C-C Cross-Coupling Reactions of Organosilanes with Terminal Alkenes and Allylic Acetates Using PdII Catalyst Supported on Starch Coated Magnetic Nanoparticles

2020 ◽  
Vol 2020 (7) ◽  
pp. 878-883
Author(s):  
Debabrata Patra ◽  
Subir Panja ◽  
Amit Saha
Keyword(s):  
Magnetic Nanoparticles ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Terminal Alkenes

scholarly journals Magnetically Recoverable Nanoparticulate Catalysts for Cross-Coupling Reactions: The Dendritic Support Influences the Catalytic Performance

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3345
Author(s):  
Nina V. Kuchkina ◽  
Svetlana A. Sorokina ◽  
Alexey V. Bykov ◽  
Mikhail G. Sulman ◽  
Lyudmila M. Bronstein ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Magnetic Nanoparticles ◽  
Magnetic Separation ◽  
Reaction Times ◽  
Cross Coupling ◽  
Pd Nanoparticles ◽  
Coupling Reactions ◽  
Green Solvents ◽  
Cross Coupling Reactions ◽  
Strong Stabilization

Carbon-carbon cross-coupling reactions are among the most important synthetic tools for the preparation of pharmaceuticals and bioactive compounds. However, these reactions are normally carried out using copper, phosphines, and/or amines, which are poisonous for pharmaceuticals. The use of nanocomposite catalysts holds promise for facilitating these reactions and making them more environmentally friendly. In the present work, the PEGylated (PEG stands for poly(ethylene glycol) pyridylphenylene dendrons immobilized on silica loaded with magnetic nanoparticles have been successfully employed for the stabilization of Pd2+ complexes and Pd nanoparticles. The catalyst developed showed excellent catalytic activity in copper-free Sonogashira and Heck cross-coupling reactions. The reactions proceeded smoothly in green solvents at low palladium loading, resulting in high yields of cross-coupling products (from 80% to 97%) within short reaction times. The presence of magnetic nanoparticles allows easy magnetic separation for repeated use without a noticeable decrease of catalytic activity due to the strong stabilization of Pd species by rigid and bulky dendritic ligands. The PEG dendron periphery makes the catalyst hydrophilic and better suited for green solvents. The minor drop in activity upon the catalyst reuse is explained by the formation of Pd nanoparticles from the Pd2+ species during the catalytic reaction. The magnetic separation and reuse of the nanocomposite catalyst reduces the cost of target products as well as energy and material consumption and diminishes residual contamination by the catalyst. These factors as well as the absence of copper in the catalyst makeup pave the way for future applications of such catalysts in cross-coupling reactions.

Pd/Cu-free Magnetic Cobalt Catalyst for C-N cross Coupling Reactions: Synthesis of Abemaciclib and Fedratinib

2021 ◽  
Author(s):  
Zahra Khorsandi ◽  
Abdol R. Hajipour ◽  
Mohammad R. Sarfjoua ◽  
Rajender S Varma
Keyword(s):  
Magnetic Nanoparticles ◽  
Functional Groups ◽  
Cobalt Catalyst ◽  
Cross Coupling ◽  
Catalyst System ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Nano Catalyst ◽  
Natural Ligands ◽  
Cobalt Species

Herein, the synthesis of a nano-catalyst system comprising magnetic nanoparticles as core and edible natural ligands bearings functional groups for supporting the cobalt species was accomplished. Subsequent to characterization, its...

scholarly journals Copper based on diaminonaphthalene-coated magnetic nanoparticles as robust catalysts for catalytic oxidation reactions and C–S cross-coupling reactions

RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9366-9380
Author(s):  
Nasrin Yarmohammadi ◽  
Mohammad Ghadermazi ◽  
Roya Mozafari
Keyword(s):  
Magnetic Nanoparticles ◽  
Catalytic Oxidation ◽  
High Efficiency ◽  
Cross Coupling ◽  
Organic Reactions ◽  
Coupling Reactions ◽  
Oxidation Reactions ◽  
Cross Coupling Reactions ◽  
Toxic Materials

This green-based catalyst with non-toxic materials and high efficiency is used in organic reactions.

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