Diastereo- and Enantioselective Synthesis of Spiro-Pyrrolidine-Pyr­azolones by Squaramide-Catalyzed Cascade Aza-Michael/Michael Reactions

Jun-Hua Li; Hongliang Wen; Lei Liu; Da-Ming Du

doi:10.1002/ejoc.201600316

Diastereo- and Enantioselective Synthesis of Spiro-Pyrrolidine-Pyrazolones by Squaramide-Catalyzed Cascade Aza-Michael/Michael Reactions

European Journal of Organic Chemistry ◽

10.1002/ejoc.201600316 ◽

2016 ◽

Vol 2016 (14) ◽

pp. 2492-2499 ◽

Cited By ~ 34

Author(s):

Jun-Hua Li ◽

Hongliang Wen ◽

Lei Liu ◽

Da-Ming Du

Keyword(s):

Enantioselective Synthesis ◽

Michael Reactions

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ChemInform Abstract: Asymmetric Michael Reactions: Enantioselective Synthesis of δ- Oxo Acids.

ChemInform ◽

10.1002/chin.199242057 ◽

2010 ◽

Vol 23 (42) ◽

pp. no-no

Author(s):

F. MICHELON ◽

A. POUILHES ◽

N. VAN BAC ◽

N. LANGLOIS

Keyword(s):

Enantioselective Synthesis ◽

Michael Reactions

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ChemInform Abstract: Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5 + 1] Double Michael Reactions.

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10.1002/chin.201228108 ◽

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pp. no-no

Author(s):

Bin Wu ◽

Jian Chen ◽

Mei-Qiu Li ◽

Jin-Xin Zhang ◽

Xiao-Ping Xu ◽

...

Keyword(s):

Enantioselective Synthesis ◽

Michael Reactions

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Enantioselective synthesis of 3-substituted isoindolinones via chiral phase-transfer catalyzed intramolecular aza-Michael reactions

10.3390/ecsoc-17-a033 ◽

2013 ◽

Author(s):

Eric Deniau ◽

Stéphane Lebrun

Keyword(s):

Phase Transfer ◽

Enantioselective Synthesis ◽

Chiral Phase ◽

Michael Reactions

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Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5+1] Double Michael Reactions

European Journal of Organic Chemistry ◽

10.1002/ejoc.201101529 ◽

2012 ◽

Vol 2012 (7) ◽

pp. 1318-1327 ◽

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Keyword(s):

Enantioselective Synthesis ◽

Michael Reactions

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Using Conveniently Designed α-Amino Ketones in Michael Reactions under Iminium Catalysis: Enantioselective Synthesis of γ-Lactams and γ-Amino-δ-keto Esters

Advanced Synthesis & Catalysis ◽

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2013 ◽

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pp. 653-658 ◽

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Keyword(s):

Enantioselective Synthesis ◽

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Michael Reactions

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ChemInform Abstract: Organocatalytic Asymmetric anti-Selective Michael Reactions of Aldehydes and the Sequential Reduction/Lactonization/Pauson-Khand Reaction for the Enantioselective Synthesis of Highly Functionalized Hydropentalenes.

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10.1002/chin.201311137 ◽

2013 ◽

Vol 44 (11) ◽

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Author(s):

Bor-Cherng Hong ◽

Nitin S. Dange ◽

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Keyword(s):

Enantioselective Synthesis ◽

Michael Reactions ◽

Sequential Reduction

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Enantioselective Synthesis of 5,5-Disubstituted Hydantoins by Brønsted Base/H-Bond Catalyst Assisted Michael Reactions of a Design Template

Chemistry - A European Journal ◽

10.1002/chem.201800506 ◽

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Vol 24 (28) ◽

pp. 7217-7227 ◽

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...

Keyword(s):

Enantioselective Synthesis ◽

Michael Reactions ◽

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Mukaiyama–Michael Reactions with Acrolein and Methacrolein: A Catalytic Enantioselective Synthesis of the C17–C28 Fragment of Pectenotoxins

Organic Letters ◽

10.1021/ol203486p ◽

2012 ◽

Vol 14 (4) ◽

pp. 1086-1089 ◽

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Keyword(s):

Enantioselective Synthesis ◽

Michael Reactions

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ChemInform Abstract: Using Conveniently Designed α-Amino Ketones in Michael Reactions under Iminium Catalysis: Enantioselective Synthesis of γ-Lactams and γ-Amino-δ-keto Esters.

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10.1002/chin.201332119 ◽

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Garazi Talavera ◽

Efraim Reyes ◽

Jose L. Vicario ◽

Luisa Carrillo ◽

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Keyword(s):

Enantioselective Synthesis ◽

Keto Esters ◽

Michael Reactions

Download Full-text

Mukaiyama–Michael Reactions with Acrolein and Methacrolein: A Catalytic Enantioselective Synthesis of the C17–C28 Fragment of Pectenotoxins

Organic Letters ◽

10.1021/ol402460b ◽

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Vol 15 (18) ◽

pp. 4916-4916

Author(s):

Eeva K. Kemppainen ◽

Gokarneswar Sahoo ◽

Arto Valkonen ◽

Petri M. Pihko

Keyword(s):

Enantioselective Synthesis ◽

Michael Reactions

Download Full-text

Diastereo- and Enantioselective Synthesis of Spiro-Pyrrolidine-Pyr­azolones by Squaramide-Catalyzed Cascade Aza-Michael/Michael Reactions

ChemInform Abstract: Asymmetric Michael Reactions: Enantioselective Synthesis of δ- Oxo Acids.

ChemInform Abstract: Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5 + 1] Double Michael Reactions.

Enantioselective synthesis of 3-substituted isoindolinones via chiral phase-transfer catalyzed intramolecular aza-Michael reactions

Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5+1] Double Michael Reactions

Using Conveniently Designed α-Amino Ketones in Michael Reactions under Iminium Catalysis: Enantioselective Synthesis of γ-Lactams and γ-Amino-δ-keto Esters

ChemInform Abstract: Organocatalytic Asymmetric anti-Selective Michael Reactions of Aldehydes and the Sequential Reduction/Lactonization/Pauson-Khand Reaction for the Enantioselective Synthesis of Highly Functionalized Hydropentalenes.

Enantioselective Synthesis of 5,5-Disubstituted Hydantoins by Brønsted Base/H-Bond Catalyst Assisted Michael Reactions of a Design Template

Mukaiyama–Michael Reactions with Acrolein and Methacrolein: A Catalytic Enantioselective Synthesis of the C17–C28 Fragment of Pectenotoxins

ChemInform Abstract: Using Conveniently Designed α-Amino Ketones in Michael Reactions under Iminium Catalysis: Enantioselective Synthesis of γ-Lactams and γ-Amino-δ-keto Esters.

Mukaiyama–Michael Reactions with Acrolein and Methacrolein: A Catalytic Enantioselective Synthesis of the C17–C28 Fragment of Pectenotoxins

Diastereo- and Enantioselective Synthesis of Spiro-Pyrrolidine-Pyrazolones by Squaramide-Catalyzed Cascade Aza-Michael/Michael Reactions