scholarly journals Calibration of BOLD fMRI using breath holding reduces group variance during a cognitive task

2006 ◽  
Vol 28 (1) ◽  
pp. 59-68 ◽  
Author(s):  
Moriah E. Thomason ◽  
Lara C. Foland ◽  
Gary H. Glover
2015 ◽  
Vol 26 (2) ◽  
pp. 232-239 ◽  
Author(s):  
Amir Iranmahboob ◽  
Kyung K. Peck ◽  
Nicole P. Brennan ◽  
Sasan Karimi ◽  
Ryan Fisicaro ◽  
...  

Author(s):  
Chun‐Ming Chen ◽  
Hui‐Chieh Yang ◽  
Hsin‐Hua Hsieh ◽  
Tsai‐Ying Liao ◽  
Yen‐Chih Huang ◽  
...  

2021 ◽  
Vol 226 (4) ◽  
pp. 1229-1239
Author(s):  
Kai Chen ◽  
Hang Yang ◽  
Heming Zhang ◽  
Chun Meng ◽  
Benjamin Becker ◽  
...  

2021 ◽  
Vol 1 (2) ◽  
pp. 100021
Author(s):  
Jörg Larsen ◽  
Kai Kallenberg ◽  
Johanna Rühlmann ◽  
Jürgen Baudewig ◽  
Eike A. Nickel ◽  
...  

2017 ◽  
Author(s):  
Henning U. Voss ◽  
Kyung K. Peck ◽  
Nicole M. Petrovich Brennan ◽  
Andrei I. Holodny

AbstractPurposePreoperative functional MRI (fMRI) is limited by a muted BOLD response caused by abnormal vasoreactivity and resultant neurovascular uncoupling adjacent to malignant brain tumors. We propose to overcome this limitation and more accurately identify eloquent areas adjacent to brain tumors by independently assessing vasoreactivity using breath-holding and incorporating these data into the BOLD analysis.MethodsLocal vasoreactivity using a breath-holding paradigm with the same timing as the functional motor and language tasks was determined in 16 patients (9 glioblastomas, 1 anaplastic astrocytoma, 5 low grade astrocytomas, and 1 metastasis). We derived a model based on coherence for analyzing BOLD fMRI that takes into account the altered hemodynamics adjacent to brain tumors.ResultsActivation maps computed using the coherence model were overall similar to standard activation maps. However, the coherence maps demonstrated clinically meaningful areas of activation that were not seen using the standard method in 12/16 cases. This included localization of language areas adjacent to brain tumors, where the coherence method results were confirmed by intra-operative direct cortical stimulation. Enhanced task response maps based on vasoreactivity mapping demonstrated more robust, anatomically-correct activation, in particular adjacent to tumors as compared to maps obtained without vasoreactivity information.ConclusionsThe present preliminary results demonstrate the principle that the neurovascular uncoupling known to affect the accuracy of BOLD fMRI adjacent to brain tumors may be, at least partially, overcome by incorporating an independent measurement of vasoreactivity into the BOLD analysis.


2007 ◽  
Vol 41 (7) ◽  
pp. 33
Author(s):  
PATRICE WENDLING
Keyword(s):  

2001 ◽  
Vol 6 (1) ◽  
pp. 15-25 ◽  
Author(s):  
Harald Walach ◽  
Stefan Schmidt ◽  
Yvonne-Michelle Bihr ◽  
Susanne Wiesch

We studied the effect of experimenter expectations and different instructions in a balanced placebo design. 157 subjects were randomized into a 2 × 4 factorial design. Two experimenters were led to expect placebos either to produce physiological effects or not (pro- vs. antiplacebo). All subjects except a control group received a caffeine placebo. They were either made to expect coffee, no coffee, or were in a double-blind condition. Dependent measures were blood pressure, heart rate, well-being, and a cognitive task. There was one main effect on the instruction factor (p = 0.03) with the group “told no caffeine” reporting significantly better well-being. There was one main effect on the experimenter factor with subjects instructed by experimenter “proplacebo” having higher systolic blood pressure (p = 0.008). There was one interaction with subjects instructed by experimenter “proplacebo” to receive coffee doing worse in the cognitive task than the rest. Subjects instructed by experimenter “antiplacebo” were significantly less likely to believe the experimental instruction, and that mostly if they had been instructed to receive coffee. Contrary to the literature we could not show an effect of instruction, but there was an effect of experimenters. It is likely, however, that these experimenter effects were not due to experimental manipulations, but to the difference in personalities.


2019 ◽  
Vol 35 (6) ◽  
pp. 878-890 ◽  
Author(s):  
David Marcusson-Clavertz ◽  
Oscar N. E. Kjell

Abstract. Thinking about task-unrelated matters (mind wandering) is related to cognition and well-being. However, the relations between mind wandering and other psychological variables may depend on whether the former commence spontaneously or deliberately. The current two studies investigated the psychometric properties of the Spontaneous and Deliberate Mind Wandering Scales (SDMWS; Carriere, Seli, & Smilek, 2013 ). Study 1 evaluated the stability of the scales over 2 weeks ( N = 284 at Time 1), whereas Study 2 ( N = 323) evaluated their relations to Generalized anxiety disorder symptoms, Openness, Social desirability, and experience-sampling reports of intentional and unintentional mind wandering during an online cognitive task. The results indicated that the SDMWS were better fitted with a two-factor than a one-factor solution, although the fit was improved with the exclusion of one item. The scales exhibited strong measurement invariance across gender and time, and moderately high test-retest reliability. Spontaneous mind wandering predicted Generalized anxiety disorder and experience-sampling reports of unintentional mind wandering, whereas Deliberate mind wandering predicted Openness and experience-sampling reports of intentional mind wandering. Furthermore, Spontaneous mind wandering showed a negative association with social desirability of weak-to-medium strength. In sum, the scales generally showed favorable psychometric properties.


Author(s):  
Leonard Reinecke ◽  
Sabine Trepte

Abstract. This quasi-experimental study examined the effects of exposure to a computer game on arousal and subsequent task performance. After inducing a state of low arousal, participants were assigned to experimental or control conditions via self-selection. Members of the experimental group played a computer game for five minutes; subjects in the control group spent the same amount of time awaiting further instructions. Participants who were exposed to the computer game showed significantly higher levels of arousal and performed significantly better on a subsequent cognitive task. The pattern of results was not influenced by the participants' prior experience with the game. The findings indicate that mood-management processes associated with personal media use at the workplace go beyond the alteration of arousal and affect subsequent cognitive performance.


Author(s):  
Laura G. Militello ◽  
Robert J. B. Hutton ◽  
Rebecca M. Pliske ◽  
Betsy J. Knight ◽  
Gary Klein ◽  
...  

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