Intramuscular pH modulates glutamate-evoked masseter muscle pain magnitude in humans

2015 ◽  
Vol 20 (1) ◽  
pp. 106-115 ◽  
Author(s):  
H. Sato ◽  
E.E. Castrillon ◽  
B.E. Cairns ◽  
K.H. Bendixen ◽  
K. Wang ◽  
...  
Keyword(s):  
Muscle Pain ◽  
Masseter Muscle ◽  
Intramuscular Ph

Reorganization of Masseter and Temporalis Muscle Single Motor Unit Activity During Experimental Masseter Muscle Pain

2020 ◽  
Vol 34 (1) ◽  
pp. 40-52
Author(s):  
Polyana Ferreira ◽  
Isbel Sandoval ◽  
Terry Whittle ◽  
Yalda Mojaver ◽  
Greg Murray
Keyword(s):  
Motor Unit ◽  
Unit Activity ◽  
Muscle Pain ◽  
Masseter Muscle ◽  
Temporalis Muscle ◽  
Single Motor Unit ◽  
Single Motor ◽  
Motor Unit Activity

scholarly journals Assessment of the Potential Role of Muscle Spindle Mechanoreceptor Afferents in Chronic Muscle Pain in the Rat Masseter Muscle

PLoS ONE ◽  
2010 ◽  
Vol 5 (6) ◽  
pp. e11131 ◽  
Author(s):  
James P. Lund ◽  
Somayeh Sadeghi ◽  
Tuija Athanassiadis ◽  
Nadia Caram Salas ◽  
François Auclair ◽  
...  
Keyword(s):  
Muscle Spindle ◽  
Muscle Pain ◽  
Masseter Muscle ◽  
Potential Role ◽  
Chronic Muscle Pain

Intramuscular Temperature Modulates Glutamate-Evoked Masseter Muscle Pain Intensity in Humans

2015 ◽  
Vol 29 (2) ◽  
pp. 158-167 ◽  
Author(s):  
Hitoshi Sato ◽  
Eduardo Castrillon ◽  
Brian Cairns ◽  
Karina Bendixen ◽  
Kelun Wang ◽  
...  
Keyword(s):  
Pain Intensity ◽  
Muscle Pain ◽  
Masseter Muscle ◽  
Intramuscular Temperature

Entropy of Masseter Muscle Pain Sensitivity: A New Technique for Pain Assessment

2017 ◽  
Vol 31 (1) ◽  
pp. 87-94 ◽  
Author(s):  
Eduardo Castrillon ◽  
Fernando Exposto ◽  
Hitoshi Sato ◽  
Tomohiro Tanosoto ◽  
Taro Arima ◽  
...  
Keyword(s):  
Pain Assessment ◽  
Muscle Pain ◽  
Masseter Muscle ◽  
Pain Sensitivity ◽  
New Technique ◽  
A New Technique

Activation of Peripheral NMDA Receptors Contributes to Human Pain and Rat Afferent Discharges Evoked by Injection of Glutamate into the Masseter Muscle

2003 ◽  
Vol 90 (4) ◽  
pp. 2098-2105 ◽  
Author(s):  
Brian E. Cairns ◽  
Peter Svensson ◽  
Kelun Wang ◽  
Steen Hupfeld ◽  
Thomas Graven-Nielsen ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Nmda Receptors ◽  
Hypertonic Saline ◽  
Muscle Pain ◽  
Masseter Muscle ◽  
Human Subjects ◽  
Nmda Receptor Antagonists ◽  
Receptor Antagonists ◽  
Human Experiments ◽  
Masticatory Muscle Pain

Peripheral N-methyl-d-aspartate (NMDA) receptors are found in deep tissues and may play a role in deep tissue pain. Injection of the endogenous NMDA receptor agonist glutamate into the masseter muscle excites deep craniofacial afferent fibers in rats and evokes pain in human subjects. It is not clear whether peripheral NMDA receptors play a role in these effects of glutamate. Accordingly, the effect of NMDA on afferent activity as well as the effect of locally administered NMDA receptor antagonists on glutamate-evoked afferent discharges in acutely anesthetized rats and muscle pain in human subjects was examined. Injection of NMDA into the masseter muscle evoked afferent discharges in a concentration-related manner. It was found that the NMDA receptor antagonists 2-amino-5-phosphonvalerate (APV, 10 mM), ketamine (10 mM), and dextromethorphan (40 mM) significantly decreased glutamate-evoked afferent discharges. The effects of APV and ketamine, but not dextromethorphan, were selective for glutamate-evoked afferent discharges and did not affect hypertonic saline-evoked afferent discharges. In human experiments, it was found that 10 mM ketamine decreased glutamate-evoked muscle pain but had no effect on hypertonic saline-evoked muscle pain. These results indicate that injection of glutamate into the masseter muscle evokes afferent discharges in rats and muscle pain in humans in part through activation of peripheral NMDA receptors. It is conceivable that activation of peripheral NMDA receptors may contribute to masticatory muscle pain and that peripherally acting NMDA receptor antagonists could prove to be effective analgesics for this type of pain.

scholarly journals Does induced masseter muscle pain affect integrated jaw-neck movements similarly in men and women?

2016 ◽  
Vol 124 (6) ◽  
pp. 546-553 ◽  
Author(s):  
Birgitta Wiesinger ◽  
Birgitta Häggman-Henrikson ◽  
Fredrik Hellström ◽  
Erling Englund ◽  
Anders Wänman
Keyword(s):  
Muscle Pain ◽  
Masseter Muscle ◽  
Men And Women ◽  
Pain Affect
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