scholarly journals Genetic effects of anthropogenic habitat fragmentation on remnant animal and plant populations: a meta-analysis

Ecosphere ◽  
2018 ◽  
Vol 9 (10) ◽  
pp. e02488 ◽  
Author(s):  
Daniel R. Schlaepfer ◽  
Brigitte Braschler ◽  
Hans-Peter Rusterholz ◽  
Bruno Baur
2017 ◽  
Vol 215 ◽  
pp. 30-38 ◽  
Author(s):  
Juliana M. de Almeida-Rocha ◽  
Carlos A. Peres ◽  
Leonardo C. Oliveira

1998 ◽  
Vol 46 (6) ◽  
pp. 671 ◽  
Author(s):  
G. J. Starr ◽  
S. M. Carthew

Fragmentation of the landscape by human activity has created small, isolated plant populations. Hakea carinata F. Muell. ex Meissner, a sclerophyllous shrub, is common in isolated fragments of vegetation in South Australia. This study investigated whether habitat fragmentation has caused restrictions to gene flow between populations. Gene diversity (HT = 0.317) is average for similar species but little is held within populations (HS = 0.168) and 46.9% of gene diversity is accounted for between populations. Estimates of gene flow are NM = 0.270 (based on FST) and NM = 0.129 (based on private alleles). Populations are substantially selfing (t = 0.111). Small isolated populations appears to be a long-term evolutionary condition in this species rather than a consequence of habitat fragmentation; however, population extinctions are occurring. Conservation will require the reservation of many populations to represent the genetic variation present in the species.


2020 ◽  
Author(s):  
Eshim S Jami ◽  
Anke R Hammerschlag ◽  
Hill F Ip ◽  
Andrea G Allegrini ◽  
Beben Benyamin ◽  
...  

Internalising symptoms in childhood and adolescence are as heritable as adult depression and anxiety, yet little is known of their molecular basis. This genome-wide association meta-analysis of internalising symptoms included repeated observations from 64,641 individuals, aged between 3 and 18. The N-weighted meta-analysis of overall internalising symptoms (INToverall) detected no genome-wide significant hits and showed low SNP heritability (1.66%, 95% confidence intervals 0.84-2.48%, Neffective=132,260). Stratified analyses showed rater-based heterogeneity in genetic effects, with self-reported internalising symptoms showing the highest heritability (5.63%, 95% confidence intervals 3.08-8.18%). Additive genetic effects on internalising symptoms appeared stable over age, with overlapping estimates of SNP heritability from early-childhood to adolescence. Gene-based analyses showed significant associations with three genes: WNT3 (p=1.13×10-06), CCL26 (p=1.88×10-06), and CENPO (p=2.54×10-06). Of these, WNT3 was previously associated with neuroticism, with which INToverall also shared a strong genetic correlation (rg=0.76). Genetic correlations were also observed with adult anxiety, depression, and the wellbeing spectrum (|rg|> 0.70), as well as with insomnia, loneliness, attention-deficit hyperactivity disorder, autism, and childhood aggression (range |rg|=0.42-0.60), whereas there were no robust associations with schizophrenia, bipolar disorder, obsessive-compulsive disorder, or anorexia nervosa. Overall, childhood and adolescent internalising symptoms share substantial genetic vulnerabilities with adult internalising disorders and other childhood psychiatric traits, which could explain both the persistence of internalising symptoms over time, and the high comorbidity amongst childhood psychiatric traits. Reducing phenotypic heterogeneity in childhood samples will be key in paving the way to future GWAS success.


2017 ◽  
Vol 37 ◽  
pp. 61-66
Author(s):  
G Grilli ◽  
S Longo ◽  
PY Huais ◽  
M Pereyra ◽  
E Verga ◽  
...  

2020 ◽  
Vol 29 (7) ◽  
pp. 1265-1279 ◽  
Author(s):  
Tim S. Doherty ◽  
Sara Balouch ◽  
Kristian Bell ◽  
Thomas J. Burns ◽  
Anat Feldman ◽  
...  

2007 ◽  
Vol 170 (1) ◽  
pp. 128-142 ◽  
Author(s):  
C. J. Clark ◽  
J. R. Poulsen ◽  
D. J. Levey ◽  
C. W. Osenberg

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