scholarly journals Effects of anosognosia and neuropsychiatric symptoms on the quality of life of patients with Alzheimer's disease: a 24-month follow-up study

2015 ◽  
Vol 31 (2) ◽  
pp. 109-119 ◽  
Author(s):  
Josep L. Conde-Sala ◽  
Oriol Turró-Garriga ◽  
Sara Piñán-Hernández ◽  
Cristina Portellano-Ortiz ◽  
Vanesa Viñas-Diez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neuropsychiatric Symptoms ◽  
Follow Up Study

scholarly journals Impact of Alzheimer’s disease on the family caregiver’s long-term quality of life: results from an ALSOVA follow-up study

2015 ◽  
Vol 25 (3) ◽  
pp. 687-697 ◽  
Author(s):  
Tarja H. Välimäki ◽  
Janne A. Martikainen ◽  
Kristiina Hongisto ◽  
Saku Väätäinen ◽  
Harri Sintonen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Follow Up Study ◽  
The Family

Proxy-rated quality of life in Alzheimer's disease: a three-year longitudinal study

2011 ◽  
Vol 24 (1) ◽  
pp. 82-89 ◽  
Author(s):  
Asmus Vogel ◽  
Suvosree Bhattacharya ◽  
Frans B. Waldorff ◽  
Gunhild Waldemar
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Primary Caregivers ◽  
Individual Variations ◽  
Home Living ◽  
State Examination ◽  
Eq Vas

ABSTRACTBackground: The study investigated the change in proxy rated quality of life (QoL) of a large cohort of home living patients with Alzheimer's disease (AD) over a period of 36 months.Methods: The sample consisted of 102 patients with mild AD and their primary caregivers from the Danish Alzheimer's Disease Intervention Study. QoL was assessed with the proxy-rated (primary caregivers) Quality of Life in Alzheimer Disease scale (QOL-AD) and the EuroQuol Visual Analogue Scale (EQ-VAS) scale. The Cornell Scale for Depression in Dementia (CSDD), Alzheimer's Disease Cooperative Study, Activities of Daily living Inventory (ADCS-ADL), Mini-Mental State Examination (MMSE) and Neuropsychiatric Inventory (NPI-Q) were also applied. Evaluations were conducted at baseline and at 12 and 36 months follow-up.Results: There was a significant decline in mean QoL assessed by both the QOL-AD and the EQ-VAS (p < 0.001). There were vast individual differences in the QoL scores on both scales at 12 and 36 months’ follow-up. Mean change from baseline in QOL-AD was significantly associated with change in CSDD, ADCS-ADL and MMSE scores at 12 months and with ADCS-ADL score at 36 months.Conclusion: QoL is a subjective concept and may not be influenced by the degree of cognitive dysfunction. Future studies should investigate the factors for individual variations in order to understand the nature of change of QoL in AD and the wide variation in QoL scores over time.

scholarly journals Effects of cognitive stimulation on neuropsychiatric symptoms in elderly with Alzheimer's disease: A systematic review

2016 ◽  
Vol 10 (3) ◽  
pp. 178-184 ◽  
Author(s):  
Raiana Lídice Mór Fukushima ◽  
Elisangela Gisele do Carmo ◽  
Renata do Valle Pedroso ◽  
Pollyanna Natalia Micali ◽  
Paula Secomandi Donadelli ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Elderly Patients ◽  
Neuropsychiatric Symptoms ◽  
Cognitive Stimulation ◽  
Controlled Trials ◽  
Inclusion Criteria

ABSTRACT Introduction: Neuropsychiatric symptoms are frequent in Alzheimer's disease and negatively affect patient quality of life. Objective: To assess the effectiveness of cognitive stimulation on neuropsychiatric symptoms in elderly patients with Alzheimer's disease. Methods: The included articles were reviewed between December 2015 and June 2016, and the inclusion criteria were: (1) studies involving older adults diagnosed with Alzheimer's disease; (2) studies published in English, Spanish or Portuguese; (3) studies that determined the effect of cognitive stimulation on neuropsychiatric symptoms in elderly patients with Alzheimer's disease; (4) controlled trials. Results: Out of the total 722, 9 articles matched the inclusion criteria. Depression, apathy and anxiety were the most frequent symptoms. Conclusion: Studies reported significant results post-treatment, suggesting cognitive stimulation can be effective for these neuropsychiatric symptoms, thus improving the quality of life of Alzheimer's disease patients and their caregivers.

Genetics of neuropsychiatric symptoms in patients with Alzheimer's disease: A 1‐year follow‐up study

2020 ◽  
Vol 74 (12) ◽  
pp. 645-651 ◽  
Author(s):  
Mei‐Feng Huang ◽  
Wei‐Ju Lee ◽  
Yi‐Chun Yeh ◽  
Yi‐Chu Liao ◽  
Shuu‐Jiun Wang ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Neuropsychiatric Symptoms ◽  
Follow Up Study

Determinants of quality of life in Alzheimer's disease: perspective of patients, informal caregivers, and professional caregivers

2012 ◽  
Vol 24 (11) ◽  
pp. 1805-1815 ◽  
Author(s):  
Maria Gómez-Gallego ◽  
Jesus Gómez-Amor ◽  
Juan Gómez-García
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Medical Condition ◽  
Neuropsychiatric Symptoms ◽  
Chronic Medical Condition ◽  
Psychotic Symptoms ◽  
Sources Of Information ◽  
Healthcare Staff

AbstractBackground: Alzheimer's disease (AD) is a chronic medical condition with symptoms that compromise patients’ quality of life (QoL). The identification of the factor predicting QoL in AD is essential to develop more effective interventions. Recent research suggests that these factors could be different for the distinct informants. This study explores the QoL predictors considering three different sources of information: patients, caregivers, and healthcare staff.Methods: In this cross-sectional study, a sample of 102 patients, their primary caregivers, and 15 members of the healthcare staff evaluated patients’ QoL (QoL-AD Scale). Patients’ and caregivers’ demographic and clinical data (cognitive function, neuropsychiatric symptoms, depression, and caregivers’ burden) were considered as QoL predictors.Results: In multivariate-adjusted linear regression analyses, we observed that patients’ ratings were mainly affected by their mood whereas caregivers’ ratings were also negatively influenced by patients’ irritability and burden. According to staff ratings, both psychotic symptoms and neuroleptics were associated with lower QoL.Conclusions: Our findings suggest that depression is the main variable related to patients’ QoL and that more careful management of neuropsychiatric disorders is necessary. Both proxies’ ratings are not equivalent to patients’ reports in terms of predictors but they are complementary. Thus, a thorough QoL assessment should consider separately the perspective of the different informants.

Quality of Life in relation to neuropsychiatric symptoms in Alzheimer's disease: 5-year prospective ALSOVA cohort study

2017 ◽  
Vol 33 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Kristiina Hongisto ◽  
Ilona Hallikainen ◽  
Tuomas Selander ◽  
Soili Törmälehto ◽  
Saku Väätäinen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cohort Study ◽  
Neuropsychiatric Symptoms

scholarly journals Neuropsychiatric symptoms predict change in quality of life of Alzheimer disease patients: A two-year follow-up study

2009 ◽  
Vol 63 (3) ◽  
pp. 374-384 ◽  
Author(s):  
Hiroshi Tatsumi ◽  
Shutaro Nakaaki ◽  
Katsuyoshi Torii ◽  
Yoshihiro Shinagawa ◽  
Norio Watanabe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer Disease ◽  
Neuropsychiatric Symptoms ◽  
Follow Up Study

scholarly journals Religiosity and quality of life of individuals with Alzheimer’s disease and of caregivers: Relationship with clinical aspects

2020 ◽  
Vol 14 (1) ◽  
pp. 69-74
Author(s):  
Gloria Maria A.S. Tedrus ◽  
Lineu Correa Fonseca ◽  
Julio Cesar Bredas Ciancaglio ◽  
Gabriela Scartezini Mônico ◽  
Carolina Zamperi
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Performance ◽  
Neuropsychiatric Symptoms ◽  
Clinical Aspects ◽  
Intrinsic Religiosity

ABSTRACT There are few studies on the religiosity of people with Alzheimer’s disease (PwAD) and caregivers, relation with quality of life (QoL) and clinical aspects. Objective: To assess the religiosity and QoL of 39 PwAD and their caregivers; to compare perceived QoL and religiosity of the PwAD with those of their caregivers; to associate QoL and religiosity with the presence of neuropsychiatric symptoms, and depression with cognitive performance of PwAD. Results: Organizational religiosity was greater in caregivers. The AD patients had poorer perceived QoL than their caregivers. Caregiver religiosity correlated with that of the AD patients. Higher intrinsic religiosity was associated with lower occurrence of neuropsychiatric symptoms. Better caregiver QoL correlated with cognitive performance. Lower occurrence of depression correlated with better QoL of the caregivers and AD patients. Conclusion: The religiosity of caregivers was correlated with that of the AD patients. Better QoL and lower religiosity were observed in caregivers when compared with the AD patients. Caregiver religiosity and QoL were associated with neuropsychiatric and cognitive aspects and depression.

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