Improvements on the electrokinetic injection technique for microfluidic chips

2006 ◽  
Vol 27 (24) ◽  
pp. 4970-4981 ◽  
Author(s):  
Chien-Hsien Wu ◽  
Ruey-Jen Yang
2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Ji Won Ha

We recently reported acupuncture sample injection that leads to reproducible injection of nL-scale sample segments into a polydimethylsiloxane (PDMS) microchannel for microchip capillary electrophoresis. The advantages of the acupuncture injection in microchip capillary electrophoresis include capability of minimizing sample loss and voltage control hardware and capability of introducing sample plugs into any desired position of a microchannel. However, the challenge in the previous study was to achieve reproducible, pL-scale sample injections into PDMS microchannels. In the present study, we introduce an acupuncture injection technique combined with electrokinetic injection (AICEI) technique to inject pL-scale sample segments for microchip capillary electrophoresis. We carried out the capillary zone electrophoresis (CZE) separation of FITC and fluorescein, and the mixture of 10 μM FITC and 10 μM fluorescein was separated completely by using the AICEI method.


2002 ◽  
Vol 74 (19) ◽  
pp. 5084-5091 ◽  
Author(s):  
L.-M. Fu ◽  
R.-J. Yang ◽  
G.-B. Lee ◽  
H.-H. Liu

2006 ◽  
Vol 505-507 ◽  
pp. 409-414
Author(s):  
Yao Nan Wang ◽  
Chiufeng Lin ◽  
S.T. Wu ◽  
C.L. Chang ◽  
H.T. Chen ◽  
...  

This paper presents an experimental investigation on the use of high-resolution injection techniques to deliver sample plugs within electrophoresis microchips. Two novel injection microfluidic chips are proposed, which employ conventional cross-shaped and U-shaped injection system combined with an expander to deliver high-quality sample plugs for detection in separation channel. The valving characteristics on microfluidic devices are controlled through appropriate manipulations of the electric potential strengths during the sample injection and separation steps. These novel injection techniques developed in this study has an exciting potential for use in high-quality, high-throughput chemical analysis applications and in many other applications throughout the field of micro-total-analysis systems.


2014 ◽  
Vol 39 (10) ◽  
pp. 6851-6862 ◽  
Author(s):  
Hossein Moayedi ◽  
Khairul Anuar Kassim ◽  
Sina Kazemian ◽  
Mehdi Raftari ◽  
Mehdi Mokhberi

1951 ◽  
Vol 17 (2) ◽  
pp. 209-223 ◽  
Author(s):  
R.O. Holmes ◽  
W.V. Lovitt

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 795-P
Author(s):  
KATHARINE D. BARNARD ◽  
EDWARD T. MAHONEY ◽  
DIDIER MOREL ◽  
STANISLAV GLEZER
Keyword(s):  

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