Quantitative determination of new anti-inflammatory drug indomenthyl and its metabolite in rabbit plasma by HPLC–MS/MS

2021 ◽  
Author(s):  
Klim Leonov ◽  
Arina Bykova ◽  
Vladimir Bykov ◽  
Darya Vishenkova ◽  
Olga Lipskikh ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Analgesic Activity ◽  
Rabbit Plasma ◽  
Inflammatory Drug ◽  
Anti Inflammatory

Background: Indomenthyl is an innovative anti-inflammatory drug with a high analgesic activity. Indomenthyl releases indomethacin under the influence of neutrophil esterases in the inflammation focus. Methodology/results: This research is aimed...

The development of technology for obtaining a dry extract of oak bark

2021 ◽  
pp. 38-45
Author(s):  
N.I. Dubovskaya ◽  
M.S. Zolotareva ◽  
A.V. Panov ◽  
S.A. Kedik
Keyword(s):  
Quantitative Determination ◽  
Bark Extract ◽  
Dry Extract ◽  
Inflammatory Agent ◽  
Anti Inflammatory

The article presents the development of a technology for obtaining a dry extract of oak bark and the quantitative determination of tannins in it. Oak bark extract is used medicinally as a local anti-inflammatory agent. The development of a technology for obtaining a dry extract will provide more opportunities for its use.

scholarly journals Antinociceptive and anti-inflammatory activities of the Jatropha isabellei dichloromethane fraction and isolation and quantitative determination of jatrophone by UFLC-DAD

2017 ◽  
Vol 55 (1) ◽  
pp. 1215-1222 ◽  
Author(s):  
Janaina Kieling Fröhlich ◽  
Taciane Stein ◽  
Layzon Antônio da Silva ◽  
Maique Weber Biavatti ◽  
Carlos Rogério Tonussi ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Anti Inflammatory

Quantitative determination of microbicidal spermicide ‘nonoxynol-9’ in rabbit plasma and vaginal fluid using LC–ESI–MS/MS: Application to pharmacokinetic study

2014 ◽  
Vol 965 ◽  
pp. 127-132 ◽  
Author(s):  
Yashpal S. Chhonker ◽  
Hardik Chandasana ◽  
Veenu Bala ◽  
Lokesh Kumar ◽  
Vishnu Lal Sharma ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Pharmacokinetic Study ◽  
Vaginal Fluid ◽  
Rabbit Plasma ◽  
Esi Ms
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