scholarly journals Synthesis of a 3′-Deoxy-C -Nucleoside Phosphonate Bearing 9-Deazaadenine as Base Moiety

2018 ◽  
Vol 2018 (47) ◽  
pp. 6657-6664
Author(s):  
Peng Nie ◽  
Elisabetta Groaz ◽  
Steven De Jonghe ◽  
Graciela Andrei ◽  
Piet Herdewijn
Keyword(s):  
Base Moiety

Development of the excimer probe responsible for DNA target bearing the silylated pyrenes at base moiety

2014 ◽  
Vol 24 (18) ◽  
pp. 4372-4375 ◽  
Author(s):  
Tomohisa Moriguchi ◽  
Mayumi Ichimura ◽  
Mitsuhisa Kato ◽  
Kenya Suzuki ◽  
Yuki Takahashi ◽  
...  
Keyword(s):  
Base Moiety

scholarly journals Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety

Tetrahedron ◽  
2019 ◽  
Vol 75 (39) ◽  
pp. 130529 ◽  
Author(s):  
Karel Pomeisl ◽  
Marcela Krečmerová ◽  
Radek Pohl ◽  
Robert Snoeck ◽  
Graciela Andrei
Keyword(s):  
Acyclic Nucleoside Phosphonates ◽  
Acyclic Nucleoside ◽  
Base Moiety

Deamination of the Radical Cation of the Base Moiety of 2′-Deoxycytidine: A Theoretical Study

ChemPhysChem ◽  
2008 ◽  
Vol 9 (8) ◽  
pp. 1195-1203 ◽  
Author(s):  
Vanessa Labet ◽  
André Grand ◽  
Jean Cadet ◽  
Leif A. Eriksson
Keyword(s):  
Radical Cation ◽  
Theoretical Study ◽  
Base Moiety

The Effect of RNA Inactivator(s) Synthesized from Cu2+ and Hydroquinone on Adenine, Cytosine, Guanine, and Uracil

1984 ◽  
Vol 3 (2) ◽  
pp. 199-205
Author(s):  
Asaad N. Masoud ◽  
Moslih I. Al-Moslih ◽  
George R. Dubes
Keyword(s):  
Significant Loss ◽  
The Other ◽  
Viral Rna ◽  
Rna Genome ◽  
Base Moiety

The RNA inactivator(s) synthesized from Cu2+ and hydroquinone reacts with ail four free bases: adenine, cytosine, guanine, and uracil. After 1 day at 23°C, losses of these bases averaged 66%, 39%, 97%, and 25%, respectively. In the controls with neither Cu2+ nor hydroquinone and with either one without the other, there was no significant loss of any of the bases, except for the possibly significant loss (14%) of adenine after incubation with Cu2+ without hydroquinone. L-Histidine, a chelator of Cu2+, protected all four bases against the inactivation. The hypothesis that the chemical target(s) for the inactivator(s) in monoribonucleotides and in the naked viral RNA genome is the base moiety(ies) is discussed.

scholarly journals Structure and photochromic properties of a novel diarylethene containing a 9-fluorenone hydrazone Schiff base moiety

2019 ◽  
Vol 44 (3-4) ◽  
pp. 137-141
Author(s):  
Yuexia Zhuge ◽  
Chunhong Zheng ◽  
Guanming Liao ◽  
Shouzhi Pu
Keyword(s):  
Schiff Base ◽  
Single Crystal ◽  
Diffraction Analysis ◽  
Fatigue Resistance ◽  
Crystalline Phase ◽  
Photochromic Properties ◽  
Single Crystal Diffraction ◽  
Fluorescence Modulation ◽  
High Fluorescence ◽  
Base Moiety

A novel diarylethene containing a 9-fluorenone hydrazone Schiff base moiety is designed and synthesized. The structure is characterized by single-crystal diffraction analysis and it shows excellent photochromism in the single crystalline phase. Moreover, the diarylethene product shows relatively high fluorescence modulation efficiency and good fatigue resistance.

scholarly journals Microbial metabolism of amino alcohols. Biosynthetic utilization of ethanolamine for lipid synthesis by bacteria

1980 ◽  
Vol 186 (1) ◽  
pp. 13-19 ◽  
Author(s):  
S D Shukla ◽  
J M Turner
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Mycobacterium Smegmatis ◽  
Lipid Synthesis ◽  
Erwinia Carotovora ◽  
Radioactive Isotopes ◽  
Growth Media ◽  
Lipid Fractions ◽  
Base Moiety ◽  
Aldehyde Dehydrogenase Activity

1. Ten bacteria utilizing [2-14C]ethanol-2-amine as the sole or major source of nitrogen for growth on glycerol + salts medium incorporated radioactivity into a variety of bacterial substances. A high proportion was commonly found in lipid fractions, particularly in the case of Erwinia carotovora. 2. Detailed studies of [14C]ethanolamine incorporation into lipids by five bacteria, including E. carotovora, showed that all detectable lipids were labelled. Even where phosphatidylethanolamine was the major lipid labelled, radioactivity was predominantly in the fatty acid rather than the base moiety. The labelled fatty acids were identified in each case. 3. The addition of acetate to growth media decreased the incorporation of radioactivity from ethanolamine into both fatty acid and phosphatidyl-base fragments of lipids from all the bacteria except Mycobacterium smegmatis. Experiments with [3H]ethanolamine and [14C]acetate confirmed that unlabelled acetate decreased the incorporation of both radioactive isotopes into lipids, except in the case of M. smegmatis. 4. Enzyme studies suggested one of two metabolic routes between ethanolamine and acetyl-CoA for each of four bacteria. A role for ethanolamine O-phosphate was not obligatory for the incorporation of [14C]ethanolamine into phospholipids, but correlated with CoA-independent aldehyde dehydrogenase activity.

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