Determination of enantiomeric purity of a novel COX-2 anti-inflammatory drug by capillary electrophoresis using single and dual cyclodextrin systems

Carlos Pérez-Maseda; Carme Calvet; Rosa Cuberes; Jordi Frigola

doi:10.1002/elps.200390182

Determination of enantiomeric purity of a novel COX-2 anti-inflammatory drug by capillary electrophoresis using single and dual cyclodextrin systems

Electrophoresis ◽

10.1002/elps.200390182 ◽

2003 ◽

Vol 24 (9) ◽

pp. 1416-1421 ◽

Cited By ~ 10

Author(s):

Carlos Pérez-Maseda ◽

Carme Calvet ◽

Rosa Cuberes ◽

Jordi Frigola

Keyword(s):

Capillary Electrophoresis ◽

Enantiomeric Purity ◽

Inflammatory Drug ◽

Cox 2 ◽

Anti Inflammatory

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A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: the case of nimesulide, a Cox-2 selective nonsteroidal anti-inflammatory drug in the dog

Journal of Veterinary Pharmacology and Therapeutics ◽

10.1046/j.1365-2885.2001.00304.x ◽

2001 ◽

Vol 24 (1) ◽

pp. 43-55 ◽

Cited By ~ 40

Author(s):

P. L. Toutain ◽

C. C. Cester ◽

T. Haak ◽

V. Laroute

Keyword(s):

Dosage Regimen ◽

Dose Titration ◽

Inflammatory Drug ◽

Cox 2 ◽

Anti Inflammatory ◽

Pharmacodynamic Approach

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Determination of the novel non-steroidal anti-inflammatory drug lornoxicam and its main metabolite in plasma and synovial fluid

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/s0378-4347(97)00597-5 ◽

1998 ◽

Vol 707 (1-2) ◽

pp. 151-159 ◽

Cited By ~ 24

Author(s):

S Radhofer-Welte ◽

P Dittrich

Keyword(s):

Synovial Fluid ◽

The Novel ◽

Main Metabolite ◽

Inflammatory Drug ◽

Anti Inflammatory

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Development and validation of a capillary electrophoresis method for the enantiomeric purity determination of SLV307, a basic potential antipsychotic compound

Electrophoresis ◽

10.1002/elps.200406022 ◽

2004 ◽

Vol 25 (16) ◽

pp. 2854-2859 ◽

Cited By ~ 7

Author(s):

Pim G. Muijselaar ◽

Norbert G. F. M. Lammers ◽

Thijs K. Gerding

Keyword(s):

Capillary Electrophoresis ◽

Enantiomeric Purity ◽

Purity Determination ◽

Capillary Electrophoresis Method ◽

Electrophoresis Method ◽

Development And Validation

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Quantitative determination of new anti-inflammatory drug indomenthyl and its metabolite in rabbit plasma by HPLC–MS/MS

Analytical Methods ◽

10.1039/d1ay01220g ◽

2021 ◽

Author(s):

Klim Leonov ◽

Arina Bykova ◽

Vladimir Bykov ◽

Darya Vishenkova ◽

Olga Lipskikh ◽

...

Keyword(s):

Quantitative Determination ◽

Analgesic Activity ◽

Rabbit Plasma ◽

Inflammatory Drug ◽

Anti Inflammatory

Background: Indomenthyl is an innovative anti-inflammatory drug with a high analgesic activity. Indomenthyl releases indomethacin under the influence of neutrophil esterases in the inflammation focus. Methodology/results: This research is aimed...

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Cathodic adsorptive stripping voltammetric determination of the anti-inflammatory drug indomethacin

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/s0731-7085(98)00111-3 ◽

1999 ◽

Vol 18 (6) ◽

pp. 1005-1012 ◽

Cited By ~ 17

Author(s):

Azza M.M Ali

Keyword(s):

Voltammetric Determination ◽

Inflammatory Drug ◽

Anti Inflammatory

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The Effectiveness of a Weak Opioid Medication versus a Cyclo-Oxygenase-2 (COX-2) Selective Non-Steroidal Anti-Inflammatory Drug in Treating Flare-Up of Chronic Low-Back Pain: Results from Two Randomized, Double-Blind, 6-Week Studies

Journal of International Medical Research ◽

10.1177/147323000903700615 ◽

2009 ◽

Vol 37 (6) ◽

pp. 1789-1802 ◽

Cited By ~ 32

Author(s):

JB O'Donnell ◽

EF Ekman ◽

WM Spalding ◽

P Bhadra ◽

D McCabe ◽

...

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Chronic Low Back Pain ◽

Low Back ◽

Double Blind ◽

Opioid Medication ◽

Inflammatory Drug ◽

Cox 2 ◽

Anti Inflammatory ◽

Weak Opioid

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Carboxyl-functionalized graphene oxide-modified electrode for the electrochemical determination of nonsteroidal anti-inflammatory drug diclofenac

Ionics ◽

10.1007/s11581-014-1161-9 ◽

2014 ◽

Vol 21 (1) ◽

pp. 231-238 ◽

Cited By ~ 39

Author(s):

Chelladurai Karuppiah ◽

Srikanth Cheemalapati ◽

Shen-Ming Chen ◽

Selvakumar Palanisamy

Keyword(s):

Graphene Oxide ◽

Modified Electrode ◽

Electrochemical Determination ◽

Functionalized Graphene ◽

Functionalized Graphene Oxide ◽

Inflammatory Drug ◽

Anti Inflammatory

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Meloxicam:a selective COX-2 inhibitor non-steroidal anti-inflammatory drug

Expert Opinion on Investigational Drugs ◽

10.1517/13543784.6.3.321 ◽

1997 ◽

Vol 6 (3) ◽

pp. 321-334 ◽

Cited By ~ 7

Author(s):

Manfred Schattenkirchner

Keyword(s):

Inflammatory Drug ◽

Cox 2 ◽

Anti Inflammatory

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Enantiomeric purity determination of tamsulosin by capillary electrophoresis using cyclodextrins and a polyacrylamide-coated capillary

Il Farmaco ◽

10.1016/j.farmac.2005.07.005 ◽

2005 ◽

Vol 60 (10) ◽

pp. 834-839 ◽

Cited By ~ 8

Author(s):

Andrea Kavalírová ◽

Marie Pospíšilová ◽

Rolf Karlíček

Keyword(s):

Capillary Electrophoresis ◽

Enantiomeric Purity ◽

Purity Determination

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Determination of the enantiomeric purity of 2-(2′-carboxy-3′-phenylcyclopropyl)glycines by chiral capillary electrophoresis

Chromatographia ◽

10.1007/bf02491204 ◽

2001 ◽

Vol 54 (7-8) ◽

pp. 485-488

Author(s):

R. Gotti ◽

B. Natalini ◽

R. Pomponio ◽

V. Cavrini

Keyword(s):

Capillary Electrophoresis ◽

Enantiomeric Purity ◽

Chiral Capillary Electrophoresis

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