scholarly journals Tracking cerebral blood flow in BOLD fMRI using recursively generated regressors

2014 ◽  
Vol 35 (11) ◽  
pp. 5471-5485 ◽  
Author(s):  
Yunjie Tong ◽  
Blaise deB. Frederick
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Bold Fmri ◽  
Generated Regressors

scholarly journals Relations between BOLD fMRI-Derived Resting Brain Activity and Cerebral Blood Flow

PLoS ONE ◽  
2012 ◽  
Vol 7 (9) ◽  
pp. e44556 ◽  
Author(s):  
Zhengjun Li ◽  
Yisheng Zhu ◽  
Anna Rose Childress ◽  
John A. Detre ◽  
Ze Wang
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Brain Activity ◽  
Bold Fmri

scholarly journals Interictal cortical hyperresponsiveness in migraine is directly related to the presence of aura

Cephalalgia ◽  
2013 ◽  
Vol 33 (6) ◽  
pp. 365-374 ◽  
Author(s):  
Ritobrato Datta ◽  
Geoffrey K Aguirre ◽  
Siyuan Hu ◽  
John A Detre ◽  
Brett Cucchiara
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Visual Stimulus ◽  
Visual Stimulation ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen Level ◽  
Visual Discomfort ◽  
Bold Fmri ◽  
Control Subjects ◽  
And Control

Objective The objective of this study was to compare the interictal cortical response to a visual stimulus between migraine with aura (MWA), migraine without aura (MwoA), and control subjects. Methods In a prospective case-control study, blood oxygen level-dependent functional magnetic resonance imaging (BOLD fMRI) was used to assess the response to a visual stimulus and arterial spin labeled perfusion MR to determine resting cerebral blood flow. A standardized questionnaire was used to assess interictal visual discomfort. Results Seventy-five subjects (25 MWA, 25 MwoA, and 25 controls) were studied. BOLD fMRI response to visual stimulation within primary visual cortex was greater in MWA (3.09 ± 0.15%) compared to MwoA (2.36 ± 0.13%, p = 0.0008) and control subjects (2.47 ± 0.11%, p = 0.002); responses were also greater in the lateral geniculate nuclei in MWA. No difference was found between MwoA and control groups. Whole brain analysis showed that increased activation in MWA was confined to the occipital pole. Regional resting cerebral blood flow did not differ between groups. MWA and MwoA subjects had significantly greater levels of interictal visual discomfort compared to controls ( p = 0.008 and p = 0.005, respectively), but this did not correlate with BOLD response. Conclusions Despite similar interictal symptoms of visual discomfort, only MWA subjects have cortical hyperresponsiveness to visual stimulus, suggesting a direct connection between cortical hyperresponsiveness and aura itself.

scholarly journals Relative changes of cerebral arterial and venous blood volumes during increased cerebral blood flow: Implications for BOLD fMRI

2001 ◽  
Vol 45 (5) ◽  
pp. 791-800 ◽  
Author(s):  
Sang-Pil Lee ◽  
Timothy Q. Duong ◽  
Guang Yang ◽  
Costantino Iadecola ◽  
Seong-Gi Kim
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Venous Blood ◽  
Bold Fmri ◽  
Blood Volumes

scholarly journals Caffeine-induced uncoupling of cerebral blood flow and oxygen metabolism: A calibrated BOLD fMRI study

NeuroImage ◽  
2008 ◽  
Vol 40 (1) ◽  
pp. 237-247 ◽  
Author(s):  
Joanna E. Perthen ◽  
Amy E. Lansing ◽  
Joy Liau ◽  
Thomas T. Liu ◽  
Richard B. Buxton
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Oxygen Metabolism ◽  
Bold Fmri ◽  
Fmri Study

scholarly journals Poststimulus undershoots in cerebral blood flow and BOLD fMRI responses are modulated by poststimulus neuronal activity

2013 ◽  
Vol 110 (33) ◽  
pp. 13636-13641 ◽  
Author(s):  
K. J. Mullinger ◽  
S. D. Mayhew ◽  
A. P. Bagshaw ◽  
R. Bowtell ◽  
S. T. Francis
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Neuronal Activity ◽  
Bold Fmri

scholarly journals Regional differences in the coupling of cerebral blood flow and oxygen metabolism changes in response to activation: Implications for BOLD-fMRI

NeuroImage ◽  
2008 ◽  
Vol 39 (4) ◽  
pp. 1510-1521 ◽  
Author(s):  
Beau M. Ances ◽  
Oleg Leontiev ◽  
Joanna E. Perthen ◽  
Christine Liang ◽  
Amy E. Lansing ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Differences ◽  
Oxygen Metabolism ◽  
Bold Fmri
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