scholarly journals Cerebral blood flow and BOLD fMRI responses to hypoxia in awake and anesthetized rats

2007 ◽  
Vol 1135 ◽  
pp. 186-194 ◽  
Author(s):  
Timothy Q. Duong
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Bold Fmri ◽  
Anesthetized Rats

scholarly journals Effect of nicotine on cerebral blood flow in anesthetized rats.

1996 ◽  
Vol 71 ◽  
pp. 175
Author(s):  
Hiroshi Uramoto ◽  
Yoshihiro Tani ◽  
Kyoshi Saito ◽  
Tomochika Ohno
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Anesthetized Rats

scholarly journals Blood—Brain Barrier Transport of Butanol and Water Relative to N-Isopropyl-p-Iodoamphetamine as the Internal Reference

1985 ◽  
Vol 5 (2) ◽  
pp. 275-281 ◽  
Author(s):  
William M. Pardridge ◽  
Gary Fierer
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Internal Reference ◽  
Diffusion Restriction ◽  
Blood Brain ◽  
Anesthetized Rats ◽  
Rat Forebrain ◽  
The Brain

The literature regarding the blood–brain barrier (BBB) transport of butanol is conflicting as studies report both incomplete and complete extraction of butanol by the brain. In this work the BBB transport of both [14C]butanol and [3H]water was studied using the carotid injection technique in conscious and in ketamine- or pentobarbital-anesthetized rats employing N-isopropyl- p-[125I]iodoamphetamine ([125I]IMP) as the internal reference and as a fluid microsphere. The three isotopes (3H, 125I, 14C) were conveniently counted simultaneously in a liquid scintillation spectrometer. IMP is essentially completely sequestered by the brain for at least 1 min in conscious rats and for 2 min in anesthetized animals. Butanol extraction by rat forebrain is not flow limited but ranges between 77 ± 1 and 87 ± 1% for the three conditions. The incomplete extraction of butanol by the forebrain is due to diffusion restriction of butanol clearance in some regions (frontal cortex, colliculi) but not in others (caudate, hippocampus, olfactory bulb). The permeability-surface area product/cerebral blood flow ratio of butanol and water in rat forebrain remains relatively constant, 1.7 ± 0.2 and 1.0 ± 0.1, respectively, despite a twofold increase in cerebral blood flow in conscious relative to pentobarbital-anesthetized rats. The absence of an inverse relationship between flow and butanol or water extraction is consistent with capillary recruitment being the principal mechanism underlying changes in cerebral blood flow in anesthesia. The diffusion restriction of BBB transport of butanol in some regions, but not in others, necessitates a careful regional analysis of BBB permeability to butanol prior to usage of this compound as a cerebral blood flow marker.

Cerebral blood flow decreases following microinjection of sodium nitroprusside into the nucleus tractus solitarii of anesthetized rats

1996 ◽  
Vol 432 (5) ◽  
pp. 941-943 ◽  
Author(s):  
Masaiwa Inoue ◽  
Masanobu Maeda ◽  
Seiji Takao ◽  
Masatsugu Nakai ◽  
Takeo Fukushima ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Sodium Nitroprusside ◽  
Nucleus Tractus Solitarii ◽  
Anesthetized Rats

Effects of microinjection of acid into the nucleus tractus solitarii on cerebral blood flow in anesthetized rats

1994 ◽  
Vol 49 (2) ◽  
pp. 159-170 ◽  
Author(s):  
Michiharu Morino ◽  
Masanobu Maeda ◽  
Masatsugu Nakai ◽  
Abbott J. Krieger ◽  
Hreday N. Sapru
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Nucleus Tractus Solitarii ◽  
Anesthetized Rats

Effect of acupuncture-like stimulation on cortical cerebral blood flow in anesthetized rats

2002 ◽  
Vol 1238 ◽  
pp. 89-96 ◽  
Author(s):  
Sae Uchida ◽  
Atsuko Suzuki ◽  
Fusako Kagitani ◽  
Yoshihiro Aikawa
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Anesthetized Rats ◽  
Cortical Cerebral Blood Flow

scholarly journals Effect of Acupuncture-Like Stimulation on Cortical Cerebral Blood Flow in Anesthetized Rats.

2000 ◽  
Vol 50 (5) ◽  
pp. 495-507 ◽  
Author(s):  
Sae Uchida ◽  
Fusako Kagitani ◽  
Atsuko Suzuki ◽  
Yoshihiro Aikawa
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Anesthetized Rats ◽  
Cortical Cerebral Blood Flow
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