients with chronic hepatitis C

Hepatology ◽  
2002 ◽  
Vol 35 (5) ◽  
pp. 1225-1236 ◽  
Author(s):  
Amalia Penna ◽  
Gabriele Missale ◽  
Vincenzo Lamonaca ◽  
Massimo Pilli ◽  
Cristina Mori ◽  
...  
Keyword(s):  
T Cells ◽  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Functional Characterization ◽  
Class Ii ◽  
Hla Class Ii

scholarly journals Reduced CC Chemokine Receptor (CCR) 1 and CCR5 Surface Expression on Peripheral Blood T Lymphocytes from Patients with Chronic Hepatitis C Infection

2002 ◽  
Vol 185 (12) ◽  
pp. 1803-1807 ◽  
Author(s):  
Mathias Lichterfeld ◽  
Ludger Leifeld ◽  
Hans Dieter Nischalke ◽  
Jürgen K. Rockstroh ◽  
Lothar Heß ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
T Lymphocytes ◽  
Chronic Hepatitis C ◽  
Chemokine Receptor ◽  
Peripheral Blood ◽  
Surface Expression ◽  
Hepatitis C Infection ◽  
Cc Chemokine

Tissue Characterization of Chronic Hepatitis C under Ultrasonography using Neural Network

2004 ◽  
Vol 2004.6 (0) ◽  
pp. 181-182
Author(s):  
Takanori KONNO ◽  
Yasukazu NISHI ◽  
Kazuyoshi HOSHINO ◽  
Toshikatsu OTANI ◽  
Risa TOUNE ◽  
...  
Keyword(s):  
Neural Network ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Tissue Characterization
Sign in / Sign up

Export Citation Format

Share Document