Neuropsychiatric symptoms and Quality of Life in patients with very mild and mild Alzheimer's disease

2010 ◽  
Vol 26 (5) ◽  
pp. 473-482 ◽  
Author(s):  
Kristiina Karttunen ◽  
Pertti Karppi ◽  
Asta Hiltunen ◽  
Matti Vanhanen ◽  
Tarja Välimäki ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neuropsychiatric Symptoms

scholarly journals Effects of cognitive stimulation on neuropsychiatric symptoms in elderly with Alzheimer's disease: A systematic review

2016 ◽  
Vol 10 (3) ◽  
pp. 178-184 ◽  
Author(s):  
Raiana Lídice Mór Fukushima ◽  
Elisangela Gisele do Carmo ◽  
Renata do Valle Pedroso ◽  
Pollyanna Natalia Micali ◽  
Paula Secomandi Donadelli ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Elderly Patients ◽  
Neuropsychiatric Symptoms ◽  
Cognitive Stimulation ◽  
Controlled Trials ◽  
Inclusion Criteria

ABSTRACT Introduction: Neuropsychiatric symptoms are frequent in Alzheimer's disease and negatively affect patient quality of life. Objective: To assess the effectiveness of cognitive stimulation on neuropsychiatric symptoms in elderly patients with Alzheimer's disease. Methods: The included articles were reviewed between December 2015 and June 2016, and the inclusion criteria were: (1) studies involving older adults diagnosed with Alzheimer's disease; (2) studies published in English, Spanish or Portuguese; (3) studies that determined the effect of cognitive stimulation on neuropsychiatric symptoms in elderly patients with Alzheimer's disease; (4) controlled trials. Results: Out of the total 722, 9 articles matched the inclusion criteria. Depression, apathy and anxiety were the most frequent symptoms. Conclusion: Studies reported significant results post-treatment, suggesting cognitive stimulation can be effective for these neuropsychiatric symptoms, thus improving the quality of life of Alzheimer's disease patients and their caregivers.

Determinants of quality of life in Alzheimer's disease: perspective of patients, informal caregivers, and professional caregivers

2012 ◽  
Vol 24 (11) ◽  
pp. 1805-1815 ◽  
Author(s):  
Maria Gómez-Gallego ◽  
Jesus Gómez-Amor ◽  
Juan Gómez-García
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Medical Condition ◽  
Neuropsychiatric Symptoms ◽  
Chronic Medical Condition ◽  
Psychotic Symptoms ◽  
Sources Of Information ◽  
Healthcare Staff

AbstractBackground: Alzheimer's disease (AD) is a chronic medical condition with symptoms that compromise patients’ quality of life (QoL). The identification of the factor predicting QoL in AD is essential to develop more effective interventions. Recent research suggests that these factors could be different for the distinct informants. This study explores the QoL predictors considering three different sources of information: patients, caregivers, and healthcare staff.Methods: In this cross-sectional study, a sample of 102 patients, their primary caregivers, and 15 members of the healthcare staff evaluated patients’ QoL (QoL-AD Scale). Patients’ and caregivers’ demographic and clinical data (cognitive function, neuropsychiatric symptoms, depression, and caregivers’ burden) were considered as QoL predictors.Results: In multivariate-adjusted linear regression analyses, we observed that patients’ ratings were mainly affected by their mood whereas caregivers’ ratings were also negatively influenced by patients’ irritability and burden. According to staff ratings, both psychotic symptoms and neuroleptics were associated with lower QoL.Conclusions: Our findings suggest that depression is the main variable related to patients’ QoL and that more careful management of neuropsychiatric disorders is necessary. Both proxies’ ratings are not equivalent to patients’ reports in terms of predictors but they are complementary. Thus, a thorough QoL assessment should consider separately the perspective of the different informants.

Quality of Life in relation to neuropsychiatric symptoms in Alzheimer's disease: 5-year prospective ALSOVA cohort study

2017 ◽  
Vol 33 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Kristiina Hongisto ◽  
Ilona Hallikainen ◽  
Tuomas Selander ◽  
Soili Törmälehto ◽  
Saku Väätäinen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cohort Study ◽  
Neuropsychiatric Symptoms

scholarly journals Religiosity and quality of life of individuals with Alzheimer’s disease and of caregivers: Relationship with clinical aspects

2020 ◽  
Vol 14 (1) ◽  
pp. 69-74
Author(s):  
Gloria Maria A.S. Tedrus ◽  
Lineu Correa Fonseca ◽  
Julio Cesar Bredas Ciancaglio ◽  
Gabriela Scartezini Mônico ◽  
Carolina Zamperi
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Performance ◽  
Neuropsychiatric Symptoms ◽  
Clinical Aspects ◽  
Intrinsic Religiosity

ABSTRACT There are few studies on the religiosity of people with Alzheimer’s disease (PwAD) and caregivers, relation with quality of life (QoL) and clinical aspects. Objective: To assess the religiosity and QoL of 39 PwAD and their caregivers; to compare perceived QoL and religiosity of the PwAD with those of their caregivers; to associate QoL and religiosity with the presence of neuropsychiatric symptoms, and depression with cognitive performance of PwAD. Results: Organizational religiosity was greater in caregivers. The AD patients had poorer perceived QoL than their caregivers. Caregiver religiosity correlated with that of the AD patients. Higher intrinsic religiosity was associated with lower occurrence of neuropsychiatric symptoms. Better caregiver QoL correlated with cognitive performance. Lower occurrence of depression correlated with better QoL of the caregivers and AD patients. Conclusion: The religiosity of caregivers was correlated with that of the AD patients. Better QoL and lower religiosity were observed in caregivers when compared with the AD patients. Caregiver religiosity and QoL were associated with neuropsychiatric and cognitive aspects and depression.

scholarly journals Effects of anosognosia and neuropsychiatric symptoms on the quality of life of patients with Alzheimer's disease: a 24-month follow-up study

2015 ◽  
Vol 31 (2) ◽  
pp. 109-119 ◽  
Author(s):  
Josep L. Conde-Sala ◽  
Oriol Turró-Garriga ◽  
Sara Piñán-Hernández ◽  
Cristina Portellano-Ortiz ◽  
Vanesa Viñas-Diez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neuropsychiatric Symptoms ◽  
Follow Up Study

scholarly journals Neuropsychiatric symptoms and quality of life in Spanish patients with Alzheimer’s disease during the COVID‐19 lockdown

2020 ◽  
Vol 27 (9) ◽  
pp. 1744-1747 ◽  
Author(s):  
B. Lara ◽  
A. Carnes ◽  
F. Dakterzada ◽  
I. Benitez ◽  
G. Piñol‐Ripoll
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neuropsychiatric Symptoms

A mentally stimulating activities program for the treatment of neuropsychiatric symptoms in Alzheimer’s disease

2019 ◽  
Vol 18 (4) ◽  
pp. 27-37
Author(s):  
Angie L. Sardina, PhD ◽  
Suzanne Fitzsimmons, MSN, ARNP, GNP ◽  
Catherine M. Hoyt, BA ◽  
Linda L. Buettner, PhD
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Support Group ◽  
Repeated Measures ◽  
Early Stage ◽  
Neuropsychiatric Symptoms ◽  
Cognitive Status ◽  
Control Group

This study evaluated whether a mentally stimulating activities (MSA) program reduced neuropsychiatric symptoms and improved cognitive status and quality of life, as compared to a support group for persons in the early stage of Alzheimer’s disease (AD). This randomized controlled trial included 81 adults (aged 55+), who were randomly assigned to the MSA group (treatment) or a social support group (control). A repeated measures multivariate analysis of variance (MANOVA) identified that MSA participants significantly reduced apathy (p 0.001) and depressive symptoms (p 0.001), as well as improved cognitive status (p 0.001) and quality of life (p 0.001) as compared to the control group. A structured classroom-style MSA program may be a viable and therapeutic intervention to alleviate neuropsychiatric symptoms, and improve cognitive status and quality of life in early-stage AD.

Validación de la escala Quality of Life in Alzheimer’s Disease (QOL-AD) en pacientes mexicanos con demencia tipo Alzheimer, vascular y mixta

2010 ◽  
Vol 51 (02) ◽  
pp. 72 ◽  
Author(s):  
Oscar Rosas Carrasco ◽  
Laura del Pilar Torres Arreola ◽  
María de Guadalupe Guerra Silla ◽  
Sara Torres Castro ◽  
Luis Miguel Gutiérrez Robledo
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease
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