Intestinal-type adenocarcinoma of the larynx: Report of a rare aggressive phenotype and discussion of histogenesis

Head & Neck ◽  
2013 ◽  
Vol 36 (5) ◽  
pp. E44-E47 ◽  
Author(s):  
Diana Bell ◽  
Floyd Christopher Holsinger ◽  
Nelson Ordonez ◽  
Adel K. El-Naggar
Keyword(s):  
Intestinal Type ◽  
Aggressive Phenotype ◽  
Intestinal Type Adenocarcinoma

scholarly journals Nasopharyngeal non-intestinal-type adenocarcinoma: a case report and updated review of the literature

2017 ◽  
Vol 24 (1) ◽  
pp. 55 ◽  
Author(s):  
C. Jain ◽  
L. Caulley ◽  
K.I. Macdonald ◽  
B. Purgina ◽  
C.K. Lai ◽  
...  
Keyword(s):  
Radiation Treatment ◽  
Rare Condition ◽  
Intestinal Type ◽  
World Health ◽  
Primary Radiation ◽  
High Grade ◽  
Rare Tumours ◽  
Intestinal Type Adenocarcinoma ◽  
Health Organization ◽  
Nasopharyngeal Masses

Background Non-intestinal-type adenocarcinoma is a malignancy traditionally found in the sinonasal cavity. To our knowledge, this case is the first reported of this rare condition originating in the nasopharynx.Case Presentation A 67-year-old woman with nasopharyngeal non-intestinal-type adenocarcinoma, with an accompanying parapharyngeal mass received primary radiation treatment for both lesions. Her tumour subsequently persisted, with a concomitant conversion in pathology from a low- to a high-grade malignancy.Results Non-intestinal-type and intestinal-type adenocarcinomas of the nasopharynx are extremely rare tumours and do not appear in the World Health Organization classification system. We review the pathophysiologic features of these malignancies and propose modifications to the current classification system.Conclusions Non-intestinal-type adenocarcinoma should be included in the differential diagnosis of nasopharyngeal masses. In our experience, this tumour in this location showed a partial response to primary radiation but later converted from a low- to a high-grade adenocarcinoma.

scholarly journals RHOA mutations and CLDN18-ARHGAP fusions in intestinal-type adenocarcinoma with anastomosing glands of the stomach

2018 ◽  
Vol 32 (4) ◽  
pp. 568-575 ◽  
Author(s):  
Taiki Hashimoto ◽  
Reiko Ogawa ◽  
Tzu-Yin Tang ◽  
Hiroshi Yoshida ◽  
Hirokazu Taniguchi ◽  
...  
Keyword(s):  
Intestinal Type ◽  
Intestinal Type Adenocarcinoma

scholarly journals Sinonasal Non–Intestinal-Type Adenocarcinoma: A Retrospective Review of 22 Patients

2018 ◽  
Vol 120 ◽  
pp. e962-e969 ◽  
Author(s):  
Maurizio Bignami ◽  
Davide Lepera ◽  
Luca Volpi ◽  
Alessia Lambertoni ◽  
Alberto Arosio ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Intestinal Type ◽  
Intestinal Type Adenocarcinoma

Intestinal-Type Adenocarcinoma of the Sinonasal Tract: A Clinicopathologic Study of 18 Cases

1993 ◽  
Vol 79 (3) ◽  
pp. 205-210 ◽  
Author(s):  
Carmelo Urso ◽  
Maria Benedetta Ninu ◽  
Alessandro Franchi ◽  
Milena Paglierani ◽  
Roberto Bondi
Keyword(s):  
Intestinal Type ◽  
Presenting Symptoms ◽  
Clinicopathologic Study ◽  
Clinicopathologic Findings ◽  
Poorly Differentiated ◽  
Intestinal Type Adenocarcinoma ◽  
Aggressive Tumors ◽  
Well Differentiated ◽  
Colonic Adenocarcinomas

Background Intestinal-type adenocarcinoma (ITAC) of the nose and paranasal sinuses is a relatively rare tumor. It commonly affects subjects exposed to wood or leather dust. Methods The authors present the clinicopathologic findings of 18 cases of sinonasal ITACs and review the proposed histologic classifications. Results All patients, except one, were males; mean age was 60 years (range, 41-79); in 9 cases an occupational exposure to wood or leather dust was found. Common presenting symptoms were epistaxis, nasal obstruction and rhinorrhea. Histologically, tumors were divided into four groups: well-differentiated (G1) ITACs = 3 cases; moderately differentiated (G2) ITACs = 8 cases; poorly differentiated (G3) ITACs = 2 cases; mucinous (M) ITACs = 5 cases. Immunocytochemically, 16/17 cases were positive for carcinoembryonal antigen, 1/17 for somatostatin, and 0/16 cases for gastrin. Conclusions Sinonasal ITACs are aggressive tumors, often diagnosed in a relatively advanced stage. Owing the close similarity of the microscopic aspects, a histologic classification of ITACs analogous to that of colonic adenocarcinomas is proposed.

Histologic Classification of Sinonasal Intestinal-Type Adenocarcinoma

1991 ◽  
Vol 15 (4) ◽  
pp. 368-375 ◽  
Author(s):  
Douglas W. Franquemont ◽  
Robert E. Fechner ◽  
Stacey E. Mills
Keyword(s):  
Intestinal Type ◽  
Histologic Classification ◽  
Intestinal Type Adenocarcinoma

The First Reported Case of Primary Intestinal-type Adenocarcinoma of the Middle Ear and Review of the Literature

2017 ◽  
Vol 38 (9) ◽  
pp. e364-e368 ◽  
Author(s):  
Marc-Elie Nader ◽  
Diana Bell ◽  
Lawrence Ginsberg ◽  
Franco DeMonte ◽  
G. Brandon Gunn ◽  
...  
Keyword(s):  
Middle Ear ◽  
Intestinal Type ◽  
Review Of The Literature ◽  
Intestinal Type Adenocarcinoma

HER2 status in sinonasal intestinal-type adenocarcinoma

2019 ◽  
Vol 215 (6) ◽  
pp. 152432 ◽  
Author(s):  
Valeria Maffeis ◽  
Rocco Cappellesso ◽  
Alessia Zanon ◽  
Diego Cazzador ◽  
Enzo Emanuelli ◽  
...  
Keyword(s):  
Intestinal Type ◽  
Her2 Status ◽  
Intestinal Type Adenocarcinoma
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