scholarly journals Brain structural connectivity, anhedonia, and phenotypes of major depressive disorder: A structural equation model approach

2021 ◽  
Author(s):  
Julia‐Katharina Pfarr ◽  
Katharina Brosch ◽  
Tina Meller ◽  
Kai Gustav Ringwald ◽  
Simon Schmitt ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Structural Equation Model ◽  
Structural Equation ◽  
Structural Connectivity ◽  
Equation Model ◽  
Major Depressive ◽  
Model Approach

scholarly journals Indirect frontocingulate structural connectivity predicts clinical response to accelerated rTMS in major depressive disorder

2020 ◽  
pp. 243-252
Author(s):  
Deborah C.W. Klooster ◽  
Iris N. Vos ◽  
Karen Caeyenberghs ◽  
Alexander Leemans ◽  
Szabolcs David ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Clinical Response ◽  
Structural Connectivity ◽  
Major Depressive

scholarly journals Microstructural deficits in the thalamus of major depressive disorder

2021 ◽  
Author(s):  
Pengfei Xu ◽  
Gangqiang Hou ◽  
Yuxuan Zhang ◽  
Yingli Zhang ◽  
Hui Ai ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Large Scale ◽  
Gray Matter Volume ◽  
Structural Connectivity ◽  
Brain Network ◽  
Microstructural Properties ◽  
Major Depressive ◽  
T1 Relaxation ◽  
Structural Abnormalities

Macroscopic structural abnormalities in the thalamus and thalamic circuits have been shown to contribute to the neuropathology of major depressive disorder (MDD). However, cytoarchitectonic properties underlying these macroscopic abnormalities remain unknown. The purpose of this study was to identify systematic deficits of brain architecture in depression, from structural brain network organization to microstructural properties. A multi-modal neuroimaging approach including diffusion, anatomical and quantitative magnetic resonance imaging (MRI) was used to examine structural-related alternations in 56 MDD patients compared with 35 age- and sex-matched controls. Structural networks were constructed and analyzed using seed-based probabilistic tractography. Morphometric measurements, including cortical thickness and voxel-based morphometry (VBM), were evaluated across the whole brain. A conjunction analysis was then conducted to identify key regions showing common structural alternations across modalities. The microstructural properties, macromolecular tissue volume (MTV) and T1 relaxation times of identified key regions were then calculated. Results showed multiple alterations of structural connectivity within a set of subcortical areas and their connections to cortical regions in MDD patients. These subcortical regions included the putamen, thalamus and caudate, which are predominately involved in the limbic-cortical-striatal-pallidal-thalamic network (LCSPT). Structural connectivity was disrupted within and between large-scale networks, mainly including subcortical networks, default mode networks and salience/ventral attention networks. Consistently, these regions also exhibited widespread volume reductions in MDD patients, specifically the bilateral thalamus, left putamen and right caudate. Importantly, the microstructural properties, T1 relaxation time of left thalamus were increased and negatively correlated with its gray matter volume in MDD patients. The present work to date sheds light on the neuropathological disruptions of LCSPT circuit in MDD, providing the first multi-modal neuroimaging evidence for the macro-micro structural abnormalities of the thalamus in patients with MDD. These findings have implications in understanding the abnormal changes of brain structures across development of MDD.

scholarly journals The role of perceived stress and cognitive function on the relationship between neuroticism and depression among the elderly: a structural equation model approach

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mukda Banjongrewadee ◽  
Nahathai Wongpakaran ◽  
Tinakon Wongpakaran ◽  
Tanyong Pipanmekaporn ◽  
Yodying Punjasawadwong ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Structural Equation Model ◽  
Perceived Stress ◽  
Structural Equation ◽  
The Elderly ◽  
Equation Model ◽  
The Relationship ◽  
Model Approach

scholarly journals PENGARUH PEMBERDAYAAN ZAKAT DALAM MENINGKATKAN MODAL MANUSIA DAN KESEJAHTERAAN MASYARAKAT MISKIN

2020 ◽  
Vol 17 (1) ◽  
pp. 7-15
Author(s):  
Maimun Sholeh
Keyword(s):  
Human Capital ◽  
Structural Equation Model ◽  
Cross Section ◽  
Structural Equation ◽  
Equation Model ◽  
Probability Sampling ◽  
Purposive Sampling ◽  
The Poor ◽  
The Right ◽  
Model Approach

Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh Modal manusia dan pemberdayaan terhadap kesejahteraan masyarakat miskin khususnya masyarakat miskin yang diberdayakan oleh lembaga zakat  sehingga bisa dibuat strategi  yang tepat untuk meningkatkan kesehteraan mereka. Penelitian ini merupakan studi eksplanatori dilakukan dengan menggunakan pendekatan SEM (Structural Equation Model). Anggota sampel ditentukan dengan metode non-probability sampling khususnya dengan purposive sampling. Data dikumpulkan secara cross section dianalisis secara kuantitatif. Hasil penelitian menunjukkan bahwa baik modal manusia maupun pemberdayaan berpengaruh terhadap kesejahteraan masyarakat miskin khususnya masyarakat penerima pemberdayaan zakat. Abstract: This study aims to determine the effect of human capital and empowerment on the welfare of the poor, especially the poor, who are empowered by zakat institutions so that the right strategy can be made to improve their health. This research is a descriptive study conducted using the SEM (Structural Equation Model) approach. The sample members are determined by the non-probability sampling method, especially by purposive sampling. Data were collected by cross-section and analyzed quantitatively. The results showed that both human capital and empowerment affected the welfare of the poor, especially those who received zakat empowerment.

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