Intramuscular Temperature Modulates Glutamate-Evoked Masseter Muscle Pain Intensity in Humans

2015 ◽  
Vol 29 (2) ◽  
pp. 158-167 ◽  
Author(s):  
Hitoshi Sato ◽  
Eduardo Castrillon ◽  
Brian Cairns ◽  
Karina Bendixen ◽  
Kelun Wang ◽  
...  
2008 ◽  
Vol 18 (2) ◽  
pp. 103-115 ◽  
Author(s):  
Rachael C. Gliottoni ◽  
Robert W. Motl

This experiment examined the effect of a moderate dose of caffeine on perceptions of leg-muscle pain during a bout of high-intensity cycling exercise and the role of anxiety sensitivity in the hypoalgesic effect of caffeine on muscle pain during exercise. Sixteen college-age women ingested caffeine (5 mg/kg body weight) or a placebo and 1 hr later completed 30 min of cycling on an ergometer at 80% of peak aerobic capacity. The conditions were completed in a counterbalanced order, and perceptions of leg-muscle pain were recorded during the bouts of exercise. Caffeine resulted in a large reduction in leg-muscle pain-intensity ratings compared with placebo (d = −0.95), and the reduction in leg-muscle pain-intensity ratings was larger in those with lower anxiety-sensitivity scores than those with higher anxiety-sensitivity scores (d = −1.28 based on a difference in difference scores). The results support that caffeine ingestion has a large effect on reducing leg-muscle pain during high-intensity exercise, and the effect is moderated by anxiety sensitivity.


2014 ◽  
Vol 94 (4) ◽  
pp. 477-489 ◽  
Author(s):  
Jorge Fuentes ◽  
Susan Armijo-Olivo ◽  
Martha Funabashi ◽  
Maxi Miciak ◽  
Bruce Dick ◽  
...  

Background Physical therapy influences chronic pain by means of the specific ingredient of an intervention as well as contextual factors including the setting and therapeutic alliance (TA) between provider and patient. Objective The purpose of this study was to compare the effect of enhanced versus limited TA on pain intensity and muscle pain sensitivity in patients with chronic low back pain (CLBP) receiving either active or sham interferential current therapy (IFC). Design An experimental controlled study with repeated measures was conducted. Participants were randomly divided into 4 groups: (1) AL (n=30), which included the application of active IFC combined with a limited TA; (2) SL (n=29), which received sham IFC combined with a limited TA; (3) AE (n=29), which received active IFC combined with an enhanced TA; and (4) SE (n=29), which received sham IFC combined with an enhanced TA. Methods One hundred seventeen individuals with CLBP received a single session of active or sham IFC. Measurements included pain intensity as assessed with a numerical rating scale (PI-NRS) and muscle pain sensitivity as assessed via pressure pain threshold (PPT). Results Mean differences on the PI-NRS were 1.83 cm (95% CI=14.3–20.3), 1.03 cm (95% CI=6.6–12.7), 3.13 cm (95% CI=27.2–33.3), and 2.22 cm (95% CI=18.9–25.0) for the AL, SL, AE, and SE groups, respectively. Mean differences on PPTs were 1.2 kg (95% CI=0.7–1.6), 0.3 kg (95% CI=0.2–0.8), 2.0 kg (95% CI=1.6–2.5), and 1.7 kg (95% CI=1.3–2.1), for the AL, SL, AE, and SE groups, respectively. Limitations The study protocol aimed to test the immediate effect of the TA within a clinical laboratory setting. Conclusions The context in which physical therapy interventions are offered has the potential to dramatically improve therapeutic effects. Enhanced TA combined with active IFC appears to lead to clinically meaningful improvements in outcomes when treating patients with CLBP.


2020 ◽  
Vol 34 (1) ◽  
pp. 40-52
Author(s):  
Polyana Ferreira ◽  
Isbel Sandoval ◽  
Terry Whittle ◽  
Yalda Mojaver ◽  
Greg Murray

PLoS ONE ◽  
2010 ◽  
Vol 5 (6) ◽  
pp. e11131 ◽  
Author(s):  
James P. Lund ◽  
Somayeh Sadeghi ◽  
Tuija Athanassiadis ◽  
Nadia Caram Salas ◽  
François Auclair ◽  
...  

2002 ◽  
Vol 18 (6) ◽  
pp. 386-393 ◽  
Author(s):  
Melanie S. Poudevigne ◽  
Patrick J. O'Connor ◽  
Jeffrey D. Pasley

2017 ◽  
Vol 31 (1) ◽  
pp. 87-94 ◽  
Author(s):  
Eduardo Castrillon ◽  
Fernando Exposto ◽  
Hitoshi Sato ◽  
Tomohiro Tanosoto ◽  
Taro Arima ◽  
...  

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