scholarly journals Different patterns of gray matter atrophy in behavioral variant frontotemporal dementia with and without episodic memory impairment

2021 ◽  
Author(s):  
Elisa de Paula França Resende ◽  
Michael Hornberger ◽  
Henrique Cerqueira Guimarães ◽  
Leandro Boson Gambogi ◽  
Luciano Inácio Mariano ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Frontotemporal Dementia ◽  
Gray Matter ◽  
Memory Impairment ◽  
Behavioral Variant Frontotemporal Dementia ◽  
Gray Matter Atrophy

P3-199: Episodic memory impairment in behavioral-variant frontotemporal dementia: A neuropsychological and a neuroimaging study

2015 ◽  
Vol 11 (7S_Part_15) ◽  
pp. P709-P709
Author(s):  
Leonardo Cruz de Souza ◽  
Henrique Cerqueira Guimarães ◽  
Maxime Bertoux ◽  
Michael Hornberger ◽  
Leandro Boson Gambogi ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Frontotemporal Dementia ◽  
Memory Impairment ◽  
Behavioral Variant Frontotemporal Dementia ◽  
Neuroimaging Study

IC-P-018: 3D mapping of gray matter atrophy in semantic dementia and frontal variant frontotemporal dementia

2006 ◽  
Vol 2 ◽  
pp. S661-S662
Author(s):  
Liana G. Apostolova ◽  
David G. Clark ◽  
Charleen Zoumalan ◽  
Calen A. Steiner ◽  
Aaron McMurtray ◽  
...  
Keyword(s):  
Frontotemporal Dementia ◽  
Gray Matter ◽  
Semantic Dementia ◽  
3D Mapping ◽  
Gray Matter Atrophy

Neural Correlates of Activities of Daily Living in Frontotemporal Dementia

2013 ◽  
Vol 26 (1) ◽  
pp. 51-57 ◽  
Author(s):  
E. Mioshi ◽  
J. R. Hodges ◽  
M. Hornberger
Keyword(s):  
Activities Of Daily Living ◽  
Frontotemporal Dementia ◽  
Gray Matter ◽  
Daily Living ◽  
Functional Disability ◽  
Neural Correlates ◽  
Voxel Based Morphometry ◽  
Tailored Interventions ◽  
Gray Matter Atrophy ◽  
Patient Groups

Background: Little research to date has investigated neural correlates of functional disability in frontotemporal dementia (FTD). Methods: Activities of daily living (ADL) were covaried against gray matter atrophy regions via Voxel-based morphometry in FTD (n = 52) and contrasted against a dementia control Alzheimer disease (AD) group (n = 20) and healthy age-matched controls (n = 18). Results: Both patient groups had similar ADL scores. However, FTD and AD differed on the gray matter atrophy areas associated with ADL scores. The FTD showed involvement of prefrontal and thalamus regions while AD showed widespread temporal, parietal, frontal, and caudate atrophy correlating with ADL dysfunction. Importantly, only the left superior frontal gyrus was implicated in ADL dysfunction for both FTD and AD. Conclusions: Differences in underlying neural correlates of ADL impairment have important clinical implications as these differences should be taken into account when interventions are planned. Dementia subtypes might require specifically tailored interventions for functional disability.

Episodic Memory Dysfunction in Behavioral Variant Frontotemporal Dementia: A Clinical And FDG-PET Study

2017 ◽  
Vol 57 (4) ◽  
pp. 1251-1264 ◽  
Author(s):  
Marta Fernández-Matarrubia ◽  
Jordi A. Matías-Guiu ◽  
María Nieves Cabrera-Martín ◽  
Teresa Moreno-Ramos ◽  
María Valles-Salgado ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Frontotemporal Dementia ◽  
Fdg Pet ◽  
Memory Dysfunction ◽  
Behavioral Variant Frontotemporal Dementia

scholarly journals Meta-analytic Review of Memory Impairment in Behavioral Variant Frontotemporal Dementia

2018 ◽  
Vol 24 (6) ◽  
pp. 593-605 ◽  
Author(s):  
Jackie M. Poos ◽  
Lize C. Jiskoot ◽  
Janne M. Papma ◽  
John C. van Swieten ◽  
Esther van den Berg
Keyword(s):  
Episodic Memory ◽  
Frontotemporal Dementia ◽  
Memory Performance ◽  
Meta Analysis ◽  
Verbal Working Memory ◽  
Exclusion Criterion ◽  
Case Control Studies ◽  
Behavioral Variant Frontotemporal Dementia ◽  
Analytic Review ◽  
Better Than

AbstractObjectives: A meta-analysis of the extent, nature and pattern of memory performance in behavioral variant frontotemporal dementia (bvFTD). Multiple observational studies have challenged the relative sparing of memory in bvFTD as stated in the current diagnostic criteria. Methods: We performed a meta-analytic review covering the period 1967 to February 2017 of case-control studies on episodic memory in bvFTD versus control participants (16 studies, 383 patients, 603 control participants), and patients with bvFTD versus those with Alzheimer’s disease (AD) (20 studies, 452 bvFTD, 874 AD). Differences between both verbal and non-verbal working memory, episodic memory learning and recall, and recognition memory were examined. Data were extracted from the papers and combined into a common metric measure of effect, Hedges’ d. Results: Patients with bvFTD show large deficits in memory performance compared to controls (Hedges’ d –1.10; 95% confidence interval [CI] [–1.23, –0.95]), but perform significantly better than patients with AD (Hedges’ d 0.85; 95% CI [0.69, 1.03]). Learning and recall tests differentiate best between patients with bvFTD and AD (p<.01). There is 37–62% overlap in test scores between the two groups. Conclusions: This study points to memory disorders in patients with bvFTD, with performance at an intermediate level between controls and patients with AD. This indicates that, instead of being an exclusion criterion for bvFTD diagnosis, memory deficits should be regarded as a potential integral part of the clinical spectrum. (JINS, 2018, 24, 593–605)

scholarly journals P1-223: MORE ATROPHY OF DEEP GRAY MATTER STRUCTURES IN BEHAVIORAL VARIANT FRONTOTEMPORAL DEMENTIA COMPARED TO ALZHEIMER'S DISEASE

2014 ◽  
Vol 10 ◽  
pp. P385-P386
Author(s):  
Christiane Möller ◽  
Nikki Dieleman ◽  
Wiesje M. Van der Flier ◽  
Adriaan Versteeg ◽  
Yolande Pijnenburg ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Frontotemporal Dementia ◽  
Gray Matter ◽  
Behavioral Variant Frontotemporal Dementia ◽  
Deep Gray Matter

Gray matter atrophy pattern in elderly with subjective memory impairment

2014 ◽  
Vol 10 (1) ◽  
pp. 99-108 ◽  
Author(s):  
Jessica Peter ◽  
Lukas Scheef ◽  
Ahmed Abdulkadir ◽  
Henning Boecker ◽  
Michael Heneka ◽  
...  
Keyword(s):  
Gray Matter ◽  
Memory Impairment ◽  
Subjective Memory ◽  
Subjective Memory Impairment ◽  
Gray Matter Atrophy
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