scholarly journals The role of sensory innervation in cornea‐lens regeneration

2019 ◽  
Vol 248 (7) ◽  
pp. 530-544
Author(s):  
Kimberly J. Perry ◽  
Paul W. Hamilton ◽  
Surabhi Sonam ◽  
Ratnakar Singh ◽  
Jonathan J. Henry
2009 ◽  
Vol 613 (1-3) ◽  
pp. 128-134 ◽  
Author(s):  
Ivani A. Desouza ◽  
Enilton A. Camargo ◽  
Nadia S. Mariano ◽  
João B. Optiz-Neto ◽  
Jorge S. Resende ◽  
...  

2010 ◽  
Vol 19 (3) ◽  
pp. 64-67
Author(s):  
Paul Hyman

The purpose of this manuscript is to inform clinicians working with infants who are tube fed about the brain-gut connections that may influence adaptation to oral feedings. Developmental changes in motility and sensory innervation are constant as brain and gut mature in the first several years. We hypothesized that chronically ill neonates are exposed to multiple pain stimuli during hospitalization, leaving them susceptible to hyperalgesia and chronic pain. Hyperalgesia in the abdomen, chest, pharynx, or face may be cause for food refusal. In patients who are tube fed who failed behavioral modification to teach eating, treatment of peripheral nerve and central nervous system hyperalgesia may be required before behavioral modification will work. We designed a 14 week outpatient protocol for moving infants and toddlers who are tube fed from tube to oral feeding using pain rehabilitation strategies. We used 8 weeks of post-pyloric feeding, eliminating stimuli to the oropharynx, esophagus, or stomach. We treated with amitriptyline and/or gabapentin to desensitize sensory receptors and central nervous system arousal. After 8 weeks, we gave the appetite stimulant megesterol for another 6 weeks. Five days after initiation of megesterol, we initiated a 1-hour/night schedule to withdraw tube feedings. In a small, uncontrolled study, all 9 children moved from tube to oral feedings.


1975 ◽  
Vol 191 (2) ◽  
pp. 233-251 ◽  
Author(s):  
Leah A. Williams ◽  
Linda T. Higginbotham

1986 ◽  
Vol 240 (3) ◽  
pp. 343-351 ◽  
Author(s):  
Thomas G. Connelly ◽  
M. Sean Green ◽  
Walter M. Sahijdak ◽  
Robert M. Loyd

2006 ◽  
Vol 123 (11) ◽  
pp. 793-800 ◽  
Author(s):  
Toshinori Hayashi ◽  
Nobuhiko Mizuno ◽  
Ritsuko Takada ◽  
Shinji Takada ◽  
Hisato Kondoh
Keyword(s):  

1997 ◽  
Vol 356 (3) ◽  
pp. 356-363 ◽  
Author(s):  
P. Ferdinandy ◽  
Tamás Csont ◽  
Csaba Csonka ◽  
Marianna Török ◽  
Mária Dux ◽  
...  

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