scholarly journals Functional integrity of thalamocortical circuits differentiates normal aging from mild cognitive impairment

2009 ◽  
Vol 30 (12) ◽  
pp. 3944-3957 ◽  
Author(s):  
Jose L. Cantero ◽  
Mercedes Atienza ◽  
German Gomez-Herrero ◽  
Abel Cruz-Vadell ◽  
Eulogio Gil-Neciga ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Normal Aging ◽  
Functional Integrity

scholarly journals Entorhinal cortex volume is associated with episodic memory related brain activation in normal aging and amnesic mild cognitive impairment

2011 ◽  
Vol 5 (2) ◽  
pp. 126-136 ◽  
Author(s):  
Mehul A. Trivedi ◽  
Travis R. Stoub ◽  
Christopher M. Murphy ◽  
Sarah George ◽  
Leyla deToledo-Morrell ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Episodic Memory ◽  
Entorhinal Cortex ◽  
Brain Activation ◽  
Normal Aging ◽  
Amnesic Mild Cognitive Impairment

IC-P-058: Metabolism and BOLD measures of the resting state network: A comparative study in normal aging and Mild Cognitive Impairment

2009 ◽  
Vol 5 (4S_Part_1) ◽  
pp. P27-P28
Author(s):  
Katell Mevel ◽  
Brigitte Landeau ◽  
Florence Mézenge ◽  
Nicolas Villain ◽  
Marine Fouquet ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Comparative Study ◽  
Resting State ◽  
Normal Aging ◽  
Resting State Network

scholarly journals Working Memory and Executive Function Decline across Normal Aging, Mild Cognitive Impairment, and Alzheimer’s Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Anna-Mariya Kirova ◽  
Rebecca B. Bays ◽  
Sarita Lagalwar
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Working Memory ◽  
Cognitive Impairment ◽  
Executive Function ◽  
Mild Cognitive Impairment ◽  
Executive Dysfunction ◽  
Normal Aging ◽  
Future Research ◽  
Neurological Differences

Alzheimer’s disease (AD) is a progressive neurodegenerative disease marked by deficits in episodic memory, working memory (WM), and executive function. Examples of executive dysfunction in AD include poor selective and divided attention, failed inhibition of interfering stimuli, and poor manipulation skills. Although episodic deficits during disease progression have been widely studied and are the benchmark of a probable AD diagnosis, more recent research has investigated WM and executive function decline during mild cognitive impairment (MCI), also referred to as the preclinical stage of AD. MCI is a critical period during which cognitive restructuring and neuroplasticity such as compensation still occur; therefore, cognitive therapies could have a beneficial effect on decreasing the likelihood of AD progression during MCI. Monitoring performance on working memory and executive function tasks to track cognitive function may signal progression from normal cognition to MCI to AD. The present review tracks WM decline through normal aging, MCI, and AD to highlight the behavioral and neurological differences that distinguish these three stages in an effort to guide future research on MCI diagnosis, cognitive therapy, and AD prevention.

P300 responses are associated with subcortical gray matter volume in amnestic mild cognitive impairment and normal aging

2016 ◽  
Vol 108 ◽  
pp. 100
Author(s):  
Derya Durusu Emek-Sava ◽  
Berrin Çavuşoğlu ◽  
Duygu Hünerli ◽  
Deniz Yerlikaya ◽  
Arife Gökçeoğlu ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Normal Aging ◽  
Amnestic Mild Cognitive Impairment ◽  
Matter Volume
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