“Click” chemistry-based surface modification of poly(dimethylsiloxane) for protein separation in a microfluidic chip

2010 ◽  
Vol 31 (18) ◽  
pp. 3129-3136 ◽  
Author(s):  
Zhaowei Zhang ◽  
Xiaojun Feng ◽  
Fei Xu ◽  
Xin Liu ◽  
Bi-Feng Liu
Keyword(s):  
Surface Modification ◽  
Click Chemistry ◽  
Microfluidic Chip ◽  
Protein Separation

Sulfonium alkylation followed by ‘click’ chemistry for facile surface modification of proteins and tobacco mosaic virus

2009 ◽  
Vol 50 (7) ◽  
pp. 759-762 ◽  
Author(s):  
Long Yi ◽  
Jie Shi ◽  
Shuang Gao ◽  
Shibo Li ◽  
Congwei Niu ◽  
...  
Keyword(s):  
Surface Modification ◽  
Tobacco Mosaic Virus ◽  
Click Chemistry ◽  
Mosaic Virus

scholarly journals Magnetic Beads Actuating and Sensing by Light Addressability

Proceedings ◽  
2018 ◽  
Vol 2 (13) ◽  
pp. 1019
Author(s):  
Yu-Ping Chen ◽  
Hsin-Yin Peng ◽  
Jia-Long Hong ◽  
Min-Hsien Wu ◽  
Chia-Ming Yang
Keyword(s):  
Surface Modification ◽  
Microfluidic Chip ◽  
Sensor Array ◽  
Magnetic Beads ◽  
High Potential ◽  
Micro Particles ◽  
Ito Glass ◽  
Proper Operation ◽  
2D Images ◽  
Sensing Performance

Micro particles and nanoparticles applied in microfluidics became a popular direction to improve biochip performance. Magnetic beads are the well-studied carriers including manipulation and surface modification, which could be easily to apply in biosensor development. A new methodology combined the actuators and sensor in the same chip all trigged by illumination is proposed in this study. A microfluidic chip with a-Si:H layer and ITO/glass with proper operation could be used to collect magnetic beads firstly and then following the optoelectrical measurement. In the meantime, 2D images for clusters of magnetic beads can be easily achieved with the addressable illumination. This proposed platform could own the high potential for a sensor array with better sensing performance.

Innovative Laser Machining and Surface Modification for Plastic Microfluidic Chip

2002 ◽  
pp. 407-409 ◽  
Author(s):  
Ji-Yen Cheng ◽  
Kai-Hsiung Hsu ◽  
Cheng-Wey Wei ◽  
Tai-Horng Young
Keyword(s):  
Surface Modification ◽  
Microfluidic Chip ◽  
Laser Machining

A Smart Surface in a Microfluidic Chip for Controlled Protein Separation

2007 ◽  
Vol 13 (18) ◽  
pp. 5113-5120 ◽  
Author(s):  
Li Mu ◽  
Ying Liu ◽  
Shaoyu Cai ◽  
Jilie Kong
Keyword(s):  
Microfluidic Chip ◽  
Protein Separation ◽  
Smart Surface

Surface Modification of Tobacco Mosaic Virus with “Click” Chemistry

ChemBioChem ◽  
2008 ◽  
Vol 9 (4) ◽  
pp. 519-523 ◽  
Author(s):  
Michael A. Bruckman ◽  
Gagandeep Kaur ◽  
L. Andrew Lee ◽  
Fang Xie ◽  
Jennifer Sepulveda ◽  
...  
Keyword(s):  
Surface Modification ◽  
Tobacco Mosaic Virus ◽  
Click Chemistry ◽  
Mosaic Virus

Surface Modification of Nanoporous 1,2-Polybutadiene by Atom Transfer Radical Polymerization or Click Chemistry

Langmuir ◽  
2010 ◽  
Vol 26 (3) ◽  
pp. 2008-2013 ◽  
Author(s):  
Fengxiao Guo ◽  
Katja Jankova ◽  
Lars Schulte ◽  
Martin E. Vigild ◽  
Sokol Ndoni
Keyword(s):  
Surface Modification ◽  
Atom Transfer Radical Polymerization ◽  
Click Chemistry ◽  
Radical Polymerization ◽  
Atom Transfer

A Porous Microfluidic Chip for Protein Extraction Based on Solid Phase Extraction Method

2011 ◽  
Vol 483 ◽  
pp. 297-300 ◽  
Author(s):  
Xing Chen ◽  
Da Fu Cui ◽  
Lu Lu Zhang ◽  
Hui Li ◽  
Jian Hai Sun ◽  
...  
Keyword(s):  
Surface Modification ◽  
Porous Silicon ◽  
Solid Phase Extraction ◽  
Microfluidic Chip ◽  
Protein Extraction ◽  
Solid Phase ◽  
Electrochemical Etching ◽  
Rectangular Channel ◽  
Porous Matrix ◽  
Phase Extraction

Based on the principle of solid phase extraction (SPE) and the special immunoreaction, a microfluidic chip integrated with porous matrix was developed for protein extraction. Porous matrix was achieved by electrochemical etching silicon in a HF/ethanol mixture, which was coated on the wall of the rectangular channel of the microchip to provide a surface-enlarging matrix. The surface morphology of the bare porous silicon and the porous silicon modified with the protein has been characterized by SEM. Non-porous chip and porous chip were used to extract protein. Compared with non-porous matrix, the porous matrix achieved higher extracted efficiency of protein. Then two methods of surface modification were employed on porous matrix for protein extraction. The surface modification with Protein A could extract more protein with less non-special absorption. Evaluation of the structure of the solid phase matrix and the surface modification process in the microfluidic chip, the porous microfluidic chip is able to be suitable for incorporation into micro total analysis system (μTAS).

Surface modification of polypropylene macroporous membrane by marrying RAFT polymerization with click chemistry

2012 ◽  
Vol 421-422 ◽  
pp. 60-68 ◽  
Author(s):  
Xiu-Min Wu ◽  
Li-Li Wang ◽  
Yun Wang ◽  
Jia-Shan Gu ◽  
Hai-Yin Yu
Keyword(s):  
Surface Modification ◽  
Click Chemistry ◽  
Raft Polymerization
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