scholarly journals Clinical presentation and long‐term outcomes of infantile hypertrophic cardiomyopathy: a European multicentre study

2021 ◽  
Author(s):  
Gabrielle Norrish ◽  
Gali Kolt ◽  
Elena Cervi ◽  
Ella Field ◽  
Kathleen Dady ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Multicentre Study ◽  
Clinical Presentation ◽  
Long Term Outcomes

Abstract 13729: Surgical Myectomy Results in Significantly Improved Long-term Event Rate in Hypertrophic Cardiomyopathy Patients With Severe Left Ventricular Outflow Tract Obstruction

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Milind Y Desai ◽  
Nicholas G Smedira ◽  
Aditya Bhonsale ◽  
Nitesh Ainani ◽  
Maran THamilarasan ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Left Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Left Ventricular ◽  
Outflow Tract ◽  
Long Term Outcomes ◽  
Free Survival ◽  
Left Ventricular Outflow ◽  
Surgical Myectomy

Background: In hypertrophic cardiomyopathy (HCM) with severe left ventricular outflow tract obstruction (LVOTO), surgical myectomy (SM) performed for relief of intractable symptoms is safe and associated with excellent long-term symptom-free survival. In such patients, we sought to determine if SM also results in improvement of long-term outcomes. Methods: We studied 1530 HCM patients with severe LVOTO (50±13 years, 63% men) that were evaluated at our center [excluding <18 years of age, LV ejection fraction (LVEF) <50%, LVOT gradient <30 mm Hg). Clinical, echocardiographic and surgical data were recorded. A composite endpoint of death and/or implantable defibrillator (ICD) discharge was recorded. Results: Hypertension, coronary artery disease (CAD), family history of HCM and syncope were present in 41%, 15%, 17% and 18%, while 73% patients were in Functional Class (FC) ≥ II. Mean LVEF, basal septal thickness, LVOT gradient (resting or provocable) and indexed left atrial dimensions were 62±5%, 2.2±1 cm, 101±39 mm Hg, 2.2±0.4 cm/m2. During 8±6 years of follow-up, 990 (65%) patients underwent SM (of which 65% were isolated SM), while 540 (35%) did not. 94 (6%) patients had alcohol septal ablation (66 in the non myectomy group), while 18% developed atrial fibrillation (AF), and 18% had ICD. There were 169 (11%) events (151 deaths), with 0% 30-day mortality in the SM group. On stepwise multivariable Cox Proportional Hazard analysis, increasing age (Hazard Ratio or HR 1.22 [1.06-1.40]), CAD (HR 1.57 [1.06-2.33]), worsening FC (HR 1.34 [1.05-1.71]) and AF (HR 1.73 [1.23-2.43]) predicted higher events, while SM as a time-dependent covariate (HR 0.58 [0.41-0.81]) was associated with improved event-free survival (all p<0.01). Kaplan-Meier curve showing impact of SM on outcomes is shown in Figure. Conclusion: In HCM patients with severe LVOTO, SM is associated with significant improvement in long-term outcomes when compared to watchful waiting.

scholarly journals Erratum to “Clinical Presentation and Long-Term Outcomes of Systemic Sclerosis Portuguese Patients from a Single Centre Cohort: A EUSTAR Registration Initiative”

2018 ◽  
Vol 31 (9) ◽  
pp. 520
Author(s):  
Carolina Vidal ◽  
Carina Ruano ◽  
Vera Bernardino ◽  
Pedro Lavado Carreira ◽  
Ana Lladó ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Clinical Presentation ◽  
Long Term Outcomes ◽  
Single Centre ◽  
Espírito Santo ◽  
Espirito Santo ◽  
De Medicina

Article published with errors: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10658On page 312, where the authors’ line reads as:Carolina VIDAL1, Carina RUANO2, Vera BERNARDINO3, Pedro LAVADO CARREIRA3, Ana LLADÓ3, Maria Céu SANTOS4, Heidi GRUNER3, António PANARRA3, Nuno RISO3, Maria Francisca MORAES-FONTESAC,1It should read:Carolina VIDAL1,2, Carina RUANO3, Vera BERNARDINO1, Pedro LAVADO CARREIRA1, Ana LLADÓ1, Maria Céu SANTOS4, Heidi GRUNER1, António PANARRA1, Nuno RISO1, Maria Francisca MORAES-FONTESAC,1 On the same page, where the authors’ affiliation on the footer reads as:Serviço de Medicina Interna. Hospital do Divino Espírito Santo de Ponta Delgada. São Miguel. Portugal.Serviço de Radiologia. Hospital de Santa Marta. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.Unidade de Doenças Auto-Imunes/Serviço Medicina 7.2. Hospital de Curry Cabral. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.Laboratório de Imunologia. Centro Hospitalar de Lisboa Central. Lisboa. Portugal. It should read:Unidade de Doenças Auto-Imunes/Serviço Medicina 7.2. Hospital de Curry Cabral. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.Serviço de Medicina Interna. Hospital do Divino Espírito Santo de Ponta Delgada. São Miguel. Portugal.Serviço de Radiologia. Hospital de Santa Marta. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.Laboratório de Imunologia. Centro Hospitalar de Lisboa Central. Lisboa. Portugal.  

scholarly journals Long-term outcomes after cosmetic customized prostheses and dermis fat graft in congenital anophthalmia: a retrospective multicentre study

Eye ◽  
2018 ◽  
Vol 32 (12) ◽  
pp. 1803-1810
Author(s):  
Alessandra Claudia Modugno ◽  
Antonio Giordano Resti ◽  
Giacomilde Mazzone ◽  
Caterina Moretti ◽  
Maria Rosa Terreni ◽  
...  
Keyword(s):  
Multicentre Study ◽  
Fat Graft ◽  
Long Term Outcomes ◽  
Congenital Anophthalmia

scholarly journals Association of Obesity With Adverse Long-term Outcomes in Hypertrophic Cardiomyopathy

2020 ◽  
Vol 5 (1) ◽  
pp. 65 ◽  
Author(s):  
Carlo Fumagalli ◽  
Niccolò Maurizi ◽  
Sharlene M. Day ◽  
Euan A. Ashley ◽  
Michelle Michels ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Long Term Outcomes
Sign in / Sign up

Export Citation Format

Share Document