Synthesis of novel chiral Schiff bases and their application in asymmetric transfer hydrogenation of prochiral ketones

2008 ◽  
Vol 19 (7) ◽  
pp. 682-687 ◽  
Author(s):  
Zhongqiang Zhou ◽  
Yongjun Bian
Keyword(s):  
Schiff Bases ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Prochiral Ketones

scholarly journals Asymmetric transfer hydrogenation of prochiral ketones catalyzed by aminosulfonamide-ruthenium complexes in ionic liquid

2011 ◽  
Vol 9 (1) ◽  
pp. 175-179 ◽  
Author(s):  
Zhongqiang Zhou ◽  
Yong Sun ◽  
Aiqing Zhang
Keyword(s):  
Ionic Liquid ◽  
Catalytic System ◽  
Ruthenium Complexes ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Prochiral Ketones

AbstractChiral aminosulfonamides containing imidazolium group were used as ligands for the ruthenium(II)-catalyzed asymmetric transfer hydrogenation of prochiral ketones in ionic liquid, affording good to excellent conversions and enantiomeric excesses. The catalytic system could be easily recovered and reused several times.

Asymmetric transfer hydrogenation of prochiral ketones in aqueous media with chiral water-soluble and heterogenized bifunctional catalysts of the RhCp*-type ligand

Chirality ◽  
2010 ◽  
Vol 23 (2) ◽  
pp. 178-184 ◽  
Author(s):  
Angélica Barrón-Jaime ◽  
Oscar F. Narvaez-Garayzar ◽  
Jorge González ◽  
Valentín Ibarra-Galván ◽  
Gerardo Aguirre ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Water Soluble ◽  
Transfer Hydrogenation ◽  
Bifunctional Catalysts ◽  
Asymmetric Transfer Hydrogenation ◽  
Prochiral Ketones

scholarly journals Computational Design of SCS Nickel Pincer Complexes for the Asymmetric Transfer Hydrogenation of 1-Acetonaphthone

Catalysts ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 101 ◽  
Author(s):  
Bing Qiu ◽  
Wan Wang ◽  
Xinzheng Yang
Keyword(s):  
Density Functional ◽  
Enantiomeric Excess ◽  
Density Functional Theory Calculations ◽  
Computational Design ◽  
Transfer Hydrogenation ◽  
Pincer Complexes ◽  
Free Energy Barrier ◽  
Asymmetric Transfer Hydrogenation ◽  
Functional Theory ◽  
Prochiral Ketones

Inspired by the active site structures of lactate racemase and recently reported sulphur–carbon–sulphur (SCS) nickel pincer complexes, a series of scorpion-like SCS nickel pincer complexes with an imidazole tail and asymmetric claws was proposed and examined computationally as potential catalysts for the asymmetric transfer hydrogenation of 1-acetonaphthone. Density functional theory calculations reveal a proton-coupled hydride transfer mechanism for the dehydrogenation of (R)-(+)-1-phenyl-ethanol and the hydrogenation of 1-acetonaphthone to produce (R)-(+)-1-(2-naphthyl)ethanol and (S)-(−)-1-(2-naphthyl)ethanol. Among all proposed Ni complexes, 1Ph is the most active one with a rather low free energy barrier of 24 kcal/mol and high enantioselectivity of near 99% enantiomeric excess (ee) for the hydrogenation of prochiral ketones to chiral alcohols.

New Ruthenium Catalysts for Asymmetric Transfer Hydrogenation of Prochiral Ketones.

ChemInform ◽  
2007 ◽  
Vol 38 (33) ◽  
Author(s):  
Stephan Enthaler ◽  
Bernhard Hagemann ◽  
Santosh Bhor ◽  
Gopinathan Anilkumar ◽  
Man Kin Tse ◽  
...  
Keyword(s):  
Ruthenium Catalysts ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Prochiral Ketones
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