Direct visualization of the dynamics of antigen presentation in human cells infected with cytomegalovirus revealed by antibodies mimicking TCR specificity

Oryan Makler; Kfir Oved; Nir Netzer; Dana Wolf; Yoram Reiter

doi:10.1002/eji.200939875

Direct visualization of the dynamics of antigen presentation in human cells infected with cytomegalovirus revealed by antibodies mimicking TCR specificity

European Journal of Immunology ◽

10.1002/eji.200939875 ◽

2010 ◽

Vol 40 (6) ◽

pp. 1552-1565 ◽

Cited By ~ 24

Author(s):

Oryan Makler ◽

Kfir Oved ◽

Nir Netzer ◽

Dana Wolf ◽

Yoram Reiter

Keyword(s):

Antigen Presentation ◽

Human Cells ◽

Direct Visualization

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Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic method

Scientific Reports ◽

10.1038/srep32141 ◽

2016 ◽

Vol 6 (1) ◽

Cited By ~ 44

Author(s):

Aurélien Laguerre ◽

Judy M. Y. Wong ◽

David Monchaud

Keyword(s):

Spectroscopic Method ◽

Human Cells ◽

Direct Visualization ◽

Dna And Rna

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Interferon-β reduces antigen presentation in human cells

Journal of Neuroimmunology ◽

10.1016/0165-5728(94)90313-1 ◽

1994 ◽

Vol 54 (1-2) ◽

pp. 160 ◽

Cited By ~ 1

Author(s):

H. Jiang ◽

R. Milo ◽

V. Wee Yong ◽

P. Swoveland ◽

K.P. Johnson ◽

...

Keyword(s):

Antigen Presentation ◽

Human Cells ◽

Interferon Β

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Synthetic peptides derived from Leishmania proteins and its ability to induce antigen presentation molecules and lymphoproliferation in cell human cells from human volunteers living in Colombia endemic areas.

Frontiers in Immunology ◽

10.3389/conf.fimmu.2015.05.00322 ◽

2015 ◽

Vol 6 ◽

Author(s):

Florez Magda ◽

Granados Diana ◽

Delgado Lucy

Keyword(s):

Antigen Presentation ◽

Synthetic Peptides ◽

Human Cells ◽

Human Volunteers ◽

Endemic Areas

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Repetitive versus monomeric antigen presentation: direct visualization of antibody affinity and specificity

Journal of Structural Biology ◽

10.1016/j.jsb.2003.08.004 ◽

2003 ◽

Vol 143 (3) ◽

pp. 258-262 ◽

Cited By ~ 18

Author(s):

Werner Baschong ◽

Lorenz Hasler ◽

Markus Häner ◽

Joerg Kistler ◽

Ueli Aebi

Keyword(s):

Antigen Presentation ◽

Direct Visualization ◽

Antibody Affinity

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Antigen presentation by murine and human cells to a murine T-cell hybridoma: demonstration of a restriction element associated with a major histocompatibility complex class II determinant(s) shared by both species.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.81.23.7559 ◽

1984 ◽

Vol 81 (23) ◽

pp. 7559-7563 ◽

Cited By ~ 12

Author(s):

S. J. Waters ◽

R. J. Winchester ◽

F. Nagase ◽

G. J. Thorbecke ◽

C. A. Bona

Keyword(s):

Major Histocompatibility Complex ◽

T Cell ◽

Major Histocompatibility Complex Class ◽

Antigen Presentation ◽

Class Ii ◽

Human Cells ◽

Complex Class ◽

Major Histocompatibility ◽

Histocompatibility Complex ◽

Restriction Element

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Direct visualization of phase-separated domains in lipid membranes

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100082315 ◽

1978 ◽

Vol 36 (2) ◽

pp. 290-291

Author(s):

S. W. Hui ◽

T. P. Stewart

Keyword(s):

Lipid Membranes ◽

Structural Information ◽

Freeze Fracture ◽

Biological Molecules ◽

Vacuum Drying ◽

Direct Visualization ◽

X Ray Diffraction ◽

Electron Microscopic ◽

X Ray ◽

Hydrocarbon Chains

Direct electron microscopic study of biological molecules has been hampered by such factors as radiation damage, lack of contrast and vacuum drying. In certain cases, however, the difficulties may be overcome by using redundent structural information from repeating units and by various specimen preservation methods. With bilayers of phospholipids in which both the solid and fluid phases co-exist, the ordering of the hydrocarbon chains may be utilized to form diffraction contrast images. Domains of different molecular packings may be recgnizable by placing properly chosen filters in the diffraction plane. These domains would correspond to those observed by freeze fracture, if certain distinctive undulating patterns are associated with certain molecular packing, as suggested by X-ray diffraction studies. By using an environmental stage, we were able to directly observe these domains in bilayers of mixed phospholipids at various temperatures at which their phases change from misible to inmissible states.

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