Ophthalmic changes in a spaceflight analog are associated with brain functional reorganization

The impairment in episodic memory system is the best-known cognitive deficit in patients with temporal lobe epilepsy (TLE). Recent studies have shown evidence of semantic disorders, but they have been less studied than episodic memory. The semantic dysfunction in TLE has various cognitive manifestations, such as the presence of language disorders characterized by defects in naming, verbal fluency, or remote semantic information retrieval, which affects the ability of patients to interact with their surroundings. This paper is a review of recent research about the consequences of TLE on semantic processing, considering neuropsychological, electrophysiological, and neuroimaging findings, as well as the functional role of the hippocampus in semantic processing. The evidence from these studies shows disturbance of semantic memory in patients with TLE and supports the theory of declarative memory of the hippocampus. Functional neuroimaging studies show an inefficient compensatory functional reorganization of semantic networks and electrophysiological studies show a lack of N400 effect that could indicate that the deficit in semantic processing in patients with TLE could be due to a failure in the mechanisms of automatic access to lexicon.

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Brain functional reorganization in children with hemiplegic cerebral palsy: Assessment with TMS and therapeutic perspectives

Neurophysiologie Clinique ◽

10.1016/j.neucli.2021.09.002 ◽

2021 ◽

Author(s):

Raffaele Nardone ◽

Luca Sebastianelli ◽

Davide Ferrazzoli ◽

Francesco Brigo ◽

Piergiorgio Lochner ◽

...

Keyword(s):

Cerebral Palsy ◽

Functional Reorganization ◽

Hemiplegic Cerebral Palsy

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Glucose Effects on the Peritoneum: What Can We Learn from Rodent Models?

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-0032-1304572 ◽

2012 ◽

Vol 120 (04) ◽

pp. 197-198 ◽

Cited By ~ 2

Author(s):

S. Müller-Krebs ◽

W. Zhang ◽

L. Kihm ◽

J. Reiser ◽

P. Nawroth ◽

...

Keyword(s):

Vitamin B1 ◽

Rodent Models ◽

Peritoneal Membrane ◽

Advanced Glycation ◽

Detoxifying Enzymes ◽

Functional Reorganization ◽

Glycation End Products ◽

Glucose Metabolites ◽

Glucose Effects

AbstractDuring long-term peritoneal dialysis (PD) the peritoneal membrane underlies processes of structural and functional reorganization mediated by high glucose and reactive glucose metabolites that are contained in PD solutions; this process is accompanied by increasing fibrosis. Mechanistically, the peritoneal damage is triggered by the interaction of advanced glycation end-products with their receptor; this is true for rodents as well as for humans. With this knowledge interventional strategies can be tested in rodent models, among them are the lipid soluble vitamin B1 analogue benfotiamine (BF) or detoxifying enzymes such as glyoxalase. Of additional interest is the finding that PD fluids do not only cause local but also systemic damage, in particular renal and cardiovascular. In the case of kidney damage, the intervention with BF was also successful. Taken together, PD can be regarded as a local model for long-term diabetes together with systemic aspects of damage.

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Combined PET and electrophysiological study on the pathophysiology of motor deficit and functional reorganization in patients with brain tumor and infarction

NeuroImage ◽

10.1016/s1053-8119(96)80503-9 ◽

1996 ◽

Vol 3 (3) ◽

pp. S501

Author(s):

T. Nariai ◽

M. Senda ◽

K. Ishii ◽

H. Toyama ◽

S. Wakabayashi ◽

...

Keyword(s):

Brain Tumor ◽

Electrophysiological Study ◽

Motor Deficit ◽

Functional Reorganization

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Functional reorganization of the human auditory pathways following hemispherectomy: An fMRI demonstration

Neuropsychologia ◽

10.1016/j.neuropsychologia.2008.06.009 ◽

2008 ◽

Vol 46 (12) ◽

pp. 2936-2942 ◽

Cited By ~ 11

Author(s):

P. Paiement ◽

F. Champoux ◽

B.A. Bacon ◽

M. Lassonde ◽

J.-P. Gagné ◽

...

Keyword(s):

Auditory Pathways ◽

Functional Reorganization

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Rapid Axonal Sprouting and Pruning Accompany Functional Reorganization in Primary Visual Cortex

Neuron ◽

10.1016/j.neuron.2009.11.026 ◽

2009 ◽

Vol 64 (5) ◽

pp. 719-729 ◽

Cited By ~ 121

Author(s):

Homare Yamahachi ◽

Sally A. Marik ◽

Justin N.J. McManus ◽

Winfried Denk ◽

Charles D. Gilbert

Keyword(s):

Visual Cortex ◽

Primary Visual Cortex ◽

Axonal Sprouting ◽

Functional Reorganization

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