Association between broadly defined bulimia nervosa and drug use disorders: Common genetic and environmental influences

2007 ◽  
Vol 40 (8) ◽  
pp. 673-678 ◽  
Author(s):  
Jessica H. Baker ◽  
Suzanne E. Mazzeo ◽  
Kenneth S. Kendler
2021 ◽  
Vol 11 (33) ◽  
pp. 195-203
Author(s):  
Antonio Dean Barbosa Marques ◽  
July Grassiely de Oliveira Branco ◽  
Marcos Venicios Barbosa Marques ◽  
Talison Joseph Gonçalves Leitão ◽  
Guilherme Alves da Silva ◽  
...  

Objetivou-se descrever a associação dos transtornos de compulsão alimentar com o uso de álcool e outras drogas. Trata-se de uma revisão integrativa da literatura realizada no mês de julho de 2018 nas bases de dados: Cumulative Index to Nursing and Allied Health Literature (CINAHL), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), PsycINFO, SciVerse Scopus e portal da PubMed. Foram incluídos 15 artigos que atenderam aos critérios do estudo. Os estudos analisados apontam que os transtornos alimentares surgem com maior frequência na adolescência e em mulheres. Destaca-se a bulimia nervosa como a mais associada aos transtornos relacionados ao uso de álcool e outras drogas do que os demais transtornos alimentares. Conclui-se que o diagnóstico precoce e uma abordagem terapêutica adequada dos transtornos alimentares são fundamentais para o manejo clínico e o prognóstico destas condições.Descritores: Transtorno da Compulsão Alimentar, Transtorno Relacionados ao Uso de Substâncias, Saúde Mental. Food compulsion and its association with drug use: integrative reviewAbstract: This study aimed to describe the association of binge eating disorders with the use of alcohol and other drugs. This is an integrative literature review conducted in July 2018 in the databases: Cumulative Index to Nursing and Allied Health Literature (CINAHL), Latin American and Caribbean Literature on Health Sciences (LILACS), PsycINFO, SciVerse Scopus, and PubMed portal. We included 15 articles that met the study criteria. The studies analyzed indicate that eating disorders appear more frequently in adolescence and women. Bulimia nervosa is more associated with alcohol and other drug use disorders than other eating disorders. It is concluded that early diagnosis and an appropriate therapeutic approach to eating disorders are fundamental for the clinical management and prognosis of these conditions.Descriptors: Binge Eating Disorder, Substance-Related Disorders, Mental Health. La compulsión por la comida y su asociación con el consumo de drogas: revisión integradoraResumen: Este estudio tenía como objetivo describir la asociación de trastornos de la alimentación por atracones con el consumo de alcohol y otras drogas. Esta es una revisión bibliografía integradora realizada en julio de 2018 en las bases de datos: índice acumulado de enfermería y literatura de salud aliada (CINAHL), literatura latinoamericana y caribeña sobre ciencias de la salud (LILACS), PsycINFO, SciVerse Scopus y portal PubMed. Incluimos 15 artículos que cumplían con los criterios de estudio. Los estudios analizados indican que los trastornos alimentarios aparecen con mayor frecuencia en la adolescencia y en las mujeres. Bulimia nerviosa está más asociada con el alcohol y otros trastornos del consumo de drogas que otros trastornos de la alimentación. Se concluye que el diagnóstico precoz y un enfoque terapéutico adecuado para los trastornos de la alimentación son fundamentales para el manejo clínico y el pronóstico de estas condiciones.Descriptores: Trastorno por Atracón, Trastornos Relacionados con Substancias, Salud Mental.


2001 ◽  
Vol 120 (5) ◽  
pp. A409-A409
Author(s):  
H ELSERAG ◽  
M KUNIK ◽  
P RICHARDSON ◽  
L RABENECK

2021 ◽  
Vol 30 ◽  
Author(s):  
Laila Hasmi ◽  
Lotta-Katrin Pries ◽  
Margreet ten Have ◽  
Ron de Graaf ◽  
Saskia van Dorsselaer ◽  
...  

Abstract Aims Although attenuated psychotic symptoms in the psychosis clinical high-risk state (CHR-P) almost always occur in the context of a non-psychotic disorder (NPD), NPD is considered an undesired ‘comorbidity’ epiphenomenon rather than an integral part of CHR-P itself. Prospective work, however, indicates that much more of the clinical psychosis incidence is attributable to prior mood and drug use disorders than to psychosis clinical high-risk states per se. In order to examine this conundrum, we analysed to what degree the ‘risk’ in CHR-P is indexed by co-present NPD rather than attenuated psychosis per se. Methods We examined the incidence of early psychotic experiences (PE) with and without NPD (mood disorders, anxiety disorders, alcohol/drug use disorders), in a prospective general population cohort (n = 6123 at risk of incident PE at baseline). Four interview waves were conducted between 2007 and 2018 (NEMESIS-2). The incidence of PE, alone (PE-only) or with NPD (PE + NPD) was calculated, as were differential associations with schizophrenia polygenic risk score (PRS-Sz), environmental, demographical, clinical and cognitive factors. Results The incidence of PE + NPD (0.37%) was lower than the incidence of PE-only (1.04%), representing around a third of the total yearly incidence of PE. Incident PE + NPD was, in comparison with PE-only, differentially characterised by poor functioning, environmental risks, PRS-Sz, positive family history, prescription of antipsychotic medication and (mental) health service use. Conclusions The risk in ‘clinical high risk’ states is mediated not by attenuated psychosis per se but specifically the combination of attenuated psychosis and NPD. CHR-P/APS research should be reconceptualised from a focus on attenuated psychotic symptoms with exclusion of non-psychotic DSM-disorders, as the ‘pure' representation of a supposedly homotypic psychosis risk state, towards a focus on poor-outcome NPDs, characterised by a degree of psychosis admixture, on the pathway to psychotic disorder outcomes.


2015 ◽  
Vol 76 (5) ◽  
pp. 721-732 ◽  
Author(s):  
Roxanne Upah ◽  
Theodore Jacob ◽  
Rumi Kato Price
Keyword(s):  
Drug Use ◽  

Author(s):  
Sarah C Snow ◽  
Gregg C Fonarow ◽  
Joseph A Ladapo ◽  
Donna L Washington ◽  
Katherine Hoggatt ◽  
...  

Background: Several cardiotoxic substances contribute to the development of heart failure (HF). The burden of comorbid substance use disorders (SUD) among patients with HF is under-characterized. Objectives: To describe the national burden of comorbid SUD (tobacco, alcohol, or drug use disorders) among hospitalized HF patients in the U.S. Methods: We used data from the 2014 National Inpatient Sample to calculate the proportion of hospitalizations for a primary HF admission with tobacco, alcohol, or drug use disorder diagnoses, accounting for demographic factors. Drug use disorder analysis was further sub-divided into specific illicit substance categories. Results: There were a total of 989,080 HF hospitalizations of which 35.3% (n=348,995) had a documented SUD. Tobacco use disorder (TUD) was most common (n= 327,220, 33.1%) followed by drug use disorder (DUD) (n=34,600, 3.5%) and alcohol use disorder (AUD) (n=34,285, 3.5%). Female sex was associated with less TUD (OR 0.59; 95% CI, 0.58-0.60), AUD (OR 0.23; 95% CI, 0.22-0.25) or DUD (OR 0.58; 95% CI 0.55-0.62). Tobacco, alcohol, cocaine, and opioid use disorders were highest among HF patients age 45 to 55, while cannabis and amphetamine use was highest in those <45 years. Native American race (versus White) was associated with increased risk of AUD (OR 1.67; 95% CI 1.27-2.20). Black race was associated with increased risk of AUD (OR 1.09; 95% CI 1.02-1.16) or DUD (OR 1.63; 95% CI 1.53-1.74). Medicaid insurance (versus Medicare) was associated with greater TUD (OR 1.27; 95% CI 1.23-1.32), AUD (OR 1.74; 95% CI 1.62-1.87), and DUD (OR 2.15; 95% CI 2.01-2.30). Decreasing quartiles of median household income were associated with increasing SUD. Conclusions: Comorbid SUD disproportionately affects certain HF populations, including men, younger age groups, lower SES patients, and race/ethnic minorities. Further research on interventions to improve prevention and treatment of SUD among hospitalized HF patients are needed given the high rates of SUD in this population. Systematically screening hospitalized HF patients for SUD may reveal opportunities for treatment and secondary prevention.


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